/* There are a total of 2 entries in the algebraic variable array. There are a total of 8 entries in each of the rate and state variable arrays. There are a total of 11 entries in the constant variable array. */ /* * VOI is time in component environment (second). * STATES[0] is Ca_m in component Ca_m (micromolar). * ALGEBRAIC[0] is J_min in component J_min (micromolar). * ALGEBRAIC[1] is J_mout in component J_mout (micromolar). * CONSTANTS[0] is k_min in component J_min (micromolar). * STATES[1] is Ca_cyt in component Ca_cyt (micromolar). * CONSTANTS[1] is K_m in component J_min (micromolar). * CONSTANTS[2] is n in component J_min (micromolar). * CONSTANTS[3] is k_mout in component J_mout (micromolar). * STATES[2] is J_ERch in component J_ERch (micromolar). * STATES[3] is J_ERpump in component J_ERpump (micromolar). * STATES[4] is J_ERleak in component J_ERleak (micromolar). * STATES[5] is J_in in component J_in (micromolar). * STATES[6] is J_out in component J_out (micromolar). * STATES[7] is Ca_ER in component Ca_ER (micromolar). * CONSTANTS[4] is K_ch in component J_ERch (micromolar). * CONSTANTS[5] is k_ERch in component J_ERch (micromolar). * CONSTANTS[6] is K_ERpump in component J_ERpump (micromolar). * CONSTANTS[7] is K_ERleak in component J_ERleak (micromolar). * CONSTANTS[8] is K_in in component J_in (micromolar). * CONSTANTS[9] is K_out in component J_out (micromolar). * RATES[0] is d/dt Ca_m in component Ca_m (micromolar). * RATES[1] is d/dt Ca_cyt in component Ca_cyt (micromolar). * RATES[7] is d/dt Ca_ER in component Ca_ER (micromolar). * RATES[2] is d/dt J_ERch in component J_ERch (micromolar). * RATES[3] is d/dt J_ERpump in component J_ERpump (micromolar). * RATES[4] is d/dt J_ERleak in component J_ERleak (micromolar). * RATES[5] is d/dt J_in in component J_in (micromolar). * RATES[6] is d/dt J_out in component J_out (micromolar). */ void initConsts(double* CONSTANTS, double* RATES, double *STATES) { STATES[0] = 0.1; CONSTANTS[0] = 330; STATES[1] = 0.1; CONSTANTS[1] = 1.6; CONSTANTS[2] = 8; CONSTANTS[3] = 0.5; STATES[2] = 0.1; STATES[3] = 0.1; STATES[4] = 0.1; STATES[5] = 0.1; STATES[6] = 0.1; STATES[7] = 0.1; CONSTANTS[4] = 3; CONSTANTS[5] = 0.1; CONSTANTS[6] = 2; CONSTANTS[7] = 0.01; CONSTANTS[8] = 0.8; CONSTANTS[9] = 1; CONSTANTS[10] = CONSTANTS[8]; } void computeRates(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC) { RATES[5] = CONSTANTS[10]; RATES[7] = (STATES[3] - STATES[4]) - STATES[2]; RATES[2] = (( CONSTANTS[5]*pow(STATES[1], 4.00000))/(pow(CONSTANTS[4], 4.00000)+pow(STATES[1], 4.00000)))*STATES[7]; RATES[3] = ( CONSTANTS[6]*STATES[1])/1.00000; RATES[4] = CONSTANTS[7]*STATES[7]; RATES[6] = ( CONSTANTS[9]*STATES[1])/1.00000; ALGEBRAIC[0] = CONSTANTS[0]*(pow(STATES[1], CONSTANTS[2])/(pow(CONSTANTS[1], CONSTANTS[2])+pow(STATES[1], CONSTANTS[2]))); ALGEBRAIC[1] = ( CONSTANTS[3]*STATES[0])/1.00000; RATES[0] = ALGEBRAIC[0] - ALGEBRAIC[1]; RATES[1] = ((((STATES[2] - STATES[3])+STATES[4]+STATES[5]) - STATES[6])+ALGEBRAIC[1]) - ALGEBRAIC[0]; } void computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC) { ALGEBRAIC[0] = CONSTANTS[0]*(pow(STATES[1], CONSTANTS[2])/(pow(CONSTANTS[1], CONSTANTS[2])+pow(STATES[1], CONSTANTS[2]))); ALGEBRAIC[1] = ( CONSTANTS[3]*STATES[0])/1.00000; }