C
C There are a total of 15 entries in the algebraic variable array.
C There are a total of 4 entries in each of the rate and state variable arrays.
C There are a total of 42 entries in the constant variable array.
C
C
C VOI is time in component environment (day).
C STATES(1) is OB_p in component OB_p (dimensionless).
C CONSTS(1) is D_OB_u in component OB_p (first_order_rate_constant).
C CONSTS(2) is pd_OB_p in component OB_p (first_order_rate_constant).
C ALGBRC(3) is pi_TGF_beta_act in component TGF_beta (dimensionless).
C ALGBRC(4) is pi_TGF_beta_rep in component TGF_beta (dimensionless).
C CONSTS(3) is D_OB_p in component model_parameters (first_order_rate_constant).
C STATES(2) is OB_a in component OB_a (dimensionless).
C CONSTS(4) is OB_a_initial in component OB_a (dimensionless).
C CONSTS(5) is A_OB_a in component OB_a (first_order_rate_constant).
C CONSTS(6) is pd_OB_a in component OB_a (first_order_rate_constant).
C STATES(3) is OC_a in component OC_a (dimensionless).
C CONSTS(7) is OC_a_initial in component OC_a (dimensionless).
C ALGBRC(1) is D_OC_p in component OC_a (first_order_rate_constant).
C CONSTS(8) is A_OC_a in component OC_a (first_order_rate_constant).
C CONSTS(9) is pd_OC_a in component OC_a (first_order_rate_constant).
C ALGBRC(11) is pi_RANKL_act in component RANKL (dimensionless).
C STATES(4) is BV in component BV (dimensionless).
C CONSTS(10) is k_form in component BV (first_order_rate_constant).
C CONSTS(11) is k_res in component BV (first_order_rate_constant).
C ALGBRC(2) is TGF_beta in component TGF_beta (dimensionless).
C CONSTS(12) is KD_TGF_repress in component TGF_beta (pM).
C CONSTS(13) is KD_TGF_activate in component TGF_beta (pM).
C CONSTS(14) is alpha in component TGF_beta (pM).
C CONSTS(15) is S_TGF_beta in component TGF_beta (pM).
C CONSTS(16) is Deg_TGF_beta in component TGF_beta (pM).
C CONSTS(41) is pi_PTH_act in component PTH (dimensionless).
C CONSTS(42) is pi_PTH_rep in component PTH (dimensionless).
C CONSTS(17) is beta_PTH in component PTH (flux).
C CONSTS(18) is Deg_PTH in component PTH (first_order_rate_constant).
C CONSTS(19) is P_PTH_d in component PTH (flux).
C CONSTS(38) is PTH_tot in component PTH (pM).
C CONSTS(20) is KD_PTH_repress in component PTH (pM).
C CONSTS(21) is KD_PTH_activate in component PTH (pM).
C ALGBRC(6) is OPG in component OPG (pM).
C CONSTS(22) is beta_OPG in component OPG (flux).
C CONSTS(23) is beta1_OB_p_OPG in component OPG (dimensionless).
C CONSTS(24) is beta2_OB_a_OPG in component OPG (dimensionless).
C CONSTS(25) is OPG_max in component OPG (pM).
C ALGBRC(5) is OPG_eff in component OPG (flux).
C CONSTS(26) is P_OPG_d in component OPG (flux).
C CONSTS(27) is Deg_OPG in component OPG (first_order_rate_constant).
C ALGBRC(7) is Degr_OPG in component OPG (flux).
C ALGBRC(8) is prod_OPG in component OPG (flux).
C ALGBRC(10) is RANKL in component RANKL (dimensionless).
C CONSTS(28) is K_A2_RANKL in component RANKL (dimensionless).
C CONSTS(29) is K_A1_RANKL in component RANKL (dimensionless).
C CONSTS(30) is RANK in component RANKL (pM).
C ALGBRC(9) is RANKL_eff in component RANKL (pM).
C ALGBRC(12) is RANKL_tot in component RANKL (pM).
C CONSTS(39) is K_RANKL_OB_p in component RANKL (pM).
C CONSTS(40) is K_RANKL_OB_a in component RANKL (pM).
C ALGBRC(13) is OPG_RANKL in component RANKL (pM).
C CONSTS(31) is R_RANKL in component RANKL (dimensionless).
C ALGBRC(14) is RANKL_RANK in component RANKL (pM).
C ALGBRC(15) is pd_RANKL in component RANKL (flux).
C CONSTS(32) is P_RANKL_d in component RANKL (flux).
C CONSTS(33) is R1_OB_p_RANKL in component RANKL (pM).
C CONSTS(34) is R2_OB_a_RANKL in component RANKL (pM).
C CONSTS(35) is beta_RANKL in component RANKL (flux).
C CONSTS(36) is Deg_RANKL in component RANKL (first_order_rate_constant).
C CONSTS(37) is KD_RANKL_activate in component RANKL (pM).
C RATES(1) is d/dt OB_p in component OB_p (dimensionless).
C RATES(2) is d/dt OB_a in component OB_a (dimensionless).
C RATES(3) is d/dt OC_a in component OC_a (dimensionless).
C RATES(4) is d/dt BV in component BV (dimensionless).
C
      SUBROUTINE initConsts(CONSTS, RATES, STATES)
      REAL CONSTS(*), RATES(*), STATES(*)
      STATES(1) = 6.194e-4
      CONSTS(1) = 7.000e-04
      CONSTS(2) = 0.0
      CONSTS(3) = 2.674e-1
      STATES(2) = 5.584e-4
      CONSTS(4) = 5.584e-4
      CONSTS(5) = 1.890e-1
      CONSTS(6) = 0.0
      STATES(3) = 8.070e-4
      CONSTS(7) = 8.070e-4
      CONSTS(8) = 7.000e-1
      CONSTS(9) = 0.0
      STATES(4) = 100.0
      CONSTS(10) = 1.571e0
      CONSTS(11) = 1.000e0
      CONSTS(12) = 1.416e-3
      CONSTS(13) = 4.545e-3
      CONSTS(14) = 1.0
      CONSTS(15) = 0.0
      CONSTS(16) = 1.0
      CONSTS(17) = 2.500e2
      CONSTS(18) = 8.600e1
      CONSTS(19) = 0.0
      CONSTS(20) = 2.226e-1
      CONSTS(21) = 1.500e2
      CONSTS(22) = 1.464e8
      CONSTS(23) = 0.0
      CONSTS(24) = 1.0
      CONSTS(25) = 2.000e8
      CONSTS(26) = 0.0
      CONSTS(27) = 3.500e-1
      CONSTS(28) = 3.412e-2
      CONSTS(29) = 1.000e-3
      CONSTS(30) = 1.000e1
      CONSTS(31) = 3.000e6
      CONSTS(32) = 0.0
      CONSTS(33) = 1.0
      CONSTS(34) = 0.0
      CONSTS(35) = 1.684e4
      CONSTS(36) = 1.013e1
      CONSTS(37) = 1.306e1
      CONSTS(38) = (CONSTS(17)+CONSTS(19))/CONSTS(18)
      CONSTS(39) =  CONSTS(33)*CONSTS(31)
      CONSTS(40) =  CONSTS(34)*CONSTS(31)
      CONSTS(41) = CONSTS(38)/(CONSTS(38)+CONSTS(21))
      CONSTS(42) = 1.00000/(1.00000+CONSTS(38)/CONSTS(20))
      RETURN
      END
      SUBROUTINE computeRates(VOI, CONSTS,  RATES, STATES, ALGBRC)
      REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*)
      RATES(4) =  CONSTS(10)*(STATES(2) - CONSTS(4)) -  CONSTS(11)*(STATES(3) - CONSTS(7))
      ALGBRC(2) = ( CONSTS(14)*CONSTS(11)*STATES(3)+CONSTS(15))/CONSTS(16)
      ALGBRC(3) = ALGBRC(2)/(CONSTS(13)+ALGBRC(2))
      ALGBRC(4) = 1.00000/(1.00000+ALGBRC(2)/CONSTS(12))
      RATES(1) = ( CONSTS(1)*ALGBRC(3) -  CONSTS(3)*ALGBRC(4)*STATES(1))+CONSTS(2)
      RATES(2) = ( CONSTS(3)*ALGBRC(4)*STATES(1) -  CONSTS(5)*STATES(2))+CONSTS(6)
      ALGBRC(1) = TERNRY(VOI.GT.0.00000.AND.VOI.LE.100.000, 0.0210000, 0.00210000)
      ALGBRC(5) =  ( CONSTS(23)*CONSTS(22)*STATES(1)+ CONSTS(24)*CONSTS(22)*STATES(2))*CONSTS(42)
      ALGBRC(6) = (ALGBRC(5)+CONSTS(26))/(ALGBRC(5)/CONSTS(25)+CONSTS(27))
      ALGBRC(9) =  ( CONSTS(39)*STATES(1)+ CONSTS(40)*STATES(2))*CONSTS(41)
      ALGBRC(10) = ( (ALGBRC(9)/(1.00000+ CONSTS(29)*ALGBRC(6)+ CONSTS(28)*CONSTS(30)))*(CONSTS(35)+CONSTS(32)))/(CONSTS(35)+ CONSTS(36)*ALGBRC(9))
      ALGBRC(11) = ALGBRC(10)/(CONSTS(37)+ALGBRC(10))
      RATES(3) = ( ALGBRC(1)*ALGBRC(11) -  CONSTS(8)*ALGBRC(3)*STATES(3))+CONSTS(9)
      RETURN
      END
      SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC)
      REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*)
      ALGBRC(2) = ( CONSTS(14)*CONSTS(11)*STATES(3)+CONSTS(15))/CONSTS(16)
      ALGBRC(3) = ALGBRC(2)/(CONSTS(13)+ALGBRC(2))
      ALGBRC(4) = 1.00000/(1.00000+ALGBRC(2)/CONSTS(12))
      ALGBRC(1) = TERNRY(VOI.GT.0.00000.AND.VOI.LE.100.000, 0.0210000, 0.00210000)
      ALGBRC(5) =  ( CONSTS(23)*CONSTS(22)*STATES(1)+ CONSTS(24)*CONSTS(22)*STATES(2))*CONSTS(42)
      ALGBRC(6) = (ALGBRC(5)+CONSTS(26))/(ALGBRC(5)/CONSTS(25)+CONSTS(27))
      ALGBRC(9) =  ( CONSTS(39)*STATES(1)+ CONSTS(40)*STATES(2))*CONSTS(41)
      ALGBRC(10) = ( (ALGBRC(9)/(1.00000+ CONSTS(29)*ALGBRC(6)+ CONSTS(28)*CONSTS(30)))*(CONSTS(35)+CONSTS(32)))/(CONSTS(35)+ CONSTS(36)*ALGBRC(9))
      ALGBRC(11) = ALGBRC(10)/(CONSTS(37)+ALGBRC(10))
      ALGBRC(7) =  CONSTS(27)*ALGBRC(6)
      ALGBRC(8) =  ALGBRC(5)*(1.00000 - ALGBRC(6)/CONSTS(25))+CONSTS(26)
      ALGBRC(12) =  ALGBRC(10)*(1.00000+ CONSTS(29)*ALGBRC(6)+ CONSTS(28)*CONSTS(30))
      ALGBRC(13) =  CONSTS(29)*ALGBRC(6)*ALGBRC(10)
      ALGBRC(14) =  CONSTS(28)*ALGBRC(10)*CONSTS(30)
      ALGBRC(15) = ( CONSTS(35)*(1.00000 - ALGBRC(12)/ALGBRC(9)) -  CONSTS(36)*ALGBRC(12))+CONSTS(32)
      RETURN
      END
      REAL FUNCTION TERNRY(TEST, VALA, VALB)
      LOGICAL TEST
      REAL VALA, VALB
      IF (TEST) THEN
        TERNRY = VALA
      ELSE
        TERNRY = VALB
      ENDIF
      RETURN
      END