C C There are a total of 20 entries in the algebraic variable array. C There are a total of 4 entries in each of the rate and state variable arrays. C There are a total of 51 entries in the constant variable array. C C C VOI is t in component BG_HKE (second). C CONSTS(1) is R in component params_BG (J_per_K_mol). C CONSTS(2) is T in component params_BG (kelvin). C CONSTS(3) is K_Ki in component params_BG (per_fmol). C CONSTS(4) is K_Ko in component params_BG (per_fmol). C CONSTS(5) is K_Pi in component params_BG (per_fmol). C CONSTS(6) is K_ATPi in component params_BG (per_fmol). C CONSTS(7) is K_Hi in component params_BG (per_fmol). C CONSTS(8) is K_Ho in component params_BG (per_fmol). C CONSTS(9) is K_ADPi in component params_BG (per_fmol). C CONSTS(34) is q_init_Ki in component params_BG (fmol). C CONSTS(31) is q_init_Ko in component params_BG (fmol). C CONSTS(37) is q_init_Pi in component params_BG (fmol). C CONSTS(40) is q_init_ATPi in component params_BG (fmol). C CONSTS(43) is q_init_Hi in component params_BG (fmol). C CONSTS(46) is q_init_Ho in component params_BG (fmol). C CONSTS(49) is q_init_ADPi in component params_BG (fmol). C CONSTS(10) is K_1 in component params_BG (per_fmol). C CONSTS(11) is q_init_1 in component params_BG (fmol). C CONSTS(12) is K_2 in component params_BG (per_fmol). C CONSTS(13) is q_init_2 in component params_BG (fmol). C CONSTS(14) is K_3 in component params_BG (per_fmol). C CONSTS(15) is q_init_3 in component params_BG (fmol). C CONSTS(16) is K_4 in component params_BG (per_fmol). C CONSTS(17) is q_init_4 in component params_BG (fmol). C CONSTS(18) is kappa_r1 in component params_BG (fmol_per_s). C CONSTS(19) is kappa_r2 in component params_BG (fmol_per_s). C CONSTS(20) is kappa_r3 in component params_BG (fmol_per_s). C CONSTS(21) is kappa_r4 in component params_BG (fmol_per_s). C CONSTS(36) is mu_Ki in component BG_HKE (J_per_mol). C CONSTS(33) is mu_Ko in component BG_HKE (J_per_mol). C CONSTS(39) is mu_Pi in component BG_HKE (J_per_mol). C CONSTS(42) is mu_ATPi in component BG_HKE (J_per_mol). C CONSTS(45) is mu_Hi in component BG_HKE (J_per_mol). C CONSTS(48) is mu_Ho in component BG_HKE (J_per_mol). C CONSTS(51) is mu_ADPi in component BG_HKE (J_per_mol). C ALGBRC(1) is mu_1 in component BG_HKE (J_per_mol). C ALGBRC(19) is v_1 in component BG_HKE (fmol_per_s). C ALGBRC(2) is mu_2 in component BG_HKE (J_per_mol). C ALGBRC(11) is v_2 in component BG_HKE (fmol_per_s). C ALGBRC(3) is mu_3 in component BG_HKE (J_per_mol). C ALGBRC(15) is v_3 in component BG_HKE (fmol_per_s). C ALGBRC(4) is mu_4 in component BG_HKE (J_per_mol). C ALGBRC(20) is v_4 in component BG_HKE (fmol_per_s). C ALGBRC(5) is A_f_r1 in component BG_HKE (J_per_mol). C ALGBRC(7) is v_r1 in component BG_HKE (fmol_per_s). C ALGBRC(6) is A_r_r1 in component BG_HKE (J_per_mol). C ALGBRC(8) is A_f_r2 in component BG_HKE (J_per_mol). C ALGBRC(10) is v_r2 in component BG_HKE (fmol_per_s). C ALGBRC(9) is A_r_r2 in component BG_HKE (J_per_mol). C ALGBRC(12) is A_f_r3 in component BG_HKE (J_per_mol). C ALGBRC(14) is v_r3 in component BG_HKE (fmol_per_s). C ALGBRC(13) is A_r_r3 in component BG_HKE (J_per_mol). C ALGBRC(16) is A_f_r4 in component BG_HKE (J_per_mol). C ALGBRC(18) is v_r4 in component BG_HKE (fmol_per_s). C ALGBRC(17) is A_r_r4 in component BG_HKE (J_per_mol). C CONSTS(35) is q_Ki in component BG_HKE (fmol). C CONSTS(32) is q_Ko in component BG_HKE (fmol). C CONSTS(41) is q_ATPi in component BG_HKE (fmol). C CONSTS(38) is q_Pi in component BG_HKE (fmol). C CONSTS(44) is q_Hi in component BG_HKE (fmol). C CONSTS(47) is q_Ho in component BG_HKE (fmol). C CONSTS(50) is q_ADPi in component BG_HKE (fmol). C STATES(1) is q_1 in component BG_HKE (fmol). C STATES(2) is q_2 in component BG_HKE (fmol). C STATES(3) is q_3 in component BG_HKE (fmol). C STATES(4) is q_4 in component BG_HKE (fmol). C CONSTS(22) is V_i in component params_BG (pL). C CONSTS(23) is K_i in component params_BG (mM). C CONSTS(24) is K_o in component params_BG (mM). C CONSTS(25) is ATPi in component params_BG (mM). C CONSTS(26) is Hi in component params_BG (mM). C CONSTS(27) is Ho in component params_BG (mM). C CONSTS(28) is ADPi in component params_BG (mM). C CONSTS(29) is Pi in component params_BG (mM). C CONSTS(30) is V_o in component params_BG (pL). C RATES(1) is d/dt q_1 in component BG_HKE (fmol). C RATES(2) is d/dt q_2 in component BG_HKE (fmol). C RATES(3) is d/dt q_3 in component BG_HKE (fmol). C RATES(4) is d/dt q_4 in component BG_HKE (fmol). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) CONSTS(1) = 8.31 CONSTS(2) = 273.15 CONSTS(3) = 149.65 CONSTS(4) = 149.65 CONSTS(5) = 149.65 CONSTS(6) = 149.65 CONSTS(7) = 149.65 CONSTS(8) = 149.65 CONSTS(9) = 149.65 CONSTS(10) = 33.20 CONSTS(11) = 0.0017 CONSTS(12) = 4.25e+03 CONSTS(13) = 0.0017 CONSTS(14) = 344.59 CONSTS(15) = 0.0017 CONSTS(16) = 1.99 CONSTS(17) = 0.0017 CONSTS(18) = 0.36 CONSTS(19) = 0.26 CONSTS(20) = 1.01e+05 CONSTS(21) = 1.01e+04 CONSTS(22) = 0.09 CONSTS(23) = 10 CONSTS(24) = 1e-5 CONSTS(25) = 1e-5 CONSTS(26) = 1e-5 CONSTS(27) = 1e-5 CONSTS(28) = 1e-5 CONSTS(29) = 1e-5 CONSTS(30) = 0.09 CONSTS(31) = CONSTS(24)*CONSTS(30) CONSTS(32) = CONSTS(31) CONSTS(33) = CONSTS(1)*CONSTS(2)*log( CONSTS(4)*CONSTS(32)) CONSTS(34) = CONSTS(23)*CONSTS(22) CONSTS(35) = CONSTS(34) CONSTS(36) = CONSTS(1)*CONSTS(2)*log( CONSTS(3)*CONSTS(35)) CONSTS(37) = CONSTS(29)*CONSTS(22) CONSTS(38) = CONSTS(37) CONSTS(39) = CONSTS(1)*CONSTS(2)*log( CONSTS(5)*CONSTS(38)) CONSTS(40) = CONSTS(25)*CONSTS(22) CONSTS(41) = CONSTS(40) CONSTS(42) = CONSTS(1)*CONSTS(2)*log( CONSTS(6)*CONSTS(41)) CONSTS(43) = CONSTS(26)*CONSTS(22) CONSTS(44) = CONSTS(43) CONSTS(45) = CONSTS(1)*CONSTS(2)*log( CONSTS(7)*CONSTS(44)) CONSTS(46) = CONSTS(27)*CONSTS(22) CONSTS(47) = CONSTS(46) CONSTS(48) = CONSTS(1)*CONSTS(2)*log( CONSTS(8)*CONSTS(47)) CONSTS(49) = CONSTS(28)*CONSTS(22) CONSTS(50) = CONSTS(49) CONSTS(51) = CONSTS(1)*CONSTS(2)*log( CONSTS(9)*CONSTS(50)) STATES(1) = CONSTS(11) STATES(2) = CONSTS(13) STATES(3) = CONSTS(15) STATES(4) = CONSTS(17) RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(1) = CONSTS(1)*CONSTS(2)*log( CONSTS(10)*STATES(1)) ALGBRC(5) = ALGBRC(1)+CONSTS(33) ALGBRC(2) = CONSTS(1)*CONSTS(2)*log( CONSTS(12)*STATES(2)) ALGBRC(6) = ALGBRC(2)+CONSTS(39) ALGBRC(7) = CONSTS(18)*(EXP(ALGBRC(5)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(6)/( CONSTS(1)*CONSTS(2)))) ALGBRC(8) = ALGBRC(2)+CONSTS(42) ALGBRC(3) = CONSTS(1)*CONSTS(2)*log( CONSTS(14)*STATES(3)) ALGBRC(9) = ALGBRC(3)+CONSTS(36) ALGBRC(10) = CONSTS(19)*(EXP(ALGBRC(8)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(9)/( CONSTS(1)*CONSTS(2)))) ALGBRC(11) = ALGBRC(7) - ALGBRC(10) RATES(2) = ALGBRC(11) ALGBRC(12) = ALGBRC(3)+CONSTS(45) ALGBRC(4) = CONSTS(1)*CONSTS(2)*log( CONSTS(16)*STATES(4)) ALGBRC(13) = ALGBRC(4)+CONSTS(51) ALGBRC(14) = CONSTS(20)*(EXP(ALGBRC(12)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(13)/( CONSTS(1)*CONSTS(2)))) ALGBRC(15) = ALGBRC(10) - ALGBRC(14) RATES(3) = ALGBRC(15) ALGBRC(16) = ALGBRC(4) ALGBRC(17) = ALGBRC(1)+CONSTS(48) ALGBRC(18) = CONSTS(21)*(EXP(ALGBRC(16)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(17)/( CONSTS(1)*CONSTS(2)))) ALGBRC(19) = ALGBRC(18) - ALGBRC(7) RATES(1) = ALGBRC(19) ALGBRC(20) = ALGBRC(14) - ALGBRC(18) RATES(4) = ALGBRC(20) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(1) = CONSTS(1)*CONSTS(2)*log( CONSTS(10)*STATES(1)) ALGBRC(5) = ALGBRC(1)+CONSTS(33) ALGBRC(2) = CONSTS(1)*CONSTS(2)*log( CONSTS(12)*STATES(2)) ALGBRC(6) = ALGBRC(2)+CONSTS(39) ALGBRC(7) = CONSTS(18)*(EXP(ALGBRC(5)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(6)/( CONSTS(1)*CONSTS(2)))) ALGBRC(8) = ALGBRC(2)+CONSTS(42) ALGBRC(3) = CONSTS(1)*CONSTS(2)*log( CONSTS(14)*STATES(3)) ALGBRC(9) = ALGBRC(3)+CONSTS(36) ALGBRC(10) = CONSTS(19)*(EXP(ALGBRC(8)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(9)/( CONSTS(1)*CONSTS(2)))) ALGBRC(11) = ALGBRC(7) - ALGBRC(10) ALGBRC(12) = ALGBRC(3)+CONSTS(45) ALGBRC(4) = CONSTS(1)*CONSTS(2)*log( CONSTS(16)*STATES(4)) ALGBRC(13) = ALGBRC(4)+CONSTS(51) ALGBRC(14) = CONSTS(20)*(EXP(ALGBRC(12)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(13)/( CONSTS(1)*CONSTS(2)))) ALGBRC(15) = ALGBRC(10) - ALGBRC(14) ALGBRC(16) = ALGBRC(4) ALGBRC(17) = ALGBRC(1)+CONSTS(48) ALGBRC(18) = CONSTS(21)*(EXP(ALGBRC(16)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(17)/( CONSTS(1)*CONSTS(2)))) ALGBRC(19) = ALGBRC(18) - ALGBRC(7) ALGBRC(20) = ALGBRC(14) - ALGBRC(18) RETURN END