Generated Code

The following is c code generated by the CellML API from this CellML file. (Back to language selection)

The raw code is available. 

/*
   There are a total of 36 entries in the algebraic variable array.
   There are a total of 14 entries in each of the rate and state variable arrays.
   There are a total of 39 entries in the constant variable array.
 */
/*
 * VOI is time in component environment (second).
 * CONSTANTS[0] is q_cAMP_init in component environment (fmol).
 * CONSTANTS[1] is q_PKI_init in component environment (fmol).
 * CONSTANTS[2] is q_PKACI_init in component environment (fmol).
 * CONSTANTS[3] is q_ARCI_init in component environment (fmol).
 * CONSTANTS[4] is q_A2RCI_init in component environment (fmol).
 * CONSTANTS[5] is q_CI_init in component environment (fmol).
 * CONSTANTS[6] is q_A2RI_init in component environment (fmol).
 * CONSTANTS[7] is q_PKACI_PKI_init in component environment (fmol).
 * CONSTANTS[8] is q_PKACII_init in component environment (fmol).
 * CONSTANTS[9] is q_ARCII_init in component environment (fmol).
 * CONSTANTS[10] is q_A2RCII_init in component environment (fmol).
 * CONSTANTS[11] is q_CII_init in component environment (fmol).
 * CONSTANTS[12] is q_A2RII_init in component environment (fmol).
 * CONSTANTS[13] is q_PKACII_PKI_init in component environment (fmol).
 * ALGEBRAIC[0] is q_cAMP in component environment (fmol).
 * ALGEBRAIC[1] is q_PKI in component environment (fmol).
 * ALGEBRAIC[2] is q_PKACI in component environment (fmol).
 * ALGEBRAIC[3] is q_ARCI in component environment (fmol).
 * ALGEBRAIC[4] is q_A2RCI in component environment (fmol).
 * ALGEBRAIC[5] is q_CI in component environment (fmol).
 * ALGEBRAIC[6] is q_A2RI in component environment (fmol).
 * ALGEBRAIC[7] is q_PKACI_PKI in component environment (fmol).
 * ALGEBRAIC[8] is q_PKACII in component environment (fmol).
 * ALGEBRAIC[9] is q_ARCII in component environment (fmol).
 * ALGEBRAIC[10] is q_A2RCII in component environment (fmol).
 * ALGEBRAIC[11] is q_CII in component environment (fmol).
 * ALGEBRAIC[12] is q_A2RII in component environment (fmol).
 * ALGEBRAIC[13] is q_PKACII_PKI in component environment (fmol).
 * STATES[0] is q_cAMP in component PKA (fmol).
 * STATES[1] is q_PKI in component PKA (fmol).
 * STATES[2] is q_PKACI in component PKA (fmol).
 * STATES[3] is q_ARCI in component PKA (fmol).
 * STATES[4] is q_A2RCI in component PKA (fmol).
 * STATES[5] is q_CI in component PKA (fmol).
 * STATES[6] is q_A2RI in component PKA (fmol).
 * STATES[7] is q_PKACI_PKI in component PKA (fmol).
 * STATES[8] is q_PKACII in component PKA (fmol).
 * STATES[9] is q_ARCII in component PKA (fmol).
 * STATES[10] is q_A2RCII in component PKA (fmol).
 * STATES[11] is q_CII in component PKA (fmol).
 * STATES[12] is q_A2RII in component PKA (fmol).
 * STATES[13] is q_PKACII_PKI in component PKA (fmol).
 * CONSTANTS[14] is kappa_aI in component PKA_parameters (fmol_per_sec).
 * CONSTANTS[15] is kappa_bI in component PKA_parameters (fmol_per_sec).
 * CONSTANTS[16] is kappa_dI in component PKA_parameters (fmol_per_sec).
 * CONSTANTS[17] is kappa_iI in component PKA_parameters (fmol_per_sec).
 * CONSTANTS[18] is kappa_aII in component PKA_parameters (fmol_per_sec).
 * CONSTANTS[19] is kappa_bII in component PKA_parameters (fmol_per_sec).
 * CONSTANTS[20] is kappa_dII in component PKA_parameters (fmol_per_sec).
 * CONSTANTS[21] is kappa_iII in component PKA_parameters (fmol_per_sec).
 * CONSTANTS[22] is K_cAMP in component PKA_parameters (per_fmol).
 * CONSTANTS[23] is K_PKI in component PKA_parameters (per_fmol).
 * CONSTANTS[24] is K_PKACI in component PKA_parameters (per_fmol).
 * CONSTANTS[25] is K_ARCI in component PKA_parameters (per_fmol).
 * CONSTANTS[26] is K_A2RCI in component PKA_parameters (per_fmol).
 * CONSTANTS[27] is K_CI in component PKA_parameters (per_fmol).
 * CONSTANTS[28] is K_A2RI in component PKA_parameters (per_fmol).
 * CONSTANTS[29] is K_PKACI_PKI in component PKA_parameters (per_fmol).
 * CONSTANTS[30] is K_PKACII in component PKA_parameters (per_fmol).
 * CONSTANTS[31] is K_ARCII in component PKA_parameters (per_fmol).
 * CONSTANTS[32] is K_A2RCII in component PKA_parameters (per_fmol).
 * CONSTANTS[33] is K_CII in component PKA_parameters (per_fmol).
 * CONSTANTS[34] is K_A2RII in component PKA_parameters (per_fmol).
 * CONSTANTS[35] is K_PKACII_PKI in component PKA_parameters (per_fmol).
 * CONSTANTS[36] is R in component constants (J_per_K_per_mol).
 * CONSTANTS[37] is T in component constants (kelvin).
 * ALGEBRAIC[28] is vaI in component PKA (fmol_per_sec).
 * ALGEBRAIC[29] is vbI in component PKA (fmol_per_sec).
 * ALGEBRAIC[30] is vdI in component PKA (fmol_per_sec).
 * ALGEBRAIC[31] is viI in component PKA (fmol_per_sec).
 * ALGEBRAIC[32] is vaII in component PKA (fmol_per_sec).
 * ALGEBRAIC[33] is vbII in component PKA (fmol_per_sec).
 * ALGEBRAIC[34] is vdII in component PKA (fmol_per_sec).
 * ALGEBRAIC[35] is viII in component PKA (fmol_per_sec).
 * ALGEBRAIC[14] is mu_cAMP in component PKA (J_per_mol).
 * ALGEBRAIC[15] is mu_PKI in component PKA (J_per_mol).
 * ALGEBRAIC[16] is mu_PKACI in component PKA (J_per_mol).
 * ALGEBRAIC[17] is mu_ARCI in component PKA (J_per_mol).
 * ALGEBRAIC[18] is mu_A2RCI in component PKA (J_per_mol).
 * ALGEBRAIC[19] is mu_CI in component PKA (J_per_mol).
 * ALGEBRAIC[20] is mu_A2RI in component PKA (J_per_mol).
 * ALGEBRAIC[21] is mu_PKACI_PKI in component PKA (J_per_mol).
 * ALGEBRAIC[22] is mu_PKACII in component PKA (J_per_mol).
 * ALGEBRAIC[23] is mu_ARCII in component PKA (J_per_mol).
 * ALGEBRAIC[24] is mu_A2RCII in component PKA (J_per_mol).
 * ALGEBRAIC[25] is mu_CII in component PKA (J_per_mol).
 * ALGEBRAIC[26] is mu_A2RII in component PKA (J_per_mol).
 * ALGEBRAIC[27] is mu_PKACII_PKI in component PKA (J_per_mol).
 * CONSTANTS[38] is F in component constants (C_per_mol).
 * RATES[0] is d/dt q_cAMP in component PKA (fmol).
 * RATES[1] is d/dt q_PKI in component PKA (fmol).
 * RATES[2] is d/dt q_PKACI in component PKA (fmol).
 * RATES[3] is d/dt q_ARCI in component PKA (fmol).
 * RATES[4] is d/dt q_A2RCI in component PKA (fmol).
 * RATES[5] is d/dt q_CI in component PKA (fmol).
 * RATES[6] is d/dt q_A2RI in component PKA (fmol).
 * RATES[7] is d/dt q_PKACI_PKI in component PKA (fmol).
 * RATES[8] is d/dt q_PKACII in component PKA (fmol).
 * RATES[9] is d/dt q_ARCII in component PKA (fmol).
 * RATES[10] is d/dt q_A2RCII in component PKA (fmol).
 * RATES[11] is d/dt q_CII in component PKA (fmol).
 * RATES[12] is d/dt q_A2RII in component PKA (fmol).
 * RATES[13] is d/dt q_PKACII_PKI in component PKA (fmol).
 */
void
initConsts(double* CONSTANTS, double* RATES, double *STATES)
{
CONSTANTS[0] = 3.212E-02;
CONSTANTS[1] = 6.840E-03;
CONSTANTS[2] = 2.242E-02;
CONSTANTS[3] = 3.800E-15;
CONSTANTS[4] = 3.800E-15;
CONSTANTS[5] = 3.800E-15;
CONSTANTS[6] = 3.800E-15;
CONSTANTS[7] = 3.800E-15;
CONSTANTS[8] = 9.500E-04;
CONSTANTS[9] = 3.800E-15;
CONSTANTS[10] = 3.800E-15;
CONSTANTS[11] = 3.800E-15;
CONSTANTS[12] = 3.800E-15;
CONSTANTS[13] = 3.800E-15;
STATES[0] = 1e-16;
STATES[1] = 1e-16;
STATES[2] = 1e-16;
STATES[3] = 1e-16;
STATES[4] = 1e-16;
STATES[5] = 1e-16;
STATES[6] = 1e-16;
STATES[7] = 1e-16;
STATES[8] = 1e-16;
STATES[9] = 1e-16;
STATES[10] = 1e-16;
STATES[11] = 1e-16;
STATES[12] = 1e-16;
STATES[13] = 1e-16;
CONSTANTS[14] = 48.0417;
CONSTANTS[15] = 21.1895;
CONSTANTS[16] = 4.84331;
CONSTANTS[17] = 149.139;
CONSTANTS[18] = 48.0417;
CONSTANTS[19] = 21.1895;
CONSTANTS[20] = 4.84331;
CONSTANTS[21] = 149.139;
CONSTANTS[22] = 0.0401879;
CONSTANTS[23] = 14.3814;
CONSTANTS[24] = 0.0478876;
CONSTANTS[25] = 0.605095;
CONSTANTS[26] = 1.3719;
CONSTANTS[27] = 1.96997;
CONSTANTS[28] = 0.0885687;
CONSTANTS[29] = 0.194918;
CONSTANTS[30] = 0.0478876;
CONSTANTS[31] = 0.605095;
CONSTANTS[32] = 1.3719;
CONSTANTS[33] = 1.96997;
CONSTANTS[34] = 0.0885687;
CONSTANTS[35] = 0.194918;
CONSTANTS[36] = 8.31;
CONSTANTS[37] = 310;
CONSTANTS[38] = 96485;
}
void
computeRates(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[0] = STATES[0]+CONSTANTS[0];
ALGEBRAIC[14] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[22]*ALGEBRAIC[0]);
ALGEBRAIC[2] = STATES[2]+CONSTANTS[2];
ALGEBRAIC[16] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[24]*ALGEBRAIC[2]);
ALGEBRAIC[3] = STATES[3]+CONSTANTS[3];
ALGEBRAIC[17] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[25]*ALGEBRAIC[3]);
ALGEBRAIC[28] =  CONSTANTS[14]*(exp((ALGEBRAIC[16]+ALGEBRAIC[14])/( CONSTANTS[36]*CONSTANTS[37])) - exp(ALGEBRAIC[17]/( CONSTANTS[36]*CONSTANTS[37])));
RATES[2] = - ALGEBRAIC[28];
ALGEBRAIC[4] = STATES[4]+CONSTANTS[4];
ALGEBRAIC[18] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[26]*ALGEBRAIC[4]);
ALGEBRAIC[29] =  CONSTANTS[15]*(exp((ALGEBRAIC[17]+ALGEBRAIC[14])/( CONSTANTS[36]*CONSTANTS[37])) - exp(ALGEBRAIC[18]/( CONSTANTS[36]*CONSTANTS[37])));
RATES[3] = ALGEBRAIC[28] - ALGEBRAIC[29];
ALGEBRAIC[5] = STATES[5]+CONSTANTS[5];
ALGEBRAIC[19] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[27]*ALGEBRAIC[5]);
ALGEBRAIC[6] = STATES[6]+CONSTANTS[6];
ALGEBRAIC[20] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[28]*ALGEBRAIC[6]);
ALGEBRAIC[30] =  CONSTANTS[16]*(exp(ALGEBRAIC[18]/( CONSTANTS[36]*CONSTANTS[37])) - exp((ALGEBRAIC[20]+ALGEBRAIC[19])/( CONSTANTS[36]*CONSTANTS[37])));
RATES[4] = ALGEBRAIC[29] - ALGEBRAIC[30];
RATES[6] = ALGEBRAIC[30];
ALGEBRAIC[1] = STATES[1]+CONSTANTS[1];
ALGEBRAIC[15] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[23]*ALGEBRAIC[1]);
ALGEBRAIC[7] = STATES[7]+CONSTANTS[7];
ALGEBRAIC[21] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[29]*ALGEBRAIC[7]);
ALGEBRAIC[31] =  CONSTANTS[17]*(exp((ALGEBRAIC[19]+ALGEBRAIC[15])/( CONSTANTS[36]*CONSTANTS[37])) - exp(ALGEBRAIC[21]/( CONSTANTS[36]*CONSTANTS[37])));
RATES[5] = ALGEBRAIC[30] - ALGEBRAIC[31];
RATES[7] = ALGEBRAIC[31];
ALGEBRAIC[8] = STATES[8]+CONSTANTS[8];
ALGEBRAIC[22] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[30]*ALGEBRAIC[8]);
ALGEBRAIC[9] = STATES[9]+CONSTANTS[9];
ALGEBRAIC[23] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[31]*ALGEBRAIC[9]);
ALGEBRAIC[32] =  CONSTANTS[18]*(exp((ALGEBRAIC[22]+ALGEBRAIC[14])/( CONSTANTS[36]*CONSTANTS[37])) - exp(ALGEBRAIC[23]/( CONSTANTS[36]*CONSTANTS[37])));
RATES[8] = - ALGEBRAIC[32];
ALGEBRAIC[10] = STATES[10]+CONSTANTS[10];
ALGEBRAIC[24] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[32]*ALGEBRAIC[10]);
ALGEBRAIC[33] =  CONSTANTS[19]*(exp((ALGEBRAIC[23]+ALGEBRAIC[14])/( CONSTANTS[36]*CONSTANTS[37])) - exp(ALGEBRAIC[24]/( CONSTANTS[36]*CONSTANTS[37])));
RATES[0] = ((- ALGEBRAIC[28] - ALGEBRAIC[29]) - ALGEBRAIC[32]) - ALGEBRAIC[33];
RATES[9] = ALGEBRAIC[32] - ALGEBRAIC[33];
ALGEBRAIC[11] = STATES[11]+CONSTANTS[11];
ALGEBRAIC[25] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[33]*ALGEBRAIC[11]);
ALGEBRAIC[12] = STATES[12]+CONSTANTS[12];
ALGEBRAIC[26] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[34]*ALGEBRAIC[12]);
ALGEBRAIC[34] =  CONSTANTS[20]*(exp(ALGEBRAIC[24]/( CONSTANTS[36]*CONSTANTS[37])) - exp((ALGEBRAIC[26]+ALGEBRAIC[25])/( CONSTANTS[36]*CONSTANTS[37])));
RATES[10] = ALGEBRAIC[33] - ALGEBRAIC[34];
RATES[12] = ALGEBRAIC[34];
ALGEBRAIC[13] = STATES[13]+CONSTANTS[13];
ALGEBRAIC[27] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[35]*ALGEBRAIC[13]);
ALGEBRAIC[35] =  CONSTANTS[21]*(exp((ALGEBRAIC[25]+ALGEBRAIC[15])/( CONSTANTS[36]*CONSTANTS[37])) - exp(ALGEBRAIC[27]/( CONSTANTS[36]*CONSTANTS[37])));
RATES[1] = - ALGEBRAIC[31] - ALGEBRAIC[35];
RATES[11] = ALGEBRAIC[34] - ALGEBRAIC[35];
RATES[13] = ALGEBRAIC[35];
}
void
computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[0] = STATES[0]+CONSTANTS[0];
ALGEBRAIC[14] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[22]*ALGEBRAIC[0]);
ALGEBRAIC[2] = STATES[2]+CONSTANTS[2];
ALGEBRAIC[16] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[24]*ALGEBRAIC[2]);
ALGEBRAIC[3] = STATES[3]+CONSTANTS[3];
ALGEBRAIC[17] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[25]*ALGEBRAIC[3]);
ALGEBRAIC[28] =  CONSTANTS[14]*(exp((ALGEBRAIC[16]+ALGEBRAIC[14])/( CONSTANTS[36]*CONSTANTS[37])) - exp(ALGEBRAIC[17]/( CONSTANTS[36]*CONSTANTS[37])));
ALGEBRAIC[4] = STATES[4]+CONSTANTS[4];
ALGEBRAIC[18] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[26]*ALGEBRAIC[4]);
ALGEBRAIC[29] =  CONSTANTS[15]*(exp((ALGEBRAIC[17]+ALGEBRAIC[14])/( CONSTANTS[36]*CONSTANTS[37])) - exp(ALGEBRAIC[18]/( CONSTANTS[36]*CONSTANTS[37])));
ALGEBRAIC[5] = STATES[5]+CONSTANTS[5];
ALGEBRAIC[19] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[27]*ALGEBRAIC[5]);
ALGEBRAIC[6] = STATES[6]+CONSTANTS[6];
ALGEBRAIC[20] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[28]*ALGEBRAIC[6]);
ALGEBRAIC[30] =  CONSTANTS[16]*(exp(ALGEBRAIC[18]/( CONSTANTS[36]*CONSTANTS[37])) - exp((ALGEBRAIC[20]+ALGEBRAIC[19])/( CONSTANTS[36]*CONSTANTS[37])));
ALGEBRAIC[1] = STATES[1]+CONSTANTS[1];
ALGEBRAIC[15] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[23]*ALGEBRAIC[1]);
ALGEBRAIC[7] = STATES[7]+CONSTANTS[7];
ALGEBRAIC[21] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[29]*ALGEBRAIC[7]);
ALGEBRAIC[31] =  CONSTANTS[17]*(exp((ALGEBRAIC[19]+ALGEBRAIC[15])/( CONSTANTS[36]*CONSTANTS[37])) - exp(ALGEBRAIC[21]/( CONSTANTS[36]*CONSTANTS[37])));
ALGEBRAIC[8] = STATES[8]+CONSTANTS[8];
ALGEBRAIC[22] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[30]*ALGEBRAIC[8]);
ALGEBRAIC[9] = STATES[9]+CONSTANTS[9];
ALGEBRAIC[23] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[31]*ALGEBRAIC[9]);
ALGEBRAIC[32] =  CONSTANTS[18]*(exp((ALGEBRAIC[22]+ALGEBRAIC[14])/( CONSTANTS[36]*CONSTANTS[37])) - exp(ALGEBRAIC[23]/( CONSTANTS[36]*CONSTANTS[37])));
ALGEBRAIC[10] = STATES[10]+CONSTANTS[10];
ALGEBRAIC[24] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[32]*ALGEBRAIC[10]);
ALGEBRAIC[33] =  CONSTANTS[19]*(exp((ALGEBRAIC[23]+ALGEBRAIC[14])/( CONSTANTS[36]*CONSTANTS[37])) - exp(ALGEBRAIC[24]/( CONSTANTS[36]*CONSTANTS[37])));
ALGEBRAIC[11] = STATES[11]+CONSTANTS[11];
ALGEBRAIC[25] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[33]*ALGEBRAIC[11]);
ALGEBRAIC[12] = STATES[12]+CONSTANTS[12];
ALGEBRAIC[26] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[34]*ALGEBRAIC[12]);
ALGEBRAIC[34] =  CONSTANTS[20]*(exp(ALGEBRAIC[24]/( CONSTANTS[36]*CONSTANTS[37])) - exp((ALGEBRAIC[26]+ALGEBRAIC[25])/( CONSTANTS[36]*CONSTANTS[37])));
ALGEBRAIC[13] = STATES[13]+CONSTANTS[13];
ALGEBRAIC[27] =  CONSTANTS[36]*CONSTANTS[37]*log( CONSTANTS[35]*ALGEBRAIC[13]);
ALGEBRAIC[35] =  CONSTANTS[21]*(exp((ALGEBRAIC[25]+ALGEBRAIC[15])/( CONSTANTS[36]*CONSTANTS[37])) - exp(ALGEBRAIC[27]/( CONSTANTS[36]*CONSTANTS[37])));
}
Source
Derived from workspace BG_PKA at changeset 0ce0d5718635.
Collaboration
To begin collaborating on this work, please use your git client and issue this command:
License
The terms of use/license for this work is unspecified.