C C There are a total of 13 entries in the algebraic variable array. C There are a total of 4 entries in each of the rate and state variable arrays. C There are a total of 29 entries in the constant variable array. C C C STATES(1) is P_Open in component kinetics (dimensionless). C STATES(2) is P_Closed in component kinetics (dimensionless). C STATES(3) is P_I1 in component kinetics (dimensionless). C STATES(4) is P_I2 in component kinetics (dimensionless). C VOI is time in component environment (ms). C ALGBRC(3) is current in component stimulus_protocol (nA_per_nF). C ALGBRC(4) is voltage_out in component environment (mV). C ALGBRC(5) is transmembranevoltage in component environment (mV). C ALGBRC(2) is pressure in component environment (mmHg). C ALGBRC(1) is stretch in component stimulus_protocol (dimensionless). C CONSTS(1) is pressure_stim_offset in component environment (ms). C CONSTS(2) is pressure_stim_period in component environment (ms). C CONSTS(3) is pressure_stim_duration in component environment (ms). C CONSTS(4) is pressure_stim_amplitude in component environment (dimensionless). C CONSTS(5) is current_stim_offset in component environment (ms). C CONSTS(6) is current_stim_period in component environment (ms). C CONSTS(7) is current_stim_duration in component environment (ms). C CONSTS(8) is current_stim_amplitude in component environment (nA_per_nF). C CONSTS(9) is current_stim_end in component environment (ms). C CONSTS(10) is current_N_period_total in component environment (dimensionless). C CONSTS(11) is current_N_period_applied in component environment (dimensionless). C CONSTS(12) is r1 in component kinetics (per_ms). C CONSTS(13) is r3 in component kinetics (per_ms). C CONSTS(14) is r4 in component kinetics (per_ms). C CONSTS(15) is r5 in component kinetics (per_ms). C CONSTS(16) is r6 in component kinetics (per_ms). C CONSTS(17) is r7 in component kinetics (per_ms). C CONSTS(18) is r8 in component kinetics (per_ms). C CONSTS(19) is ce1 in component kinetics (dimensionless). C CONSTS(20) is ce3 in component kinetics (dimensionless). C CONSTS(21) is ce4 in component kinetics (dimensionless). C CONSTS(22) is cm4 in component kinetics (dimensionless). C CONSTS(23) is ce5 in component kinetics (dimensionless). C CONSTS(24) is ce6 in component kinetics (dimensionless). C CONSTS(25) is ce7 in component kinetics (dimensionless). C CONSTS(26) is ce8 in component kinetics (dimensionless). C CONSTS(27) is r2 in component kinetics (per_ms). C CONSTS(28) is ce2 in component kinetics (dimensionless). C CONSTS(29) is cm2 in component kinetics (dimensionless). C ALGBRC(6) is p_O_I1 in component kinetics (per_ms). C ALGBRC(7) is p_I1_O in component kinetics (per_ms). C ALGBRC(8) is p_I1_C in component kinetics (per_ms). C ALGBRC(9) is p_C_I1 in component kinetics (per_ms). C ALGBRC(10) is p_C_O in component kinetics (per_ms). C ALGBRC(11) is p_O_C in component kinetics (per_ms). C ALGBRC(12) is p_I2_O in component kinetics (per_ms). C ALGBRC(13) is p_O_I2 in component kinetics (per_ms). C RATES(1) is d/dt P_Open in component kinetics (dimensionless). C RATES(2) is d/dt P_Closed in component kinetics (dimensionless). C RATES(3) is d/dt P_I1 in component kinetics (dimensionless). C RATES(4) is d/dt P_I2 in component kinetics (dimensionless). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) STATES(1) = 0.0 STATES(2) = 0.3 STATES(3) = 0.1 STATES(4) = 0.6 CONSTS(1) = 100 CONSTS(2) = 2000 CONSTS(3) = 5 CONSTS(4) = 1.1 CONSTS(5) = 100 CONSTS(6) = 1000 CONSTS(7) = 500 CONSTS(8) = 80 CONSTS(9) = 999999999999999 CONSTS(10) = 1 CONSTS(11) = 1 CONSTS(12) = 0.02634342 CONSTS(13) = 0.0008000712 CONSTS(14) = 0.008945307 CONSTS(15) = 1.3529515e-5 CONSTS(16) = 6.206403e-5 CONSTS(17) = 6.603723e-6 CONSTS(18) = 0.00079357607 CONSTS(19) = -2.3753126 CONSTS(20) = -5.6010337 CONSTS(21) = 0.70629007 CONSTS(22) = -12.101605 CONSTS(23) = 6.46389 CONSTS(24) = -1.2173947 CONSTS(25) = 8.739162 CONSTS(26) = -3.364573 CONSTS(27) = ( CONSTS(12)*CONSTS(13)*CONSTS(15))/( CONSTS(14)*CONSTS(16)) CONSTS(28) = ((CONSTS(19)+CONSTS(20)+CONSTS(23)) - CONSTS(21)) - CONSTS(24) CONSTS(29) = - CONSTS(22) RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(3) = TERNRY(VOI.GE.CONSTS(5).AND.VOI.LT.CONSTS(9).AND. INT(MOD(VOI - CONSTS(5), CONSTS(6))).LE.CONSTS(7).AND. INT(MOD(VOI - CONSTS(5), CONSTS(10)*CONSTS(6))).LT. CONSTS(11)*CONSTS(6), CONSTS(8), 0.00000) ALGBRC(4) = (ALGBRC(3)/1.00000)*1.00000 ALGBRC(6) = CONSTS(12)*EXP(( CONSTS(19)*ALGBRC(4))/140.000) ALGBRC(1) = TERNRY(VOI.GE.CONSTS(1).AND. INT(MOD(VOI - CONSTS(1), CONSTS(2))).LE.CONSTS(3), CONSTS(4), 1.00000) ALGBRC(2) = 350.000*MAX(2, 0.00000, ALGBRC(1) - 1.00000) ALGBRC(7) = CONSTS(27)*EXP(( CONSTS(28)*ALGBRC(4))/140.000+( CONSTS(29)*ALGBRC(2))/70.0000) ALGBRC(8) = CONSTS(13)*EXP(( CONSTS(20)*ALGBRC(4))/140.000) ALGBRC(9) = CONSTS(14)*EXP(( CONSTS(21)*ALGBRC(4))/140.000+( CONSTS(22)*ALGBRC(2))/70.0000) RATES(3) = - (ALGBRC(7)+ALGBRC(8))*STATES(3)+ ALGBRC(9)*STATES(2)+ ALGBRC(6)*STATES(1) ALGBRC(10) = CONSTS(15)*EXP(( CONSTS(23)*ALGBRC(4))/140.000) ALGBRC(11) = CONSTS(16)*EXP(( CONSTS(24)*ALGBRC(4))/140.000) RATES(2) = - (ALGBRC(9)+ALGBRC(10))*STATES(2)+ ALGBRC(11)*STATES(1)+ ALGBRC(8)*STATES(3) ALGBRC(12) = CONSTS(17)*EXP(( (( CONSTS(25)*ALGBRC(4))/140.000)*ALGBRC(2))/70.0000) ALGBRC(13) = CONSTS(18)*EXP(( CONSTS(26)*ALGBRC(4))/140.000) RATES(1) = - (ALGBRC(6)+ALGBRC(13)+ALGBRC(11))*STATES(1)+ ALGBRC(10)*STATES(2)+ ALGBRC(7)*STATES(3)+ ALGBRC(12)*STATES(4) RATES(4) = - ALGBRC(12)*STATES(4)+ ALGBRC(13)*STATES(1) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(3) = TERNRY(VOI.GE.CONSTS(5).AND.VOI.LT.CONSTS(9).AND. INT(MOD(VOI - CONSTS(5), CONSTS(6))).LE.CONSTS(7).AND. INT(MOD(VOI - CONSTS(5), CONSTS(10)*CONSTS(6))).LT. CONSTS(11)*CONSTS(6), CONSTS(8), 0.00000) ALGBRC(4) = (ALGBRC(3)/1.00000)*1.00000 ALGBRC(6) = CONSTS(12)*EXP(( CONSTS(19)*ALGBRC(4))/140.000) ALGBRC(1) = TERNRY(VOI.GE.CONSTS(1).AND. INT(MOD(VOI - CONSTS(1), CONSTS(2))).LE.CONSTS(3), CONSTS(4), 1.00000) ALGBRC(2) = 350.000*MAX(2, 0.00000, ALGBRC(1) - 1.00000) ALGBRC(7) = CONSTS(27)*EXP(( CONSTS(28)*ALGBRC(4))/140.000+( CONSTS(29)*ALGBRC(2))/70.0000) ALGBRC(8) = CONSTS(13)*EXP(( CONSTS(20)*ALGBRC(4))/140.000) ALGBRC(9) = CONSTS(14)*EXP(( CONSTS(21)*ALGBRC(4))/140.000+( CONSTS(22)*ALGBRC(2))/70.0000) ALGBRC(10) = CONSTS(15)*EXP(( CONSTS(23)*ALGBRC(4))/140.000) ALGBRC(11) = CONSTS(16)*EXP(( CONSTS(24)*ALGBRC(4))/140.000) ALGBRC(12) = CONSTS(17)*EXP(( (( CONSTS(25)*ALGBRC(4))/140.000)*ALGBRC(2))/70.0000) ALGBRC(13) = CONSTS(18)*EXP(( CONSTS(26)*ALGBRC(4))/140.000) ALGBRC(5) = (ALGBRC(4) - 5.00000)*STATES(1) RETURN END REAL FUNCTION TERNRY(TEST, VALA, VALB) LOGICAL TEST REAL VALA, VALB IF (TEST) THEN TERNRY = VALA ELSE TERNRY = VALB ENDIF RETURN END