Noble, Denyer, Brown, DiFrancesco, 1992

This exposure contains a CellML version of the Noble, Denyer, Brown & DiFrancesco model (1992).

Relevant files

noble_denyer_brown_difrancesco_1992.cellml: CellML version of the model.
noble_denyer_brown_difrancesco_1992.sedml: SED-ML file for simulating the model.
simulation.json: JSON file for use with Web OpenCOR's interactive mode.
manifest.xml: manifest file used by PMR to create a crafted COMBINE archive.

Usage

The easiest way to use this model is by:

switching to the CellML view (alternatively, by clicking on the noble_denyer_brown_difrancesco_1992.cellml link to the right of this page under the Navigation section);
starting legacy OpenCOR or opening Web OpenCOR;
right clicking on the COMBINE Archive (crafted) button (to the right of this page under the Downloads section);
selecting Copy Link Address (or similar, depending on your Web browser); and
opening the copied link in legacy OpenCOR or Web OpenCOR (using the File | Open Remote... menu).

Noble, Denyer, Brown & DiFrancesco model (1992)

Citation

Noble D, Denyer JC, Brown HF, DiFrancesco D. Reciprocal role of the inward currents i_b,Na and i_f in controlling and stabilizing pacemaker frequency of rabbit sino-atrial node cells. Proc Biol Sci. 1992 Dec 22;250(1329):199-207. doi: 10.1098/rspb.1992.0150. PMID: 1283636.