Generated Code
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C
C There are a total of 2 entries in the algebraic variable array.
C There are a total of 9 entries in each of the rate and state variable arrays.
C There are a total of 30 entries in the constant variable array.
C
C
C VOI is time in component environment (hour).
C CONSTS(30) is F_c in component gastrointestinal_compartment_L_dopa (dimensionless).
C STATES(1) is A_dopa_c in component gastrointestinal_compartment_L_dopa (umole).
C CONSTS(1) is ka_c in component gastrointestinal_compartment_L_dopa (per_hour).
C CONSTS(22) is F_G in component gastrointestinal_compartment_L_dopa (dimensionless).
C CONSTS(29) is F_H in component gastrointestinal_compartment_L_dopa (dimensionless).
C CONSTS(26) is CL_H in component gastrointestinal_compartment_L_dopa (liter_per_hour).
C CONSTS(2) is Q in component gastrointestinal_compartment_L_dopa (liter_per_hour).
C CONSTS(3) is f_H in component gastrointestinal_compartment_L_dopa (dimensionless).
C CONSTS(4) is CL_dopa_0 in component L_dopa_clearance (liter_per_hour).
C STATES(2) is C_dopa_c in component body_compartment_L_dopa (uM).
C CONSTS(5) is V_dopa in component body_compartment_L_dopa (liter).
C ALGBRC(2) is CL_dopa in component L_dopa_clearance (liter_per_hour).
C STATES(3) is C_OMD_c in component body_compartment_3_OMD (uM).
C CONSTS(6) is CL_OMD_c in component body_compartment_3_OMD (liter_per_hour).
C CONSTS(7) is V_OMD_c in component body_compartment_3_OMD (liter).
C CONSTS(23) is CL_COMT in component L_dopa_clearance (liter_per_hour).
C ALGBRC(1) is CL_AADC in component L_dopa_clearance (liter_per_hour).
C CONSTS(24) is CL_AADC0 in component L_dopa_clearance (liter_per_hour).
C STATES(4) is C_Ro_central in component central_compartment_Ro (uM).
C CONSTS(27) is CL_REST in component L_dopa_clearance (liter_per_hour).
C CONSTS(8) is ki in component L_dopa_clearance (uM).
C STATES(5) is A_bens in component gastrointestinal_compartment_benserazide (umole).
C CONSTS(9) is ka_B in component gastrointestinal_compartment_benserazide (per_hour).
C CONSTS(10) is F_B in component gastrointestinal_compartment_benserazide (dimensionless).
C STATES(6) is C_bens_central in component central_compartment_benserazide (uM).
C CONSTS(11) is V1_B in component central_compartment_benserazide (liter).
C CONSTS(12) is CLd_B in component central_compartment_benserazide (liter_per_hour).
C STATES(7) is C_bens_peripheral in component peripheral_compartment_benserazide (uM).
C CONSTS(25) is CL_bens_total in component benserazide_clearance (liter_per_hour).
C CONSTS(13) is V2_B in component peripheral_compartment_benserazide (liter).
C CONSTS(28) is CL_Ro in component benserazide_clearance (liter_per_hour).
C CONSTS(14) is CL_B in component benserazide_clearance (liter_per_hour).
C CONSTS(15) is fm in component benserazide_clearance (dimensionless).
C STATES(8) is A_Ro in component gastrointestinal_compartment_Ro (umole).
C CONSTS(16) is ka_M in component gastrointestinal_compartment_Ro (per_hour).
C CONSTS(17) is F_Ro in component gastrointestinal_compartment_Ro (dimensionless).
C CONSTS(18) is V1_M in component central_compartment_Ro (liter).
C CONSTS(19) is CLd_M in component central_compartment_Ro (liter_per_hour).
C CONSTS(20) is CL_M in component central_compartment_Ro (liter_per_hour).
C STATES(9) is C_Ro_peripheral in component peripheral_compartment_Ro (uM).
C CONSTS(21) is V2_M in component peripheral_compartment_Ro (liter).
C RATES(1) is d/dt A_dopa_c in component gastrointestinal_compartment_L_dopa (umole).
C RATES(2) is d/dt C_dopa_c in component body_compartment_L_dopa (uM).
C RATES(3) is d/dt C_OMD_c in component body_compartment_3_OMD (uM).
C RATES(5) is d/dt A_bens in component gastrointestinal_compartment_benserazide (umole).
C RATES(6) is d/dt C_bens_central in component central_compartment_benserazide (uM).
C RATES(7) is d/dt C_bens_peripheral in component peripheral_compartment_benserazide (uM).
C RATES(8) is d/dt A_Ro in component gastrointestinal_compartment_Ro (umole).
C RATES(4) is d/dt C_Ro_central in component central_compartment_Ro (uM).
C RATES(9) is d/dt C_Ro_peripheral in component peripheral_compartment_Ro (uM).
C
SUBROUTINE initConsts(CONSTS, RATES, STATES)
REAL CONSTS(*), RATES(*), STATES(*)
STATES(1) = 101
CONSTS(1) = 1.29
CONSTS(2) = 0.828
CONSTS(3) = 0.13
CONSTS(4) = 0.823
STATES(2) = 0
CONSTS(5) = 0.496
STATES(3) = 0
CONSTS(6) = 0.00895
CONSTS(7) = 0.128
STATES(4) = 0
CONSTS(8) = 0.00246
STATES(5) = 19.51
CONSTS(9) = 0.94
CONSTS(10) = 0.022
STATES(6) = 0
CONSTS(11) = 0.202
CONSTS(12) = 0.072
STATES(7) = 0
CONSTS(13) = 0.127
CONSTS(14) = 1.67
CONSTS(15) = 0.15
STATES(8) = 1.3658
CONSTS(16) = 2.47
CONSTS(17) = 1
CONSTS(18) = 0.0691
CONSTS(19) = 1.06
CONSTS(20) = 4.29
STATES(9) = 0
CONSTS(21) = 3.2
CONSTS(22) = 1.00000
CONSTS(23) = CONSTS(4)*0.100000
CONSTS(24) = CONSTS(4)*0.690000
CONSTS(25) = CONSTS(14)/(1.00000 - CONSTS(15))
CONSTS(26) = CONSTS(3)*CONSTS(4)
CONSTS(27) = CONSTS(4)*0.210000
CONSTS(28) = CONSTS(25)*CONSTS(15)
CONSTS(29) = 1.00000 - CONSTS(26)/CONSTS(2)
CONSTS(30) = CONSTS(29)*CONSTS(22)
RETURN
END
SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC)
REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*)
RATES(1) = - CONSTS(1)*STATES(1)
RATES(3) = (1.00000/CONSTS(7))*( CONSTS(23)*STATES(2) - CONSTS(6)*STATES(3))
RATES(5) = - CONSTS(9)*STATES(5)
RATES(6) = (1.00000/CONSTS(11))*(( CONSTS(9)*STATES(5)*CONSTS(10) - CONSTS(25)*STATES(6))+ CONSTS(12)*(STATES(7) - STATES(6)))
RATES(7) = (1.00000/CONSTS(13))*( CONSTS(12)*(STATES(6) - STATES(7)))
RATES(8) = - CONSTS(16)*STATES(8)
RATES(4) = (1.00000/CONSTS(18))*(( CONSTS(16)*STATES(8)*CONSTS(17) - CONSTS(20)*STATES(4))+ CONSTS(28)*STATES(6)+ CONSTS(19)*(STATES(9) - STATES(4)))
RATES(9) = (1.00000/CONSTS(21))*( CONSTS(19)*(STATES(4) - STATES(9)))
ALGBRC(1) = CONSTS(24)/(1.00000+STATES(4)/CONSTS(8))
ALGBRC(2) = ALGBRC(1)+CONSTS(23)+CONSTS(27)
RATES(2) = (1.00000/CONSTS(5))*( CONSTS(1)*STATES(1)*CONSTS(30) - ALGBRC(2)*STATES(2))
RETURN
END
SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC)
REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*)
ALGBRC(1) = CONSTS(24)/(1.00000+STATES(4)/CONSTS(8))
ALGBRC(2) = ALGBRC(1)+CONSTS(23)+CONSTS(27)
RETURN
END
