Generated Code
The following is c code generated by the CellML API from this CellML file. (Back to language selection)
The raw code is available.
/*
There are a total of 2 entries in the algebraic variable array.
There are a total of 34 entries in each of the rate and state variable arrays.
There are a total of 55 entries in the constant variable array.
*/
/*
* VOI is time in component environment (minute).
* STATES[0] is v_c in component v_c (nanomolar).
* ALGEBRAIC[0] is dv_c_dt in component dv_c_dt (flux).
* CONSTANTS[0] is k_growth in component rate_constants (first_order_rate_constant).
* STATES[1] is v_n in component v_n (nanomolar).
* ALGEBRAIC[1] is k_volume in component k_volume (dimensionless).
* STATES[2] is mcln2_c in component mcln2_c (nanomolar).
* CONSTANTS[1] is k_50 in component rate_constants (first_order_rate_constant).
* CONSTANTS[2] is k_10 in component rate_constants (first_order_rate_constant).
* STATES[3] is mcln2_n in component mcln2_n (nanomolar).
* STATES[4] is mclb5_c in component mclb5_c (nanomolar).
* CONSTANTS[3] is k_51 in component rate_constants (first_order_rate_constant).
* CONSTANTS[4] is k_11 in component rate_constants (first_order_rate_constant).
* STATES[5] is mclb5_n in component mclb5_n (nanomolar).
* CONSTANTS[5] is k_1 in component rate_constants (first_order_rate_constant).
* STATES[6] is sbf_n in component sbf_n (nanomolar).
* CONSTANTS[6] is k_2 in component rate_constants (first_order_rate_constant).
* CONSTANTS[7] is k_39 in component rate_constants (first_order_rate_constant).
* CONSTANTS[8] is k_34 in component rate_constants (second_order_rate_constant).
* CONSTANTS[9] is k_35 in component rate_constants (first_order_rate_constant).
* STATES[7] is sbfwhi5p_n in component sbfwhi5p_n (nanomolar).
* STATES[8] is whi5_n in component whi5_n (nanomolar).
* STATES[9] is sbfwhi5_n in component sbfwhi5_n (nanomolar).
* STATES[10] is cln3_c in component cln3_c (nanomolar).
* CONSTANTS[10] is k_6 in component rate_constants (flux).
* CONSTANTS[11] is k_43 in component rate_constants (first_order_rate_constant).
* CONSTANTS[12] is k_15 in component rate_constants (first_order_rate_constant).
* STATES[11] is cln2_c in component cln2_c (nanomolar).
* CONSTANTS[13] is k_3 in component rate_constants (first_order_rate_constant).
* CONSTANTS[14] is k_26 in component rate_constants (second_order_rate_constant).
* CONSTANTS[15] is k_27 in component rate_constants (first_order_rate_constant).
* CONSTANTS[16] is k_12 in component rate_constants (first_order_rate_constant).
* STATES[12] is cdk1_c in component cdk1_c (nanomolar).
* STATES[13] is cdk1cln2_c in component cdk1cln2_c (nanomolar).
* STATES[14] is clb5_c in component clb5_c (nanomolar).
* CONSTANTS[17] is k_4 in component rate_constants (first_order_rate_constant).
* CONSTANTS[18] is k_28 in component rate_constants (second_order_rate_constant).
* CONSTANTS[19] is k_29 in component rate_constants (first_order_rate_constant).
* CONSTANTS[20] is k_13 in component rate_constants (first_order_rate_constant).
* STATES[15] is cdk1clb5_c in component cdk1clb5_c (nanomolar).
* CONSTANTS[21] is k_7 in component rate_constants (flux).
* CONSTANTS[22] is k_44 in component rate_constants (first_order_rate_constant).
* CONSTANTS[23] is k_49 in component rate_constants (first_order_rate_constant).
* CONSTANTS[24] is k_16 in component rate_constants (first_order_rate_constant).
* STATES[16] is cdk1_n in component cdk1_n (nanomolar).
* STATES[17] is cln3_n in component cln3_n (nanomolar).
* CONSTANTS[25] is k_24 in component rate_constants (second_order_rate_constant).
* CONSTANTS[26] is k_25 in component rate_constants (first_order_rate_constant).
* CONSTANTS[27] is k_20 in component rate_constants (first_order_rate_constant).
* STATES[18] is cdk1cln3_n in component cdk1cln3_n (nanomolar).
* CONSTANTS[28] is k_21 in component rate_constants (first_order_rate_constant).
* CONSTANTS[29] is k_46 in component rate_constants (first_order_rate_constant).
* CONSTANTS[30] is k_53 in component rate_constants (first_order_rate_constant).
* STATES[19] is cdk1cln2_n in component cdk1cln2_n (nanomolar).
* CONSTANTS[31] is k_33 in component rate_constants (first_order_rate_constant).
* CONSTANTS[32] is k_32 in component rate_constants (second_order_rate_constant).
* CONSTANTS[33] is k_48 in component rate_constants (first_order_rate_constant).
* STATES[20] is cdk1clb5sic1_c in component cdk1clb5sic1_c (nanomolar).
* STATES[21] is sic1_c in component sic1_c (nanomolar).
* STATES[22] is cdk1clb5_n in component cdk1clb5_n (nanomolar).
* CONSTANTS[34] is k_41 in component rate_constants (first_order_rate_constant).
* STATES[23] is cdk1clb5sic1p_n in component cdk1clb5sic1p_n (nanomolar).
* CONSTANTS[35] is k_31 in component rate_constants (first_order_rate_constant).
* CONSTANTS[36] is k_30 in component rate_constants (second_order_rate_constant).
* CONSTANTS[37] is k_40 in component rate_constants (first_order_rate_constant).
* STATES[24] is cdk1cln3far1_n in component cdk1cln3far1_n (nanomolar).
* STATES[25] is far1_n in component far1_n (nanomolar).
* STATES[26] is cdk1cln3far1p_n in component cdk1cln3far1p_n (nanomolar).
* CONSTANTS[38] is k_36 in component rate_constants (second_order_rate_constant).
* CONSTANTS[39] is k_37 in component rate_constants (second_order_rate_constant).
* STATES[27] is cdk1clb5sic1_n in component cdk1clb5sic1_n (nanomolar).
* CONSTANTS[40] is k_47 in component rate_constants (first_order_rate_constant).
* CONSTANTS[41] is k_38 in component rate_constants (second_order_rate_constant).
* CONSTANTS[42] is k_9 in component rate_constants (flux).
* CONSTANTS[43] is k_18 in component rate_constants (first_order_rate_constant).
* STATES[28] is whi5_c in component whi5_c (nanomolar).
* CONSTANTS[44] is k_8 in component rate_constants (flux).
* CONSTANTS[45] is k_45 in component rate_constants (first_order_rate_constant).
* CONSTANTS[46] is k_17 in component rate_constants (first_order_rate_constant).
* STATES[29] is far1_c in component far1_c (nanomolar).
* CONSTANTS[47] is k_5 in component rate_constants (flux).
* CONSTANTS[48] is k_42 in component rate_constants (first_order_rate_constant).
* CONSTANTS[49] is k_14 in component rate_constants (first_order_rate_constant).
* STATES[30] is whi5p_c in component whi5p_c (nanomolar).
* CONSTANTS[50] is k_52 in component rate_constants (first_order_rate_constant).
* STATES[31] is whi5p_n in component whi5p_n (nanomolar).
* STATES[32] is sic1P_n in component sic1P_n (nanomolar).
* STATES[33] is far1P_n in component far1P_n (nanomolar).
* CONSTANTS[51] is k_22 in component rate_constants (first_order_rate_constant).
* CONSTANTS[52] is k_19 in component rate_constants (first_order_rate_constant).
* CONSTANTS[53] is k_23 in component rate_constants (first_order_rate_constant).
* RATES[0] is d/dt v_c in component v_c (nanomolar).
* RATES[1] is d/dt v_n in component v_n (nanomolar).
* RATES[2] is d/dt mcln2_c in component mcln2_c (nanomolar).
* RATES[4] is d/dt mclb5_c in component mclb5_c (nanomolar).
* RATES[3] is d/dt mcln2_n in component mcln2_n (nanomolar).
* RATES[5] is d/dt mclb5_n in component mclb5_n (nanomolar).
* RATES[6] is d/dt sbf_n in component sbf_n (nanomolar).
* RATES[10] is d/dt cln3_c in component cln3_c (nanomolar).
* RATES[11] is d/dt cln2_c in component cln2_c (nanomolar).
* RATES[14] is d/dt clb5_c in component clb5_c (nanomolar).
* RATES[12] is d/dt cdk1_c in component cdk1_c (nanomolar).
* RATES[17] is d/dt cln3_n in component cln3_n (nanomolar).
* RATES[16] is d/dt cdk1_n in component cdk1_n (nanomolar).
* RATES[13] is d/dt cdk1cln2_c in component cdk1cln2_c (nanomolar).
* RATES[15] is d/dt cdk1clb5_c in component cdk1clb5_c (nanomolar).
* RATES[19] is d/dt cdk1cln2_n in component cdk1cln2_n (nanomolar).
* RATES[22] is d/dt cdk1clb5_n in component cdk1clb5_n (nanomolar).
* RATES[18] is d/dt cdk1cln3_n in component cdk1cln3_n (nanomolar).
* RATES[9] is d/dt sbfwhi5_n in component sbfwhi5_n (nanomolar).
* RATES[7] is d/dt sbfwhi5p_n in component sbfwhi5p_n (nanomolar).
* RATES[24] is d/dt cdk1cln3far1_n in component cdk1cln3far1_n (nanomolar).
* RATES[27] is d/dt cdk1clb5sic1_n in component cdk1clb5sic1_n (nanomolar).
* RATES[23] is d/dt cdk1clb5sic1p_n in component cdk1clb5sic1p_n (nanomolar).
* RATES[26] is d/dt cdk1cln3far1p_n in component cdk1cln3far1p_n (nanomolar).
* RATES[20] is d/dt cdk1clb5sic1_c in component cdk1clb5sic1_c (nanomolar).
* RATES[21] is d/dt sic1_c in component sic1_c (nanomolar).
* RATES[28] is d/dt whi5_c in component whi5_c (nanomolar).
* RATES[29] is d/dt far1_c in component far1_c (nanomolar).
* RATES[30] is d/dt whi5p_c in component whi5p_c (nanomolar).
* RATES[32] is d/dt sic1P_n in component sic1P_n (nanomolar).
* RATES[33] is d/dt far1P_n in component far1P_n (nanomolar).
* RATES[8] is d/dt whi5_n in component whi5_n (nanomolar).
* RATES[25] is d/dt far1_n in component far1_n (nanomolar).
* RATES[31] is d/dt whi5p_n in component whi5p_n (nanomolar).
*/
void
initConsts(double* CONSTANTS, double* RATES, double *STATES)
{
STATES[0] = 0.5;
CONSTANTS[0] = 0.0051;
STATES[1] = 0.5;
STATES[2] = 0;
CONSTANTS[1] = 0.6;
CONSTANTS[2] = 0.12;
STATES[3] = 0;
STATES[4] = 0;
CONSTANTS[3] = 0.6;
CONSTANTS[4] = 0.12;
STATES[5] = 0;
CONSTANTS[5] = 0.03523;
STATES[6] = 0;
CONSTANTS[6] = 0.03523;
CONSTANTS[7] = 1;
CONSTANTS[8] = 8.46;
CONSTANTS[9] = 0.0005;
STATES[7] = 0;
STATES[8] = 0;
STATES[9] = 0.025544;
STATES[10] = 0.000485;
CONSTANTS[10] = 0.00001;
CONSTANTS[11] = 0.005;
CONSTANTS[12] = 0.01;
STATES[11] = 0;
CONSTANTS[13] = 0.32;
CONSTANTS[14] = 2.82;
CONSTANTS[15] = 0.55;
CONSTANTS[16] = 0.1;
STATES[12] = 0.333333;
STATES[13] = 0;
STATES[14] = 0;
CONSTANTS[17] = 0.32;
CONSTANTS[18] = 2.82;
CONSTANTS[19] = 0.55;
CONSTANTS[20] = 0.35;
STATES[15] = 0;
CONSTANTS[21] = 0.01;
CONSTANTS[22] = 0.005;
CONSTANTS[23] = 0.001;
CONSTANTS[24] = 0.03;
STATES[16] = 0.0074127;
STATES[17] = 0;
CONSTANTS[25] = 2.82;
CONSTANTS[26] = 0.55;
CONSTANTS[27] = 0.01;
STATES[18] = 0;
CONSTANTS[28] = 0;
CONSTANTS[29] = 0.1;
CONSTANTS[30] = 0.001;
STATES[19] = 0;
CONSTANTS[31] = 0.55;
CONSTANTS[32] = 84.6;
CONSTANTS[33] = 0.012;
STATES[20] = 0;
STATES[21] = 0.039234;
STATES[22] = 0;
CONSTANTS[34] = 1;
STATES[23] = 0;
CONSTANTS[35] = 0.55;
CONSTANTS[36] = 42300;
CONSTANTS[37] = 1;
STATES[24] = 0;
STATES[25] = 0;
STATES[26] = 0;
CONSTANTS[38] = 4363.6;
CONSTANTS[39] = 4363.6;
STATES[27] = 0;
CONSTANTS[40] = 1;
CONSTANTS[41] = 4363.6;
CONSTANTS[42] = 0.00005;
CONSTANTS[43] = 0.0008;
STATES[28] = 0.073564;
CONSTANTS[44] = 0.00004;
CONSTANTS[45] = 0.005;
CONSTANTS[46] = 0.01;
STATES[29] = 0.0037926;
CONSTANTS[47] = 0.000042;
CONSTANTS[48] = 0.005;
CONSTANTS[49] = 0.01;
STATES[30] = 0;
CONSTANTS[50] = 0.005;
STATES[31] = 0;
STATES[32] = 0;
STATES[33] = 0;
CONSTANTS[51] = 0.01;
CONSTANTS[52] = 0.01;
CONSTANTS[53] = 0.01;
CONSTANTS[54] = 0.00000;
}
void
computeRates(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
RATES[1] = CONSTANTS[54];
RATES[3] = CONSTANTS[5]*STATES[6] - CONSTANTS[1]*STATES[3];
RATES[5] = CONSTANTS[6]*STATES[6] - CONSTANTS[3]*STATES[5];
RATES[6] = ( CONSTANTS[7]*STATES[7] - CONSTANTS[8]*STATES[6]*STATES[8])+ CONSTANTS[9]*STATES[9];
RATES[18] = ((( CONSTANTS[25]*STATES[17]*STATES[16] - CONSTANTS[26]*STATES[18])+ CONSTANTS[35]*STATES[24]) - CONSTANTS[36]*STATES[25]*STATES[18])+ CONSTANTS[37]*STATES[26];
RATES[9] = ( CONSTANTS[8]*STATES[6]*STATES[8] - CONSTANTS[9]*STATES[9]) - CONSTANTS[38]*STATES[9]*STATES[18];
RATES[7] = CONSTANTS[38]*STATES[9]*STATES[18] - CONSTANTS[7]*STATES[7];
RATES[24] = ( CONSTANTS[36]*STATES[25]*STATES[18] - CONSTANTS[35]*STATES[24]) - CONSTANTS[39]*STATES[24]*STATES[19];
RATES[23] = CONSTANTS[41]*STATES[27]*STATES[19] - CONSTANTS[34]*STATES[23];
RATES[26] = CONSTANTS[39]*STATES[24]*STATES[19] - CONSTANTS[37]*STATES[26];
RATES[32] = CONSTANTS[34]*STATES[23];
RATES[33] = CONSTANTS[37]*STATES[26];
RATES[31] = ( CONSTANTS[7]*STATES[7] - CONSTANTS[50]*STATES[31]) - CONSTANTS[53]*STATES[31];
ALGEBRAIC[0] = CONSTANTS[0]*STATES[0];
RATES[0] = ALGEBRAIC[0];
RATES[10] = ((CONSTANTS[10] - CONSTANTS[11]*STATES[10]) - CONSTANTS[12]*STATES[10]) - (ALGEBRAIC[0]/STATES[0])*STATES[10];
RATES[11] = ((( CONSTANTS[13]*STATES[2] - CONSTANTS[14]*STATES[12]*STATES[11])+ CONSTANTS[15]*STATES[13]) - CONSTANTS[16]*STATES[11]) - (ALGEBRAIC[0]/STATES[0])*STATES[11];
RATES[14] = ((( CONSTANTS[17]*STATES[4] - CONSTANTS[18]*STATES[14]*STATES[12])+ CONSTANTS[19]*STATES[15]) - CONSTANTS[20]*STATES[14]) - (ALGEBRAIC[0]/STATES[0])*STATES[14];
RATES[12] = ((((((CONSTANTS[21] - CONSTANTS[22]*STATES[12])+ CONSTANTS[23]*STATES[16]+ CONSTANTS[15]*STATES[13]) - CONSTANTS[14]*STATES[12]*STATES[11]) - CONSTANTS[18]*STATES[12]*STATES[14])+ CONSTANTS[19]*STATES[15]) - CONSTANTS[24]*STATES[12]) - (ALGEBRAIC[0]/STATES[0])*STATES[12];
RATES[15] = (((( CONSTANTS[18]*STATES[12]*STATES[14] - CONSTANTS[19]*STATES[15])+ CONSTANTS[31]*STATES[20]) - CONSTANTS[32]*STATES[21]*STATES[15]) - CONSTANTS[33]*STATES[15]) - (ALGEBRAIC[0]/STATES[0])*STATES[15];
RATES[20] = (( CONSTANTS[32]*STATES[21]*STATES[15] - CONSTANTS[31]*STATES[20]) - CONSTANTS[40]*STATES[20]) - (ALGEBRAIC[0]/STATES[0])*STATES[20];
RATES[21] = (((CONSTANTS[42] - CONSTANTS[32]*STATES[21]*STATES[15])+ CONSTANTS[31]*STATES[20]) - CONSTANTS[43]*STATES[21]) - (ALGEBRAIC[0]/STATES[0])*STATES[21];
RATES[28] = ((CONSTANTS[44] - CONSTANTS[45]*STATES[28]) - CONSTANTS[46]*STATES[28]) - (ALGEBRAIC[0]/STATES[0])*STATES[28];
RATES[29] = ((CONSTANTS[47] - CONSTANTS[48]*STATES[29]) - CONSTANTS[49]*STATES[29]) - (ALGEBRAIC[0]/STATES[0])*STATES[29];
ALGEBRAIC[1] = STATES[1]/STATES[0];
RATES[2] = ( CONSTANTS[1]*STATES[3]*ALGEBRAIC[1] - CONSTANTS[2]*STATES[2]) - (ALGEBRAIC[0]/STATES[0])*STATES[2];
RATES[4] = ( CONSTANTS[3]*STATES[5]*ALGEBRAIC[1] - CONSTANTS[4]*STATES[4]) - (ALGEBRAIC[0]/STATES[0])*STATES[4];
RATES[17] = ((( CONSTANTS[11]*STATES[10])/ALGEBRAIC[1] - CONSTANTS[25]*STATES[17]*STATES[16])+ CONSTANTS[26]*STATES[18]) - CONSTANTS[27]*STATES[17];
RATES[16] = (((( CONSTANTS[22]*STATES[12])/ALGEBRAIC[1] - CONSTANTS[23]*STATES[16]) - CONSTANTS[25]*STATES[17]*STATES[16])+ CONSTANTS[26]*STATES[18]) - CONSTANTS[28]*STATES[16];
RATES[13] = ((( CONSTANTS[14]*STATES[12]*STATES[11] - CONSTANTS[15]*STATES[13]) - CONSTANTS[29]*STATES[13])+ CONSTANTS[30]*STATES[19]*ALGEBRAIC[1]) - (ALGEBRAIC[0]/STATES[0])*STATES[13];
RATES[19] = ( CONSTANTS[29]*STATES[13])/ALGEBRAIC[1] - CONSTANTS[30]*STATES[19];
RATES[22] = CONSTANTS[34]*STATES[23]+( CONSTANTS[33]*STATES[15])/ALGEBRAIC[1];
RATES[27] = ( CONSTANTS[40]*STATES[20])/ALGEBRAIC[1] - CONSTANTS[41]*STATES[27]*STATES[19];
RATES[30] = CONSTANTS[50]*STATES[31]*ALGEBRAIC[1];
RATES[8] = (( CONSTANTS[45]*STATES[28])/ALGEBRAIC[1] - CONSTANTS[8]*STATES[8]*STATES[6]) - CONSTANTS[51]*STATES[8];
RATES[25] = ((( CONSTANTS[48]*STATES[29])/ALGEBRAIC[1] - CONSTANTS[36]*STATES[25]*STATES[18])+ CONSTANTS[35]*STATES[24]) - CONSTANTS[52]*STATES[25];
}
void
computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[0] = CONSTANTS[0]*STATES[0];
ALGEBRAIC[1] = STATES[1]/STATES[0];
}