Generated Code
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The raw code is available.
C
C There are a total of 2 entries in the algebraic variable array.
C There are a total of 13 entries in each of the rate and state variable arrays.
C There are a total of 30 entries in the constant variable array.
C
C
C VOI is time in component environment (minute).
C STATES(1) is cAMP in component cAMP (micromolar).
C CONSTS(1) is Ko in component cAMP (dimensionless).
C CONSTS(2) is Ka in component cAMP (per_micromolar).
C CONSTS(3) is Kb in component cAMP (per_micromolar).
C CONSTS(4) is Kdsm in component cAMP (micromolar).
C CONSTS(5) is Vmsm in component cAMP (flux).
C CONSTS(6) is Vdsm in component cAMP (flux).
C ALGBRC(1) is ACTH in component cAMP (micromolar).
C ALGBRC(2) is IS in component IS (dimensionless).
C CONSTS(7) is Crpt in component IS (dimensionless).
C CONSTS(8) is K in component IS (dimensionless).
C CONSTS(9) is Kd in component IS (micromolar).
C CONSTS(10) is n in component IS (dimensionless).
C STATES(2) is V in component V (flux).
C CONSTS(11) is P in component V (micromolar_per_minute2).
C CONSTS(12) is Q in component V (first_order_rate_constant).
C STATES(3) is W in component W (flux).
C CONSTS(13) is T in component W (micromolar2_per_minute2).
C CONSTS(14) is U in component W (first_order_rate_constant).
C STATES(4) is CHOC in component CHOC (micromolar).
C CONSTS(15) is Lmtr in component model_parameters (first_order_rate_constant).
C STATES(5) is Kmtr in component Kmtr (first_order_rate_constant).
C STATES(6) is CHOM in component CHOM (micromolar).
C CONSTS(16) is Kbac in component model_parameters (first_order_rate_constant).
C STATES(7) is Kfor in component Kfor (first_order_rate_constant).
C CONSTS(17) is Kcb in component model_parameters (first_order_rate_constant).
C CONSTS(18) is Kcf in component model_parameters (first_order_rate_constant).
C STATES(8) is CHON in component CHON (micromolar).
C STATES(9) is CHOL in component CHOL (micromolar).
C CONSTS(19) is C in component Kmtr (per_minute2).
C CONSTS(20) is D in component Kmtr (first_order_rate_constant).
C CONSTS(21) is R in component Kfor (per_minute2).
C CONSTS(22) is S in component Kfor (first_order_rate_constant).
C CONSTS(23) is Vm in component model_parameters (flux).
C CONSTS(24) is Km in component model_parameters (micromolar).
C STATES(10) is PREG in component PREG (micromolar).
C CONSTS(25) is Vmptr in component model_parameters (flux).
C CONSTS(26) is Kmptr in component model_parameters (micromolar).
C STATES(11) is PRO in component PRO (micromolar).
C CONSTS(27) is HA in component PRO (dimensionless).
C CONSTS(28) is AH in component model_parameters (first_order_rate_constant).
C STATES(12) is HYPR in component HYPR (micromolar).
C CONSTS(29) is HY in component model_parameters (first_order_rate_constant).
C STATES(13) is CORT in component CORT (micromolar).
C CONSTS(30) is LH in component CORT (first_order_rate_constant).
C RATES(1) is d/dt cAMP in component cAMP (micromolar).
C RATES(2) is d/dt V in component V (flux).
C RATES(3) is d/dt W in component W (flux).
C RATES(4) is d/dt CHOC in component CHOC (micromolar).
C RATES(6) is d/dt CHOM in component CHOM (micromolar).
C RATES(9) is d/dt CHOL in component CHOL (micromolar).
C RATES(5) is d/dt Kmtr in component Kmtr (first_order_rate_constant).
C RATES(7) is d/dt Kfor in component Kfor (first_order_rate_constant).
C RATES(8) is d/dt CHON in component CHON (micromolar).
C RATES(10) is d/dt PREG in component PREG (micromolar).
C RATES(11) is d/dt PRO in component PRO (micromolar).
C RATES(12) is d/dt HYPR in component HYPR (micromolar).
C RATES(13) is d/dt CORT in component CORT (micromolar).
C
SUBROUTINE initConsts(CONSTS, RATES, STATES)
REAL CONSTS(*), RATES(*), STATES(*)
STATES(1) = 0.95
CONSTS(1) = 0.013
CONSTS(2) = 10
CONSTS(3) = 1000000.0
CONSTS(4) = 10.0
CONSTS(5) = 6.0
CONSTS(6) = 10.0
CONSTS(7) = 3.0
CONSTS(8) = 80.0
CONSTS(9) = 2.11
CONSTS(10) = 4.0
STATES(2) = 11.3
CONSTS(11) = 0.052
CONSTS(12) = 0.042
STATES(3) = 10.0
CONSTS(13) = 8.0
CONSTS(14) = 0.0015
STATES(4) = 532.0
CONSTS(15) = 1.65
STATES(5) = 0.446
STATES(6) = 139.0
CONSTS(16) = 10.0
STATES(7) = 0.370
CONSTS(17) = 0.01
CONSTS(18) = 0.00033
STATES(8) = 3.03
STATES(9) = 3000.0
CONSTS(19) = 6.25
CONSTS(20) = 125.0
CONSTS(21) = 3.0
CONSTS(22) = 76.0
CONSTS(23) = 1890.0
CONSTS(24) = 270.0
STATES(10) = 6.56
CONSTS(25) = 500.0
CONSTS(26) = 150.0
STATES(11) = 0.64
CONSTS(27) = 0.5
CONSTS(28) = 16.4
STATES(12) = 0.64
CONSTS(29) = 16.4
STATES(13) = 5.2
CONSTS(30) = 0.724
RETURN
END
SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC)
REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*)
RATES(3) = CONSTS(13)*STATES(4) ** -1.00000 - CONSTS(14)*STATES(3)
RATES(4) = (STATES(2)+STATES(3)+ CONSTS(15)*STATES(6)) - STATES(5)*STATES(4)
RATES(6) = ( STATES(5)*STATES(4)+ CONSTS(16)*STATES(8)+ CONSTS(18)*STATES(9)) - ( CONSTS(15)*STATES(6)+ CONSTS(17)*STATES(6)+ STATES(7)*STATES(6))
RATES(9) = CONSTS(17)*STATES(6) - CONSTS(18)*STATES(9)
RATES(8) = STATES(7)*STATES(6) - ( CONSTS(16)*STATES(8)+( CONSTS(23)*STATES(8))/(CONSTS(24)+STATES(8)))
RATES(10) = ( CONSTS(23)*STATES(8))/(CONSTS(24)+STATES(8)) - ( CONSTS(25)*STATES(10))/(CONSTS(26)+STATES(10))
RATES(11) = CONSTS(27)*(( CONSTS(25)*STATES(10))/(CONSTS(26)+STATES(10))) - CONSTS(28)*STATES(11)
RATES(12) = CONSTS(28)*STATES(11) - CONSTS(29)*STATES(12)
RATES(13) = CONSTS(29)*STATES(12) - CONSTS(30)*STATES(13)
ALGBRC(1) = TERNRY(VOI.GE.0.00000.AND.VOI.LT.10.0000, 1.20000e-05, TERNRY(VOI.GE.10.0000.AND.VOI.LT.20.0000, 1.60000e-05, TERNRY(VOI.GE.20.0000.AND.VOI.LT.35.0000, 1.20000e-05, TERNRY(VOI.GE.35.0000.AND.VOI.LT.45.0000, 1.60000e-05, 1.20000e-05)
RATES(1) = ( CONSTS(5)*CONSTS(1)*(1.00000+ CONSTS(3)*ALGBRC(1)))/((1.00000+ CONSTS(2)*ALGBRC(1))+ CONSTS(1)*(1.00000+ CONSTS(3)*ALGBRC(1))) - ( CONSTS(6)*STATES(1))/(CONSTS(4)+STATES(1))
ALGBRC(2) = ( CONSTS(8)*CONSTS(7)*STATES(1) ** CONSTS(10))/(CONSTS(9) ** CONSTS(10)+STATES(1) ** CONSTS(10))
RATES(2) = CONSTS(11)*ALGBRC(2) - CONSTS(12)*STATES(2)
RATES(5) = CONSTS(19)*ALGBRC(2) - CONSTS(20)*STATES(5)
RATES(7) = CONSTS(21)*ALGBRC(2) - CONSTS(22)*STATES(7)
RETURN
END
SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC)
REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*)
ALGBRC(1) = TERNRY(VOI.GE.0.00000.AND.VOI.LT.10.0000, 1.20000e-05, TERNRY(VOI.GE.10.0000.AND.VOI.LT.20.0000, 1.60000e-05, TERNRY(VOI.GE.20.0000.AND.VOI.LT.35.0000, 1.20000e-05, TERNRY(VOI.GE.35.0000.AND.VOI.LT.45.0000, 1.60000e-05, 1.20000e-05)
ALGBRC(2) = ( CONSTS(8)*CONSTS(7)*STATES(1) ** CONSTS(10))/(CONSTS(9) ** CONSTS(10)+STATES(1) ** CONSTS(10))
RETURN
END
REAL FUNCTION TERNRY(TEST, VALA, VALB)
LOGICAL TEST
REAL VALA, VALB
IF (TEST) THEN
TERNRY = VALA
ELSE
TERNRY = VALB
ENDIF
RETURN
END
