The University of Auckland
Auckland Bioengineering Institute
2007-06-01 00:00
Steven Niederer
Nicholas
Smith
P
Biophysical Journal
This CellML model has been created by the author of the paper on which it is based. It has been curated to a high standard and is known to reproduce the published results in PCEnv and COR.
Steven
Niederer
cardiac
electrophysiology
A Mathematical Model of the Slow Force Response to Stretch in Rat Ventricular Myocytes
92
4030
4044
This cell model provides a descripition of the Electrophysiology, Calcium, pH and Mechanics of the rat ventricular myocte at room temperature.
The model includes representations of length dependent channels NHE & AE and RyR, that can be turned on or off as desired. The model was used to demonstrate the importance of stretch activated channels in regulating the slow force response.
It has also been used in tissue models and can be readily coupled to tissue deformation models (Niederer and Smith Progress in Biophysics and Molecular Biology 2007).
The model uses Hinch 2004 (Biophysical Journal) Ca++ dynamics, Pandit 2001 rat electrophysiology and Niederer 2006 mechanics.
The University of Auckland
17369410
s.niederer@gmail.com
Steven
Niederer
A
James Lawson
keyword
10000
10000
2008-02-02T00:00:00+13:00