Generated Code
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The raw code is available.
# Size of variable arrays:
sizeAlgebraic = 2
sizeStates = 5
sizeConstants = 20
from math import *
from numpy import *
def createLegends():
legend_states = [""] * sizeStates
legend_rates = [""] * sizeStates
legend_algebraic = [""] * sizeAlgebraic
legend_voi = ""
legend_constants = [""] * sizeConstants
legend_voi = "t in component environment (second)"
legend_constants[0] = "D_Ca in component parameters (second)"
legend_constants[1] = "k_1 in component parameters (per_second)"
legend_constants[2] = "k_2 in component parameters (per_second)"
legend_constants[3] = "f in component parameters (per_second)"
legend_constants[4] = "g in component parameters (per_second)"
legend_constants[5] = "Ca_max in component parameters (dimensionless)"
legend_constants[6] = "Total_Tn in component parameters (dimensionless)"
legend_constants[7] = "Total_CB in component parameters (dimensionless)"
legend_algebraic[0] = "Ca_t in component Ca_t (dimensionless)"
legend_states[0] = "TnCa in component TnCa (dimensionless)"
legend_states[1] = "CB_on in component CB_on (dimensionless)"
legend_states[2] = "CumCB_on in component CumCB (dimensionless)"
legend_states[3] = "CumCB_off in component CumCB (dimensionless)"
legend_algebraic[1] = "F in component force_development (force)"
legend_states[4] = "FTI in component force_development (force_second)"
legend_constants[15] = "FLA in component force_development (energy)"
legend_constants[8] = "phi in component force_development (force)"
legend_constants[9] = "s in component force_development (dimensionless)"
legend_constants[10] = "L in component force_development (meter)"
legend_constants[11] = "L_0 in component force_development (meter)"
legend_constants[12] = "F_max in component force_development (force)"
legend_constants[17] = "ATP in component ATP (dimensionless)"
legend_constants[18] = "ATP_energy in component ATP (energy)"
legend_constants[13] = "epsilon in component ATP (energy)"
legend_constants[14] = "CumCB_on_end in component ATP (dimensionless)"
legend_constants[19] = "Efficiency in component equations_main (dimensionless)"
legend_constants[16] = "Economy in component equations_main (second_per_meter)"
legend_rates[0] = "d/dt TnCa in component TnCa (dimensionless)"
legend_rates[1] = "d/dt CB_on in component CB_on (dimensionless)"
legend_rates[2] = "d/dt CumCB_on in component CumCB (dimensionless)"
legend_rates[3] = "d/dt CumCB_off in component CumCB (dimensionless)"
legend_rates[4] = "d/dt FTI in component force_development (force_second)"
return (legend_states, legend_algebraic, legend_voi, legend_constants)
def initConsts():
constants = [0.0] * sizeConstants; states = [0.0] * sizeStates;
constants[0] = 0.1
constants[1] = 40
constants[2] = 20
constants[3] = 10
constants[4] = 10
constants[5] = 1
constants[6] = 1
constants[7] = 1
states[0] = 0
states[1] = 0
states[2] = 0
states[3] = 0
states[4] = 0
constants[8] = 1
constants[9] = 1
constants[10] = 1
constants[11] = 0
constants[12] = 0.228
constants[13] = 1
constants[14] = 1
constants[15] = constants[12]*constants[9]*(constants[10]-constants[11])
constants[16] = (constants[8]/constants[13])*(1.00000/constants[4])
constants[17] = constants[14]
constants[18] = constants[17]*constants[13]
constants[19] = constants[15]/constants[18]
return (states, constants)
def computeRates(voi, states, constants):
rates = [0.0] * sizeStates; algebraic = [0.0] * sizeAlgebraic
rates[1] = constants[3]*states[0]*(constants[7]-states[1])-constants[4]*states[1]
rates[2] = constants[3]*states[0]*(constants[7]-states[1])
rates[3] = constants[4]*states[1]
algebraic[0] = custom_piecewise([greater_equal(voi , 0.00000) & less(voi , 0.300000*constants[0]), (constants[5]*(1.00000+sin(( pi*(voi/constants[0]-0.150000))/0.300000)))/2.00000 , greater_equal(voi , 0.300000*constants[0]) & less(voi , constants[0]), (constants[5]*(1.00000-sin(( pi*(voi/constants[0]-0.650000))/0.700000)))/2.00000 , True, 0.00000])
rates[0] = constants[1]*algebraic[0]*(constants[6]-states[0])-constants[2]*states[0]
algebraic[1] = states[1]*constants[8]
rates[4] = algebraic[1]
return(rates)
def computeAlgebraic(constants, states, voi):
algebraic = array([[0.0] * len(voi)] * sizeAlgebraic)
states = array(states)
voi = array(voi)
algebraic[0] = custom_piecewise([greater_equal(voi , 0.00000) & less(voi , 0.300000*constants[0]), (constants[5]*(1.00000+sin(( pi*(voi/constants[0]-0.150000))/0.300000)))/2.00000 , greater_equal(voi , 0.300000*constants[0]) & less(voi , constants[0]), (constants[5]*(1.00000-sin(( pi*(voi/constants[0]-0.650000))/0.700000)))/2.00000 , True, 0.00000])
algebraic[1] = states[1]*constants[8]
return algebraic
def custom_piecewise(cases):
"""Compute result of a piecewise function"""
return select(cases[0::2],cases[1::2])
def solve_model():
"""Solve model with ODE solver"""
from scipy.integrate import ode
# Initialise constants and state variables
(init_states, constants) = initConsts()
# Set timespan to solve over
voi = linspace(0, 10, 500)
# Construct ODE object to solve
r = ode(computeRates)
r.set_integrator('vode', method='bdf', atol=1e-06, rtol=1e-06, max_step=1)
r.set_initial_value(init_states, voi[0])
r.set_f_params(constants)
# Solve model
states = array([[0.0] * len(voi)] * sizeStates)
states[:,0] = init_states
for (i,t) in enumerate(voi[1:]):
if r.successful():
r.integrate(t)
states[:,i+1] = r.y
else:
break
# Compute algebraic variables
algebraic = computeAlgebraic(constants, states, voi)
return (voi, states, algebraic)
def plot_model(voi, states, algebraic):
"""Plot variables against variable of integration"""
import pylab
(legend_states, legend_algebraic, legend_voi, legend_constants) = createLegends()
pylab.figure(1)
pylab.plot(voi,vstack((states,algebraic)).T)
pylab.xlabel(legend_voi)
pylab.legend(legend_states + legend_algebraic, loc='best')
pylab.show()
if __name__ == "__main__":
(voi, states, algebraic) = solve_model()
plot_model(voi, states, algebraic)
