drosophila
circadian rhythm
signal transduction
circadian rhythms
oscillator
keyword
Added simulation metadata and cmeta:id's to some variables
Per_c
cytosolic Per protein
nuclear Clk-Cyc protein complex
CC_n
11403560
406
Robust oscillations within the interlocked feedback model of Drosophila circadian rhythm
210
401
This CellML model is known to run in both PCEnv and COR to replicate the published results. The units have been checked and they are consistent.
Ueda et al.'s mathematical model of circadian rhythms in Drosophila.
Drosophila
Added initial conditions to all the substrates (these were based on the values used in the corresponding SBML model in the BioModels database), and fixed a typo in the equation for dPTc/dt such that the first term in this equation now reads V1*Perc*Timc rather than V1*Perc*PTc.
CC_c
cytosolic Clk-Cyc protein complex
cytosolic Clk protein
Clk_c
Lawson
James
Richard
The University of Auckland, Auckland Bioengineering Institute
Catherine
Lloyd
May
R
Hiroki
Ueda
2008-10-20T14:24:23+13:00
Catherine Lloyd
c.lloyd@auckland.ac.nz
Catherine
May
Lloyd
This is the CellML description of Ueda et al.'s mathematical model of circadian rhythms in Drosophila.
Catherine Lloyd
10000
1000
0.1
cytosolic Per-Tim protein complex
PT_c
2003-09-23T00:00:00+00:00
Tim mRNA
Tim_m
Auckland Bioengineering Institute
The University of Auckland
Per mRNA
Per_m
2001-06-21
Clk mRNA
Clk_m
Kitano
Hiroaki
Journal of Theoretical Biology
Hagiwara
Masatoshi
Cyc_c
cytosolic Cyc protein
Tim_c
cytosolic Tim protein
nuclear Per-Tim protein complex
PT_n
2008-10-14T15:10:39+13:00