/* There are a total of 3 entries in the algebraic variable array. There are a total of 3 entries in each of the rate and state variable arrays. There are a total of 13 entries in the constant variable array. */ /* * VOI is time in component enviroment (second). * STATES[0] is P in component P (micromolar). * CONSTANTS[0] is V_p in component P (per_second). * CONSTANTS[1] is k_p in component P (micromolar). * CONSTANTS[2] is IPR_3_flux in component P (flux). * STATES[1] is c in component c (micromolar). * ALGEBRAIC[2] is J_flux in component J_flux (flux). * ALGEBRAIC[0] is J_pump in component J_pump (flux). * CONSTANTS[12] is J_leak in component J_leak (flux). * CONSTANTS[3] is k_flux in component J_flux (micromolar_per_second). * ALGEBRAIC[1] is mu in component mu (dimensionless). * STATES[2] is h in component h (dimensionless). * CONSTANTS[4] is b in component J_flux (dimensionless). * CONSTANTS[5] is k_1 in component J_flux (micromolar). * CONSTANTS[6] is gamma in component J_pump (micromolar_per_second). * CONSTANTS[7] is k_gamma in component J_pump (micromolar). * CONSTANTS[8] is beta in component J_leak (flux). * CONSTANTS[9] is k_mu in component mu (micromolar). * CONSTANTS[10] is k_2 in component h (micromolar). * CONSTANTS[11] is tau_h in component h (second). * RATES[0] is d/dt P in component P (micromolar). * RATES[1] is d/dt c in component c (micromolar). * RATES[2] is d/dt h in component h (dimensionless). */ void initConsts(double* CONSTANTS, double* RATES, double *STATES) { STATES[0] = 0; CONSTANTS[0] = 0.08; CONSTANTS[1] = 1; CONSTANTS[2] = 0.72; STATES[1] = 0.3; CONSTANTS[3] = 3; STATES[2] = 1; CONSTANTS[4] = 0.11; CONSTANTS[5] = 0.7; CONSTANTS[6] = 1; CONSTANTS[7] = 0.27; CONSTANTS[8] = 0.15; CONSTANTS[9] = 0.01; CONSTANTS[10] = 0.7; CONSTANTS[11] = 0.2; CONSTANTS[12] = CONSTANTS[8]; } void computeRates(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC) { RATES[0] = (VOI<=15.0000 ? CONSTANTS[2] - ( CONSTANTS[0]*STATES[0]*CONSTANTS[1])/(CONSTANTS[1]+STATES[0]) : ( - CONSTANTS[0]*STATES[0]*CONSTANTS[1])/(CONSTANTS[1]+STATES[0])); RATES[2] = (pow(CONSTANTS[10], 2.00000)/(pow(CONSTANTS[10], 2.00000)+pow(STATES[1], 2.00000)) - STATES[2])/CONSTANTS[11]; ALGEBRAIC[1] = pow(STATES[0], 3.00000)/(pow(CONSTANTS[9], 3.00000)+pow(STATES[0], 3.00000)); ALGEBRAIC[2] = CONSTANTS[3]*ALGEBRAIC[1]*STATES[2]*(CONSTANTS[4]+( (1.00000 - CONSTANTS[4])*STATES[1])/(CONSTANTS[5]+STATES[1])); ALGEBRAIC[0] = ( CONSTANTS[6]*pow(STATES[1], 2.00000))/(pow(CONSTANTS[7], 2.00000)+pow(STATES[1], 2.00000)); RATES[1] = (ALGEBRAIC[2] - ALGEBRAIC[0])+CONSTANTS[12]; } void computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC) { ALGEBRAIC[1] = pow(STATES[0], 3.00000)/(pow(CONSTANTS[9], 3.00000)+pow(STATES[0], 3.00000)); ALGEBRAIC[2] = CONSTANTS[3]*ALGEBRAIC[1]*STATES[2]*(CONSTANTS[4]+( (1.00000 - CONSTANTS[4])*STATES[1])/(CONSTANTS[5]+STATES[1])); ALGEBRAIC[0] = ( CONSTANTS[6]*pow(STATES[1], 2.00000))/(pow(CONSTANTS[7], 2.00000)+pow(STATES[1], 2.00000)); }