Generated Code
The following is c code generated by the CellML API from this CellML file. (Back to language selection)
The raw code is available.
/*
There are a total of 49 entries in the algebraic variable array.
There are a total of 29 entries in each of the rate and state variable arrays.
There are a total of 51 entries in the constant variable array.
*/
/*
* VOI is time in component environment (second).
* STATES[0] is V in component membrane (millivolt).
* CONSTANTS[0] is R in component membrane (millijoule_per_mole_kelvin).
* CONSTANTS[1] is T in component membrane (kelvin).
* CONSTANTS[2] is F in component membrane (coulomb_per_mole).
* CONSTANTS[3] is Cm in component membrane (nanoF).
* ALGEBRAIC[26] is i_Na in component sodium_current (picoA).
* ALGEBRAIC[28] is i_Ca_L in component L_type_Ca_channel (picoA).
* ALGEBRAIC[30] is i_t in component Ca_independent_transient_outward_K_current (picoA).
* ALGEBRAIC[31] is i_sus in component sustained_outward_K_current (picoA).
* ALGEBRAIC[35] is i_K1 in component inward_rectifier (picoA).
* ALGEBRAIC[34] is i_Kr in component delayed_rectifier_K_currents (picoA).
* ALGEBRAIC[32] is i_Ks in component delayed_rectifier_K_currents (picoA).
* ALGEBRAIC[36] is i_B_Na in component background_currents (picoA).
* ALGEBRAIC[38] is i_B_Ca in component background_currents (picoA).
* ALGEBRAIC[39] is i_NaK in component sodium_potassium_pump (picoA).
* ALGEBRAIC[40] is i_CaP in component sarcolemmal_calcium_pump_current (picoA).
* ALGEBRAIC[41] is i_NaCa in component Na_Ca_ion_exchanger_current (picoA).
* ALGEBRAIC[0] is i_Stim in component membrane (picoA).
* CONSTANTS[4] is stim_start in component membrane (second).
* CONSTANTS[5] is stim_end in component membrane (second).
* CONSTANTS[6] is stim_period in component membrane (second).
* CONSTANTS[7] is stim_duration in component membrane (second).
* CONSTANTS[8] is stim_amplitude in component membrane (picoA).
* ALGEBRAIC[12] is E_Na in component sodium_current (millivolt).
* CONSTANTS[9] is P_Na in component sodium_current (nanolitre_per_second).
* STATES[1] is Na_c in component cleft_space_ion_concentrations (millimolar).
* STATES[2] is Na_i in component intracellular_ion_concentrations (millimolar).
* STATES[3] is m in component sodium_current_m_gate (dimensionless).
* STATES[4] is h1 in component sodium_current_h1_gate (dimensionless).
* STATES[5] is h2 in component sodium_current_h2_gate (dimensionless).
* ALGEBRAIC[1] is m_infinity in component sodium_current_m_gate (dimensionless).
* ALGEBRAIC[13] is tau_m in component sodium_current_m_gate (second).
* ALGEBRAIC[2] is h_infinity in component sodium_current_h1_gate (dimensionless).
* ALGEBRAIC[14] is tau_h1 in component sodium_current_h1_gate (second).
* ALGEBRAIC[15] is tau_h2 in component sodium_current_h2_gate (second).
* CONSTANTS[10] is g_Ca_L in component L_type_Ca_channel (nanoS).
* CONSTANTS[11] is E_Ca_app in component L_type_Ca_channel (millivolt).
* ALGEBRAIC[27] is f_Ca in component L_type_Ca_channel (dimensionless).
* CONSTANTS[12] is k_Ca in component L_type_Ca_channel (millimolar).
* STATES[6] is Ca_d in component intracellular_ion_concentrations (millimolar).
* STATES[7] is d_L in component L_type_Ca_channel_d_L_gate (dimensionless).
* STATES[8] is f_L_1 in component L_type_Ca_channel_f_L1_gate (dimensionless).
* STATES[9] is f_L_2 in component L_type_Ca_channel_f_L2_gate (dimensionless).
* ALGEBRAIC[3] is d_L_infinity in component L_type_Ca_channel_d_L_gate (dimensionless).
* ALGEBRAIC[16] is tau_d_L in component L_type_Ca_channel_d_L_gate (second).
* ALGEBRAIC[4] is f_L_infinity in component L_type_Ca_channel_f_L1_gate (dimensionless).
* ALGEBRAIC[17] is tau_f_L1 in component L_type_Ca_channel_f_L1_gate (second).
* ALGEBRAIC[18] is tau_f_L2 in component L_type_Ca_channel_f_L2_gate (second).
* ALGEBRAIC[29] is E_K in component Ca_independent_transient_outward_K_current (millivolt).
* CONSTANTS[13] is g_t in component Ca_independent_transient_outward_K_current (nanoS).
* STATES[10] is K_c in component cleft_space_ion_concentrations (millimolar).
* STATES[11] is K_i in component intracellular_ion_concentrations (millimolar).
* STATES[12] is r in component Ca_independent_transient_outward_K_current_r_gate (dimensionless).
* STATES[13] is s in component Ca_independent_transient_outward_K_current_s_gate (dimensionless).
* ALGEBRAIC[19] is tau_r in component Ca_independent_transient_outward_K_current_r_gate (second).
* ALGEBRAIC[5] is r_infinity in component Ca_independent_transient_outward_K_current_r_gate (dimensionless).
* ALGEBRAIC[20] is tau_s in component Ca_independent_transient_outward_K_current_s_gate (second).
* ALGEBRAIC[6] is s_infinity in component Ca_independent_transient_outward_K_current_s_gate (dimensionless).
* CONSTANTS[14] is g_sus in component sustained_outward_K_current (nanoS).
* STATES[14] is r_sus in component sustained_outward_K_current_r_sus_gate (dimensionless).
* STATES[15] is s_sus in component sustained_outward_K_current_s_sus_gate (dimensionless).
* ALGEBRAIC[21] is tau_r_sus in component sustained_outward_K_current_r_sus_gate (second).
* ALGEBRAIC[7] is r_sus_infinity in component sustained_outward_K_current_r_sus_gate (dimensionless).
* ALGEBRAIC[22] is tau_s_sus in component sustained_outward_K_current_s_sus_gate (second).
* ALGEBRAIC[8] is s_sus_infinity in component sustained_outward_K_current_s_sus_gate (dimensionless).
* CONSTANTS[15] is g_Ks in component delayed_rectifier_K_currents (nanoS).
* CONSTANTS[16] is g_Kr in component delayed_rectifier_K_currents (nanoS).
* STATES[16] is n in component delayed_rectifier_K_currents_n_gate (dimensionless).
* STATES[17] is p_a in component delayed_rectifier_K_currents_pa_gate (dimensionless).
* ALGEBRAIC[33] is p_i in component delayed_rectifier_K_currents_pi_gate (dimensionless).
* ALGEBRAIC[23] is tau_n in component delayed_rectifier_K_currents_n_gate (second).
* ALGEBRAIC[9] is n_infinity in component delayed_rectifier_K_currents_n_gate (dimensionless).
* ALGEBRAIC[24] is tau_p_a in component delayed_rectifier_K_currents_pa_gate (second).
* ALGEBRAIC[10] is p_a_infinity in component delayed_rectifier_K_currents_pa_gate (dimensionless).
* CONSTANTS[17] is g_K1 in component inward_rectifier (nanoS).
* CONSTANTS[18] is g_B_Na in component background_currents (nanoS).
* CONSTANTS[19] is g_B_Ca in component background_currents (nanoS).
* ALGEBRAIC[37] is E_Ca in component background_currents (millivolt).
* STATES[18] is Ca_c in component cleft_space_ion_concentrations (millimolar).
* STATES[19] is Ca_i in component intracellular_ion_concentrations (millimolar).
* CONSTANTS[20] is k_NaK_K in component sodium_potassium_pump (millimolar).
* CONSTANTS[21] is k_NaK_Na in component sodium_potassium_pump (millimolar).
* CONSTANTS[22] is i_NaK_max in component sodium_potassium_pump (picoA).
* CONSTANTS[23] is i_CaP_max in component sarcolemmal_calcium_pump_current (picoA).
* CONSTANTS[24] is k_CaP in component sarcolemmal_calcium_pump_current (millimolar).
* CONSTANTS[25] is k_NaCa in component Na_Ca_ion_exchanger_current (picoA_per_millimolar_4).
* CONSTANTS[26] is d_NaCa in component Na_Ca_ion_exchanger_current (per_millimolar_4).
* CONSTANTS[27] is gamma in component Na_Ca_ion_exchanger_current (dimensionless).
* CONSTANTS[28] is phi_Na_en in component intracellular_ion_concentrations (picoA).
* CONSTANTS[29] is Vol_i in component intracellular_ion_concentrations (nanolitre).
* CONSTANTS[49] is Vol_d in component intracellular_ion_concentrations (nanolitre).
* ALGEBRAIC[42] is i_di in component intracellular_ion_concentrations (picoA).
* CONSTANTS[30] is tau_di in component intracellular_ion_concentrations (second).
* ALGEBRAIC[46] is i_up in component Ca_handling_by_the_SR (picoA).
* ALGEBRAIC[48] is i_rel in component Ca_handling_by_the_SR (picoA).
* ALGEBRAIC[43] is dOCdt in component intracellular_Ca_buffering (per_second).
* ALGEBRAIC[44] is dOTCdt in component intracellular_Ca_buffering (per_second).
* ALGEBRAIC[45] is dOTMgCdt in component intracellular_Ca_buffering (per_second).
* STATES[20] is O_C in component intracellular_Ca_buffering (dimensionless).
* STATES[21] is O_TC in component intracellular_Ca_buffering (dimensionless).
* STATES[22] is O_TMgC in component intracellular_Ca_buffering (dimensionless).
* STATES[23] is O_TMgMg in component intracellular_Ca_buffering (dimensionless).
* CONSTANTS[31] is Mg_i in component intracellular_Ca_buffering (millimolar).
* CONSTANTS[50] is Vol_c in component cleft_space_ion_concentrations (nanolitre).
* CONSTANTS[32] is tau_Na in component cleft_space_ion_concentrations (second).
* CONSTANTS[33] is tau_K in component cleft_space_ion_concentrations (second).
* CONSTANTS[34] is tau_Ca in component cleft_space_ion_concentrations (second).
* CONSTANTS[35] is Na_b in component cleft_space_ion_concentrations (millimolar).
* CONSTANTS[36] is Ca_b in component cleft_space_ion_concentrations (millimolar).
* CONSTANTS[37] is K_b in component cleft_space_ion_concentrations (millimolar).
* ALGEBRAIC[47] is i_tr in component Ca_handling_by_the_SR (picoA).
* CONSTANTS[38] is I_up_max in component Ca_handling_by_the_SR (picoA).
* CONSTANTS[39] is k_cyca in component Ca_handling_by_the_SR (millimolar).
* CONSTANTS[40] is k_srca in component Ca_handling_by_the_SR (millimolar).
* CONSTANTS[41] is k_xcs in component Ca_handling_by_the_SR (dimensionless).
* CONSTANTS[42] is alpha_rel in component Ca_handling_by_the_SR (picoA_per_millimolar).
* STATES[24] is Ca_rel in component Ca_handling_by_the_SR (millimolar).
* STATES[25] is Ca_up in component Ca_handling_by_the_SR (millimolar).
* CONSTANTS[43] is Vol_up in component Ca_handling_by_the_SR (nanolitre).
* CONSTANTS[44] is Vol_rel in component Ca_handling_by_the_SR (nanolitre).
* ALGEBRAIC[11] is r_act in component Ca_handling_by_the_SR (per_second).
* ALGEBRAIC[25] is r_inact in component Ca_handling_by_the_SR (per_second).
* CONSTANTS[45] is r_recov in component Ca_handling_by_the_SR (per_second).
* STATES[26] is O_Calse in component Ca_handling_by_the_SR (dimensionless).
* STATES[27] is F1 in component Ca_handling_by_the_SR (dimensionless).
* STATES[28] is F2 in component Ca_handling_by_the_SR (dimensionless).
* CONSTANTS[46] is tau_tr in component Ca_handling_by_the_SR (second).
* CONSTANTS[47] is k_rel_i in component Ca_handling_by_the_SR (millimolar).
* CONSTANTS[48] is k_rel_d in component Ca_handling_by_the_SR (millimolar).
* RATES[0] is d/dt V in component membrane (millivolt).
* RATES[3] is d/dt m in component sodium_current_m_gate (dimensionless).
* RATES[4] is d/dt h1 in component sodium_current_h1_gate (dimensionless).
* RATES[5] is d/dt h2 in component sodium_current_h2_gate (dimensionless).
* RATES[7] is d/dt d_L in component L_type_Ca_channel_d_L_gate (dimensionless).
* RATES[8] is d/dt f_L_1 in component L_type_Ca_channel_f_L1_gate (dimensionless).
* RATES[9] is d/dt f_L_2 in component L_type_Ca_channel_f_L2_gate (dimensionless).
* RATES[12] is d/dt r in component Ca_independent_transient_outward_K_current_r_gate (dimensionless).
* RATES[13] is d/dt s in component Ca_independent_transient_outward_K_current_s_gate (dimensionless).
* RATES[14] is d/dt r_sus in component sustained_outward_K_current_r_sus_gate (dimensionless).
* RATES[15] is d/dt s_sus in component sustained_outward_K_current_s_sus_gate (dimensionless).
* RATES[16] is d/dt n in component delayed_rectifier_K_currents_n_gate (dimensionless).
* RATES[17] is d/dt p_a in component delayed_rectifier_K_currents_pa_gate (dimensionless).
* RATES[2] is d/dt Na_i in component intracellular_ion_concentrations (millimolar).
* RATES[11] is d/dt K_i in component intracellular_ion_concentrations (millimolar).
* RATES[19] is d/dt Ca_i in component intracellular_ion_concentrations (millimolar).
* RATES[6] is d/dt Ca_d in component intracellular_ion_concentrations (millimolar).
* RATES[20] is d/dt O_C in component intracellular_Ca_buffering (dimensionless).
* RATES[21] is d/dt O_TC in component intracellular_Ca_buffering (dimensionless).
* RATES[22] is d/dt O_TMgC in component intracellular_Ca_buffering (dimensionless).
* RATES[23] is d/dt O_TMgMg in component intracellular_Ca_buffering (dimensionless).
* RATES[1] is d/dt Na_c in component cleft_space_ion_concentrations (millimolar).
* RATES[10] is d/dt K_c in component cleft_space_ion_concentrations (millimolar).
* RATES[18] is d/dt Ca_c in component cleft_space_ion_concentrations (millimolar).
* RATES[26] is d/dt O_Calse in component Ca_handling_by_the_SR (dimensionless).
* RATES[24] is d/dt Ca_rel in component Ca_handling_by_the_SR (millimolar).
* RATES[25] is d/dt Ca_up in component Ca_handling_by_the_SR (millimolar).
* RATES[27] is d/dt F1 in component Ca_handling_by_the_SR (dimensionless).
* RATES[28] is d/dt F2 in component Ca_handling_by_the_SR (dimensionless).
*/
void
initConsts(double* CONSTANTS, double* RATES, double *STATES)
{
STATES[0] = -74.2525;
CONSTANTS[0] = 8314;
CONSTANTS[1] = 306.15;
CONSTANTS[2] = 96487;
CONSTANTS[3] = 0.05;
CONSTANTS[4] = 0.1;
CONSTANTS[5] = 100000000;
CONSTANTS[6] = 1;
CONSTANTS[7] = 0.006;
CONSTANTS[8] = -280;
CONSTANTS[9] = 0.0016;
STATES[1] = 130.011;
STATES[2] = 8.5547;
STATES[3] = 0.0032017;
STATES[4] = 0.8814;
STATES[5] = 0.8742;
CONSTANTS[10] = 6.75;
CONSTANTS[11] = 60;
CONSTANTS[12] = 0.025;
STATES[6] = 7.2495e-5;
STATES[7] = 1.3005e-5;
STATES[8] = 0.9986;
STATES[9] = 0.9986;
CONSTANTS[13] = 7.5;
STATES[10] = 5.3581;
STATES[11] = 129.435;
STATES[12] = 0.0010678;
STATES[13] = 0.949;
CONSTANTS[14] = 2.75;
STATES[14] = 0.00015949;
STATES[15] = 0.9912;
CONSTANTS[15] = 1;
CONSTANTS[16] = 0.5;
STATES[16] = 0.0048357;
STATES[17] = 0.0001;
CONSTANTS[17] = 3;
CONSTANTS[18] = 0.060599;
CONSTANTS[19] = 0.078681;
STATES[18] = 1.8147;
STATES[19] = 6.729e-5;
CONSTANTS[20] = 1;
CONSTANTS[21] = 11;
CONSTANTS[22] = 70.8253;
CONSTANTS[23] = 4;
CONSTANTS[24] = 0.0002;
CONSTANTS[25] = 0.0374842;
CONSTANTS[26] = 0.0003;
CONSTANTS[27] = 0.45;
CONSTANTS[28] = -1.68;
CONSTANTS[29] = 0.005884;
CONSTANTS[30] = 0.01;
STATES[20] = 0.0275;
STATES[21] = 0.0133;
STATES[22] = 0.1961;
STATES[23] = 0.7094;
CONSTANTS[31] = 2.5;
CONSTANTS[32] = 14.3;
CONSTANTS[33] = 10;
CONSTANTS[34] = 24.7;
CONSTANTS[35] = 130;
CONSTANTS[36] = 1.8;
CONSTANTS[37] = 5.4;
CONSTANTS[38] = 2800;
CONSTANTS[39] = 0.0003;
CONSTANTS[40] = 0.5;
CONSTANTS[41] = 0.4;
CONSTANTS[42] = 200000;
STATES[24] = 0.6465;
STATES[25] = 0.6646;
CONSTANTS[43] = 0.0003969;
CONSTANTS[44] = 4.41e-5;
CONSTANTS[45] = 0.815;
STATES[26] = 0.4369;
STATES[27] = 0.4284;
STATES[28] = 0.0028;
CONSTANTS[46] = 0.01;
CONSTANTS[47] = 0.0003;
CONSTANTS[48] = 0.003;
CONSTANTS[49] = 0.0200000*CONSTANTS[29];
CONSTANTS[50] = 0.136000*CONSTANTS[29];
}
void
computeRates(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
RATES[23] = 2000.00*CONSTANTS[31]*((1.00000 - STATES[22]) - STATES[23]) - 666.000*STATES[23];
ALGEBRAIC[11] = 203.800*(pow(STATES[19]/(STATES[19]+CONSTANTS[47]), 4.00000)+pow(STATES[6]/(STATES[6]+CONSTANTS[48]), 4.00000));
RATES[27] = CONSTANTS[45]*((1.00000 - STATES[27]) - STATES[28]) - ALGEBRAIC[11]*STATES[27];
ALGEBRAIC[1] = 1.00000/(1.00000+exp((STATES[0]+27.1200)/- 8.21000));
ALGEBRAIC[13] = 4.20000e-05*exp(- pow((STATES[0]+25.5700)/28.8000, 2.00000))+2.40000e-05;
RATES[3] = (ALGEBRAIC[1] - STATES[3])/ALGEBRAIC[13];
ALGEBRAIC[2] = 1.00000/(1.00000+exp((STATES[0]+63.6000)/5.30000));
ALGEBRAIC[14] = 0.0300000/(1.00000+exp((STATES[0]+35.1000)/3.20000))+0.000300000;
RATES[4] = (ALGEBRAIC[2] - STATES[4])/ALGEBRAIC[14];
ALGEBRAIC[15] = 0.120000/(1.00000+exp((STATES[0]+35.1000)/3.20000))+0.00300000;
RATES[5] = (ALGEBRAIC[2] - STATES[5])/ALGEBRAIC[15];
ALGEBRAIC[3] = 1.00000/(1.00000+exp((STATES[0]+9.00000)/- 5.80000));
ALGEBRAIC[16] = 0.00270000*exp(- pow((STATES[0]+35.0000)/30.0000, 2.00000))+0.00200000;
RATES[7] = (ALGEBRAIC[3] - STATES[7])/ALGEBRAIC[16];
ALGEBRAIC[4] = 1.00000/(1.00000+exp((STATES[0]+27.4000)/7.10000));
ALGEBRAIC[17] = 0.161000*exp(- pow((STATES[0]+40.0000)/14.4000, 2.00000))+0.0100000;
RATES[8] = (ALGEBRAIC[4] - STATES[8])/ALGEBRAIC[17];
ALGEBRAIC[18] = 1.33230*exp(- pow((STATES[0]+40.0000)/14.2000, 2.00000))+0.0626000;
RATES[9] = (ALGEBRAIC[4] - STATES[9])/ALGEBRAIC[18];
ALGEBRAIC[19] = 0.00350000*exp(- pow(STATES[0]/30.0000, 2.00000))+0.00150000;
ALGEBRAIC[5] = 1.00000/(1.00000+exp((STATES[0] - 1.00000)/- 11.0000));
RATES[12] = (ALGEBRAIC[5] - STATES[12])/ALGEBRAIC[19];
ALGEBRAIC[20] = 0.481200*exp(- pow((STATES[0]+52.4500)/14.9700, 2.00000))+0.0141400;
ALGEBRAIC[6] = 1.00000/(1.00000+exp((STATES[0]+40.5000)/11.5000));
RATES[13] = (ALGEBRAIC[6] - STATES[13])/ALGEBRAIC[20];
ALGEBRAIC[21] = 0.00900000/(1.00000+exp((STATES[0]+5.00000)/12.0000))+0.000500000;
ALGEBRAIC[7] = 1.00000/(1.00000+exp((STATES[0]+4.30000)/- 8.00000));
RATES[14] = (ALGEBRAIC[7] - STATES[14])/ALGEBRAIC[21];
ALGEBRAIC[22] = 0.0470000/(1.00000+exp((STATES[0]+60.0000)/10.0000))+0.300000;
ALGEBRAIC[8] = 0.400000/(1.00000+exp((STATES[0]+20.0000)/10.0000))+0.600000;
RATES[15] = (ALGEBRAIC[8] - STATES[15])/ALGEBRAIC[22];
ALGEBRAIC[23] = 0.700000+ 0.400000*exp(- pow((STATES[0] - 20.0000)/20.0000, 2.00000));
ALGEBRAIC[9] = 1.00000/(1.00000+exp((STATES[0] - 19.9000)/- 12.7000));
RATES[16] = (ALGEBRAIC[9] - STATES[16])/ALGEBRAIC[23];
ALGEBRAIC[24] = 0.0311800+ 0.217180*exp(- pow((STATES[0]+20.1376)/22.1996, 2.00000));
ALGEBRAIC[10] = 1.00000/(1.00000+exp((STATES[0]+15.0000)/- 6.00000));
RATES[17] = (ALGEBRAIC[10] - STATES[17])/ALGEBRAIC[24];
ALGEBRAIC[25] = 33.9600+ 339.600*pow(STATES[19]/(STATES[19]+CONSTANTS[47]), 4.00000);
RATES[28] = ALGEBRAIC[11]*STATES[27] - ALGEBRAIC[25]*STATES[28];
ALGEBRAIC[29] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(STATES[10]/STATES[11]);
ALGEBRAIC[30] = CONSTANTS[13]*STATES[12]*STATES[13]*(STATES[0] - ALGEBRAIC[29]);
ALGEBRAIC[31] = CONSTANTS[14]*STATES[14]*STATES[15]*(STATES[0] - ALGEBRAIC[29]);
ALGEBRAIC[35] = ( CONSTANTS[17]*pow(STATES[10]/1.00000, 0.445700)*(STATES[0] - ALGEBRAIC[29]))/(1.00000+exp(( 1.50000*((STATES[0] - ALGEBRAIC[29])+3.60000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[33] = 1.00000/(1.00000+exp((STATES[0]+55.0000)/24.0000));
ALGEBRAIC[34] = CONSTANTS[16]*STATES[17]*ALGEBRAIC[33]*(STATES[0] - ALGEBRAIC[29]);
ALGEBRAIC[32] = CONSTANTS[15]*STATES[16]*(STATES[0] - ALGEBRAIC[29]);
ALGEBRAIC[39] = ( (( (( CONSTANTS[22]*STATES[10])/(STATES[10]+CONSTANTS[20]))*pow(STATES[2], 1.50000))/(pow(STATES[2], 1.50000)+pow(CONSTANTS[21], 1.50000)))*(STATES[0]+150.000))/(STATES[0]+200.000);
RATES[11] = - ((ALGEBRAIC[30]+ALGEBRAIC[31]+ALGEBRAIC[35]+ALGEBRAIC[34]+ALGEBRAIC[32]) - 2.00000*ALGEBRAIC[39])/( CONSTANTS[29]*CONSTANTS[2]);
RATES[10] = (CONSTANTS[37] - STATES[10])/CONSTANTS[33]+((ALGEBRAIC[30]+ALGEBRAIC[31]+ALGEBRAIC[35]+ALGEBRAIC[34]+ALGEBRAIC[32]) - 2.00000*ALGEBRAIC[39])/( CONSTANTS[50]*CONSTANTS[2]);
ALGEBRAIC[12] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(STATES[1]/STATES[2]);
ALGEBRAIC[26] = ( (( CONSTANTS[9]*pow(STATES[3], 3.00000)*( 0.900000*STATES[4]+ 0.100000*STATES[5])*STATES[1]*STATES[0]*pow(CONSTANTS[2], 2.00000))/( CONSTANTS[0]*CONSTANTS[1]))*(exp(( (STATES[0] - ALGEBRAIC[12])*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - 1.00000))/(exp(( STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - 1.00000);
ALGEBRAIC[27] = STATES[6]/(STATES[6]+CONSTANTS[12]);
ALGEBRAIC[28] = CONSTANTS[10]*STATES[7]*( ALGEBRAIC[27]*STATES[8]+ (1.00000 - ALGEBRAIC[27])*STATES[9])*(STATES[0] - CONSTANTS[11]);
ALGEBRAIC[36] = CONSTANTS[18]*(STATES[0] - ALGEBRAIC[12]);
ALGEBRAIC[37] = (( CONSTANTS[0]*CONSTANTS[1])/( 2.00000*CONSTANTS[2]))*log(STATES[18]/STATES[19]);
ALGEBRAIC[38] = CONSTANTS[19]*(STATES[0] - ALGEBRAIC[37]);
ALGEBRAIC[40] = ( CONSTANTS[23]*STATES[19])/(STATES[19]+CONSTANTS[24]);
ALGEBRAIC[41] = ( CONSTANTS[25]*( pow(STATES[2], 3.00000)*STATES[18]*exp(( CONSTANTS[27]*CONSTANTS[2]*STATES[0])/( CONSTANTS[0]*CONSTANTS[1])) - pow(STATES[1], 3.00000)*STATES[19]*exp(( (CONSTANTS[27] - 1.00000)*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))/(1.00000+ CONSTANTS[26]*( pow(STATES[1], 3.00000)*STATES[19]+ pow(STATES[2], 3.00000)*STATES[18]));
ALGEBRAIC[0] = (VOI>=CONSTANTS[4]&&VOI<=CONSTANTS[5]&&(VOI - CONSTANTS[4]) - floor((VOI - CONSTANTS[4])/CONSTANTS[6])*CONSTANTS[6]<=CONSTANTS[7] ? CONSTANTS[8] : 0.00000);
RATES[0] = (- 1.00000/CONSTANTS[3])*(ALGEBRAIC[0]+ALGEBRAIC[26]+ALGEBRAIC[28]+ALGEBRAIC[30]+ALGEBRAIC[31]+ALGEBRAIC[35]+ALGEBRAIC[34]+ALGEBRAIC[32]+ALGEBRAIC[36]+ALGEBRAIC[38]+ALGEBRAIC[39]+ALGEBRAIC[40]+ALGEBRAIC[41]);
RATES[2] = - (ALGEBRAIC[26]+ALGEBRAIC[36]+ 3.00000*ALGEBRAIC[39]+ 3.00000*ALGEBRAIC[41]+CONSTANTS[28])/( CONSTANTS[29]*CONSTANTS[2]);
RATES[1] = (CONSTANTS[35] - STATES[1])/CONSTANTS[32]+(ALGEBRAIC[26]+ALGEBRAIC[36]+ 3.00000*ALGEBRAIC[39]+ 3.00000*ALGEBRAIC[41]+CONSTANTS[28])/( CONSTANTS[50]*CONSTANTS[2]);
RATES[18] = (CONSTANTS[36] - STATES[18])/CONSTANTS[34]+((ALGEBRAIC[28]+ALGEBRAIC[38]+ALGEBRAIC[40]) - 2.00000*ALGEBRAIC[41])/( 2.00000*CONSTANTS[50]*CONSTANTS[2]);
RATES[20] = 200000.*STATES[19]*(1.00000 - STATES[20]) - 476.000*STATES[20];
ALGEBRAIC[42] = ( (STATES[6] - STATES[19])*2.00000*CONSTANTS[2]*CONSTANTS[49])/CONSTANTS[30];
RATES[6] = - (ALGEBRAIC[28]+ALGEBRAIC[42])/( 2.00000*CONSTANTS[49]*CONSTANTS[2]);
RATES[21] = 78400.0*STATES[19]*(1.00000 - STATES[21]) - 392.000*STATES[21];
RATES[22] = 200000.*STATES[19]*((1.00000 - STATES[22]) - STATES[23]) - 6.60000*STATES[22];
ALGEBRAIC[46] = ( CONSTANTS[38]*(STATES[19]/CONSTANTS[39] - ( pow(CONSTANTS[41], 2.00000)*STATES[25])/CONSTANTS[40]))/((STATES[19]+CONSTANTS[39])/CONSTANTS[39]+( CONSTANTS[41]*(STATES[25]+CONSTANTS[40]))/CONSTANTS[40]);
ALGEBRAIC[47] = ( (STATES[25] - STATES[24])*2.00000*CONSTANTS[2]*CONSTANTS[44])/CONSTANTS[46];
RATES[25] = (ALGEBRAIC[46] - ALGEBRAIC[47])/( 2.00000*CONSTANTS[43]*CONSTANTS[2]);
ALGEBRAIC[48] = CONSTANTS[42]*pow(STATES[28]/(STATES[28]+0.250000), 2.00000)*(STATES[24] - STATES[19]);
ALGEBRAIC[43] = RATES[20];
ALGEBRAIC[44] = RATES[21];
ALGEBRAIC[45] = RATES[22];
RATES[19] = - ((((- ALGEBRAIC[42]+ALGEBRAIC[38]+ALGEBRAIC[40]) - 2.00000*ALGEBRAIC[41])+ALGEBRAIC[46]) - ALGEBRAIC[48])/( 2.00000*CONSTANTS[29]*CONSTANTS[2]) - ( 0.0800000*ALGEBRAIC[44]+ 0.160000*ALGEBRAIC[45]+ 0.0450000*ALGEBRAIC[43]);
RATES[26] = 480.000*STATES[24]*(1.00000 - STATES[26]) - 400.000*STATES[26];
RATES[24] = (ALGEBRAIC[47] - ALGEBRAIC[48])/( 2.00000*CONSTANTS[44]*CONSTANTS[2]) - 31.0000*RATES[26];
}
void
computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[11] = 203.800*(pow(STATES[19]/(STATES[19]+CONSTANTS[47]), 4.00000)+pow(STATES[6]/(STATES[6]+CONSTANTS[48]), 4.00000));
ALGEBRAIC[1] = 1.00000/(1.00000+exp((STATES[0]+27.1200)/- 8.21000));
ALGEBRAIC[13] = 4.20000e-05*exp(- pow((STATES[0]+25.5700)/28.8000, 2.00000))+2.40000e-05;
ALGEBRAIC[2] = 1.00000/(1.00000+exp((STATES[0]+63.6000)/5.30000));
ALGEBRAIC[14] = 0.0300000/(1.00000+exp((STATES[0]+35.1000)/3.20000))+0.000300000;
ALGEBRAIC[15] = 0.120000/(1.00000+exp((STATES[0]+35.1000)/3.20000))+0.00300000;
ALGEBRAIC[3] = 1.00000/(1.00000+exp((STATES[0]+9.00000)/- 5.80000));
ALGEBRAIC[16] = 0.00270000*exp(- pow((STATES[0]+35.0000)/30.0000, 2.00000))+0.00200000;
ALGEBRAIC[4] = 1.00000/(1.00000+exp((STATES[0]+27.4000)/7.10000));
ALGEBRAIC[17] = 0.161000*exp(- pow((STATES[0]+40.0000)/14.4000, 2.00000))+0.0100000;
ALGEBRAIC[18] = 1.33230*exp(- pow((STATES[0]+40.0000)/14.2000, 2.00000))+0.0626000;
ALGEBRAIC[19] = 0.00350000*exp(- pow(STATES[0]/30.0000, 2.00000))+0.00150000;
ALGEBRAIC[5] = 1.00000/(1.00000+exp((STATES[0] - 1.00000)/- 11.0000));
ALGEBRAIC[20] = 0.481200*exp(- pow((STATES[0]+52.4500)/14.9700, 2.00000))+0.0141400;
ALGEBRAIC[6] = 1.00000/(1.00000+exp((STATES[0]+40.5000)/11.5000));
ALGEBRAIC[21] = 0.00900000/(1.00000+exp((STATES[0]+5.00000)/12.0000))+0.000500000;
ALGEBRAIC[7] = 1.00000/(1.00000+exp((STATES[0]+4.30000)/- 8.00000));
ALGEBRAIC[22] = 0.0470000/(1.00000+exp((STATES[0]+60.0000)/10.0000))+0.300000;
ALGEBRAIC[8] = 0.400000/(1.00000+exp((STATES[0]+20.0000)/10.0000))+0.600000;
ALGEBRAIC[23] = 0.700000+ 0.400000*exp(- pow((STATES[0] - 20.0000)/20.0000, 2.00000));
ALGEBRAIC[9] = 1.00000/(1.00000+exp((STATES[0] - 19.9000)/- 12.7000));
ALGEBRAIC[24] = 0.0311800+ 0.217180*exp(- pow((STATES[0]+20.1376)/22.1996, 2.00000));
ALGEBRAIC[10] = 1.00000/(1.00000+exp((STATES[0]+15.0000)/- 6.00000));
ALGEBRAIC[25] = 33.9600+ 339.600*pow(STATES[19]/(STATES[19]+CONSTANTS[47]), 4.00000);
ALGEBRAIC[29] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(STATES[10]/STATES[11]);
ALGEBRAIC[30] = CONSTANTS[13]*STATES[12]*STATES[13]*(STATES[0] - ALGEBRAIC[29]);
ALGEBRAIC[31] = CONSTANTS[14]*STATES[14]*STATES[15]*(STATES[0] - ALGEBRAIC[29]);
ALGEBRAIC[35] = ( CONSTANTS[17]*pow(STATES[10]/1.00000, 0.445700)*(STATES[0] - ALGEBRAIC[29]))/(1.00000+exp(( 1.50000*((STATES[0] - ALGEBRAIC[29])+3.60000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[33] = 1.00000/(1.00000+exp((STATES[0]+55.0000)/24.0000));
ALGEBRAIC[34] = CONSTANTS[16]*STATES[17]*ALGEBRAIC[33]*(STATES[0] - ALGEBRAIC[29]);
ALGEBRAIC[32] = CONSTANTS[15]*STATES[16]*(STATES[0] - ALGEBRAIC[29]);
ALGEBRAIC[39] = ( (( (( CONSTANTS[22]*STATES[10])/(STATES[10]+CONSTANTS[20]))*pow(STATES[2], 1.50000))/(pow(STATES[2], 1.50000)+pow(CONSTANTS[21], 1.50000)))*(STATES[0]+150.000))/(STATES[0]+200.000);
ALGEBRAIC[12] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(STATES[1]/STATES[2]);
ALGEBRAIC[26] = ( (( CONSTANTS[9]*pow(STATES[3], 3.00000)*( 0.900000*STATES[4]+ 0.100000*STATES[5])*STATES[1]*STATES[0]*pow(CONSTANTS[2], 2.00000))/( CONSTANTS[0]*CONSTANTS[1]))*(exp(( (STATES[0] - ALGEBRAIC[12])*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - 1.00000))/(exp(( STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - 1.00000);
ALGEBRAIC[27] = STATES[6]/(STATES[6]+CONSTANTS[12]);
ALGEBRAIC[28] = CONSTANTS[10]*STATES[7]*( ALGEBRAIC[27]*STATES[8]+ (1.00000 - ALGEBRAIC[27])*STATES[9])*(STATES[0] - CONSTANTS[11]);
ALGEBRAIC[36] = CONSTANTS[18]*(STATES[0] - ALGEBRAIC[12]);
ALGEBRAIC[37] = (( CONSTANTS[0]*CONSTANTS[1])/( 2.00000*CONSTANTS[2]))*log(STATES[18]/STATES[19]);
ALGEBRAIC[38] = CONSTANTS[19]*(STATES[0] - ALGEBRAIC[37]);
ALGEBRAIC[40] = ( CONSTANTS[23]*STATES[19])/(STATES[19]+CONSTANTS[24]);
ALGEBRAIC[41] = ( CONSTANTS[25]*( pow(STATES[2], 3.00000)*STATES[18]*exp(( CONSTANTS[27]*CONSTANTS[2]*STATES[0])/( CONSTANTS[0]*CONSTANTS[1])) - pow(STATES[1], 3.00000)*STATES[19]*exp(( (CONSTANTS[27] - 1.00000)*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))/(1.00000+ CONSTANTS[26]*( pow(STATES[1], 3.00000)*STATES[19]+ pow(STATES[2], 3.00000)*STATES[18]));
ALGEBRAIC[0] = (VOI>=CONSTANTS[4]&&VOI<=CONSTANTS[5]&&(VOI - CONSTANTS[4]) - floor((VOI - CONSTANTS[4])/CONSTANTS[6])*CONSTANTS[6]<=CONSTANTS[7] ? CONSTANTS[8] : 0.00000);
ALGEBRAIC[42] = ( (STATES[6] - STATES[19])*2.00000*CONSTANTS[2]*CONSTANTS[49])/CONSTANTS[30];
ALGEBRAIC[46] = ( CONSTANTS[38]*(STATES[19]/CONSTANTS[39] - ( pow(CONSTANTS[41], 2.00000)*STATES[25])/CONSTANTS[40]))/((STATES[19]+CONSTANTS[39])/CONSTANTS[39]+( CONSTANTS[41]*(STATES[25]+CONSTANTS[40]))/CONSTANTS[40]);
ALGEBRAIC[47] = ( (STATES[25] - STATES[24])*2.00000*CONSTANTS[2]*CONSTANTS[44])/CONSTANTS[46];
ALGEBRAIC[48] = CONSTANTS[42]*pow(STATES[28]/(STATES[28]+0.250000), 2.00000)*(STATES[24] - STATES[19]);
ALGEBRAIC[43] = RATES[20];
ALGEBRAIC[44] = RATES[21];
ALGEBRAIC[45] = RATES[22];
}