Sedaghat, Sherman and Quon's 2002 mathematical model of metabolic insulin signaling pathways.
keyword
The new version of this model has been re-coded to remove the reaction element and replace it with a simple MathML description of the model reaction kinetics. This is thought to be truer to the original publication, and information regarding the enzyme kinetics etc will later be added to the metadata through use of an ontology.
concentration of phosphorylated once-bound surface receptors
x5
Catherine
May
Lloyd
insulin
signal transduction
metabolism
Lloyd
Catherine
May
x3
concentration of unphosphorylated once-bound surface receptors
The University of Auckland
Auckland Bioengineering Institute
x16
percentage of unactivated Akt
x12
concentration of tyrosine-phosphorylated IRS-1/activated PI 3-kinase complex
This is the CellML descripition of Sedaghat, Sherman and Quon's 2002
mathematical model of metabolic insulin signaling pathways.
x18
percentage of unactivated PKC-zeta
x15
percentage of PI(3,4)P2 out of the total lipid population
concentration of unbound unphosphorylated intracellular receptors
x6
Michael
Quon
J
12376338
Ahmad
R
Sedaghat
c.lloyd@auckland.ac.nz
American Journal of Physiology
x14
percentage of PI(4,5)P2 out of the total lipid population
Arthur
Sherman
A mathematical model of metabolic insulin signaling pathways (without feedback)
The University of Auckland, Bioengineering Institute
2007-06-05T10:44:09+12:00
A mathematical model of metabolic insulin signaling pathways
E1084
283
E1101
percentage of activated Akt
x17
concentration of unphosphorylated IRS-1
x9
insulin input
x1
x20
percentage of intracellular GLUT4
Catherine Lloyd
x4
concentration of phosphorylated twice-bound surface receptors
x8
concentration of phosphorylated once-bound intracellular receptors
x10
concentration of tyrosine-phosphorylated IRS-1
2007-05-30T00:00:00+00:00
x7
concentration of phosphorylated twice-bound intracellular receptors
x11
concentration of unactivated PI 3-kinase
0.01
x2
concentration of unbound surface insulin receptors
x19
percentage of activated PKC-zeta
percentage of PI(3,4,5)P3 out of the total lipid population
x13
percentage of cell surface GLUT4
x21
2002-11