https://staging.physiomeproject.org/w/hnielsen/kummer_2000 en-us We present a new model for calcium oscillations based on experiments in hepatocytes. The model considers feedback inhibition on the initial agonist receptor complex by calcium and activated phospholipase C, as well as receptor type-dependent self-enhanced behavior of the activated G(alpha) subunit. It is able to show simple periodic oscillations and periodic bursting, and it is the first model to display chaotic bursting in response to agonist stimulations. Moreover, our model offers a possible explanation for the differences in dynamic behavior observed in response to different agonists in hepatocytes. https://staging.physiomeproject.org/w/hnielsen/kummer_2000/@@file/74efc6f67a1e1c233d0b5a2645051f6e932079bf Added image in HTML file Hanne Nielsen 2011-08-23 https://staging.physiomeproject.org/w/hnielsen/kummer_2000/@@file/c9fab2fc73fac6a5ff947841604494184b828ab7 Added clickable SVG to sessions and a xul file Hanne Nielsen 2011-08-23 https://staging.physiomeproject.org/w/hnielsen/kummer_2000/@@file/146aaa791f91cffdf00db94a56fc3a5da7c38ec2 Added HTML file Hanne Nielsen 2011-08-02 https://staging.physiomeproject.org/w/hnielsen/kummer_2000/@@file/9c9ebfb35414e80532eb6c2068fb8f4d50c843d1 Removed extra cellml file Hanne Nielsen 2011-08-01 https://staging.physiomeproject.org/w/hnielsen/kummer_2000/@@file/45f59c3924e3fff5babc452f0062fd491205c381 Added rdf tags to models and corrected a missing minus sign from equation 4 Hanne Nielsen 2011-07-29 https://staging.physiomeproject.org/w/hnielsen/kummer_2000/@@file/7df779b29d4f8394f1599e77dd252fc22de23392 Added cellml files with annotations and updated session files. 1a refers to eqns 1-4, 1b to eqns 2-5 and 1c to eqns 6-8 Hanne Nielsen 2011-07-22 https://staging.physiomeproject.org/w/hnielsen/kummer_2000/@@file/3760652ac7bc50ce0ca2ffa662538972bae70f8f Added cellml file kummer_2000_1c dealing with equations 4-6 and figure 7 from the paper Hanne Nielsen 2011-07-19 https://staging.physiomeproject.org/w/hnielsen/kummer_2000/@@file/4edf6fe8029cd0f90a1a8e124c5a1c7842b3fb14 Added cellml file kummer_2000_1b dealing with equations 2-5 from the paper Hanne Nielsen 2011-07-19 https://staging.physiomeproject.org/w/hnielsen/kummer_2000/@@file/8dd6e439e9b87aa0c7be68fa691ab4b8e311e72e Added session file with graph for figure 3, graph a. No metadata in session file Hanne Nielsen 2011-07-19 https://staging.physiomeproject.org/w/hnielsen/kummer_2000/@@file/e70017b7d4c39f8911a400699e848d2a33fa66a1 Added cellMl file for figure 3, graph a using equations 1-4 Hanne Nielsen 2011-07-18