- Author:
- Hanne Nielsen <hnie010@aucklanduni.ac.nz>
- Date:
- 2011-07-22 15:29:51+12:00
- Desc:
- Added cellml files with annotations and updated session files. 1a refers to eqns 1-4, 1b to eqns 2-5 and 1c to eqns 6-8
- Permanent Source URI:
- https://staging.physiomeproject.org/w/hnielsen/kummer_2000/rawfile/7df779b29d4f8394f1599e77dd252fc22de23392/kummer_2000_1c.cellml
<?xml version="1.0"?>
<!--
This CellML file was generated on 7/20/2011 at 2:17:56 at PM using:
COR (0.9.31.1409)
Copyright 2002-2011 Dr Alan Garny
http://cor.physiol.ox.ac.uk/ - cor@physiol.ox.ac.uk
CellML 1.0 was used to generate this model
http://www.cellml.org/
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<units name="micromole">
<unit prefix="micro" units="mole"/>
</units>
<units name="micromolar">
<unit units="micromole"/>
<unit exponent="-1" units="litre"/>
</units>
<component name="environment">
<variable cmeta:id="environment_time" name="time" public_interface="out" units="second"/>
</component>
<component name="a">
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<variable name="k1" public_interface="in" units="dimensionless"/>
<variable name="k2" public_interface="in" units="dimensionless"/>
<variable name="k3" public_interface="in" units="dimensionless"/>
<variable name="b" public_interface="in" units="micromolar"/>
<variable name="c" public_interface="in" units="micromolar"/>
<variable name="K4" public_interface="in" units="dimensionless"/>
<variable name="k5" public_interface="in" units="dimensionless"/>
<variable name="K6" public_interface="in" units="dimensionless"/>
<variable name="time" public_interface="in" units="second"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>a</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<plus/>
<ci>k1</ci>
<apply>
<times/>
<ci>k2</ci>
<ci>a</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>k3</ci>
<ci>a</ci>
<ci>b</ci>
</apply>
<apply>
<plus/>
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<ci>K4</ci>
</apply>
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<apply>
<divide/>
<apply>
<times/>
<ci>k5</ci>
<ci>a</ci>
<ci>c</ci>
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<apply>
<plus/>
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<ci>K6</ci>
</apply>
</apply>
</apply>
</apply>
</math>
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<component name="b">
<variable cmeta:id="b_b" initial_value="0.01" name="b" public_interface="out" units="micromolar"/>
<variable name="k7" public_interface="in" units="dimensionless"/>
<variable name="a" public_interface="in" units="micromolar"/>
<variable name="k8" public_interface="in" units="dimensionless"/>
<variable name="K9" public_interface="in" units="dimensionless"/>
<variable name="time" public_interface="in" units="second"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>b</ci>
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<apply>
<minus/>
<apply>
<times/>
<ci>k7</ci>
<ci>a</ci>
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<apply>
<divide/>
<apply>
<times/>
<ci>k8</ci>
<ci>b</ci>
</apply>
<apply>
<plus/>
<ci>K9</ci>
<ci>b</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="c">
<variable cmeta:id="c_c" initial_value="0.01" name="c" public_interface="out" units="micromolar"/>
<variable name="k10" public_interface="in" units="dimensionless"/>
<variable name="a" public_interface="in" units="micromolar"/>
<variable name="k11" public_interface="in" units="dimensionless"/>
<variable name="K12" public_interface="in" units="dimensionless"/>
<variable name="time" public_interface="in" units="second"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
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</bvar>
<ci>c</ci>
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<apply>
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<apply>
<divide/>
<apply>
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<ci>c</ci>
</apply>
<apply>
<plus/>
<ci>c</ci>
<ci>K12</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="model_parameters">
<variable initial_value="0.212" name="k1" public_interface="out" units="dimensionless"/>
<variable initial_value="2.9259" name="k2" public_interface="out" units="dimensionless"/>
<variable initial_value="1.52" name="k3" public_interface="out" units="dimensionless"/>
<variable initial_value="0.19" name="K4" public_interface="out" units="dimensionless"/>
<variable initial_value="4.88" name="k5" public_interface="out" units="dimensionless"/>
<variable initial_value="1.18" name="K6" public_interface="out" units="dimensionless"/>
<variable initial_value="1.24" name="k7" public_interface="out" units="dimensionless"/>
<variable initial_value="32.24" name="k8" public_interface="out" units="dimensionless"/>
<variable initial_value="29.09" name="K9" public_interface="out" units="dimensionless"/>
<variable initial_value="13.58" name="k10" public_interface="out" units="dimensionless"/>
<variable initial_value="153" name="k11" public_interface="out" units="dimensionless"/>
<variable initial_value="0.16" name="K12" public_interface="out" units="dimensionless"/>
</component>
<connection>
<map_components component_1="environment" component_2="a"/>
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<connection>
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<connection>
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<connection>
<map_components component_1="model_parameters" component_2="a"/>
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<map_variables variable_1="k2" variable_2="k2"/>
<map_variables variable_1="k3" variable_2="k3"/>
<map_variables variable_1="K4" variable_2="K4"/>
<map_variables variable_1="k5" variable_2="k5"/>
<map_variables variable_1="K6" variable_2="K6"/>
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<connection>
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<map_variables variable_1="k7" variable_2="k7"/>
<map_variables variable_1="k8" variable_2="k8"/>
<map_variables variable_1="K9" variable_2="K9"/>
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<connection>
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<map_variables variable_1="k10" variable_2="k10"/>
<map_variables variable_1="k11" variable_2="k11"/>
<map_variables variable_1="K12" variable_2="K12"/>
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<map_components component_1="a" component_2="b"/>
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<map_variables variable_1="b" variable_2="b"/>
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<connection>
<map_components component_1="a" component_2="c"/>
<map_variables variable_1="a" variable_2="a"/>
<map_variables variable_1="c" variable_2="c"/>
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Switching from Simple to Complex Oscillations in Calcium Signaling
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