Location: Guidry 2017 Ca2+ transient duration explains the difference between isotonic and isometric cardiac end-systolic force-length relations @ d283cfc042dc / src / Model_Versions / QuickReleaseProtocol.cellml

Author:
Megan Guidry <mgui210@aucklanduni.ac.nz>
Date:
2017-10-30 12:00:49+13:00
Desc:
Added readme.txt
Permanent Source URI:
https://staging.physiomeproject.org/workspace/4ca/rawfile/d283cfc042dc63c7b583a2703586f1f42faee068/src/Model_Versions/QuickReleaseProtocol.cellml
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<?xml version="1.0" encoding="UTF-8"?>
<model xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#"
	xmlns:cellml="http://www.cellml.org/cellml/1.1#" cmeta:id="riceCalciumTransient"
	name="rice_cai">

	<units name="millisecond">
		<unit units="second" prefix="milli" />
	</units>
	<units name="per_millisecond">
		<unit units="millisecond" exponent="-1" />
	</units>

	<component name="interface">
		<variable name="time" public_interface="in"
			private_interface="out" units="millisecond" />
		<variable name="stepStart" public_interface="in"
			private_interface="out" units="millisecond" />
		<variable name="stepDuration" public_interface="in"
			private_interface="out" units="millisecond" />
		<variable name="lambda1" public_interface="in"
			private_interface="out" units="dimensionless" />
		<variable name="lambda2" public_interface="in"
			private_interface="out" units="dimensionless" />
		<variable name="lambda_dot" public_interface="out"
			private_interface="in" units="per_millisecond" />
	</component>
	
	<connection>
		<map_components component_1="interface" component_2="transient"/>
		<map_variables variable_1="time" variable_2="time"/>
		<map_variables variable_1="stepStart" variable_2="stepStart"/>
		<map_variables variable_1="stepDuration" variable_2="stepDuration"/>
		<map_variables variable_1="lambda1" variable_2="lambda1"/>
		<map_variables variable_1="lambda2" variable_2="lambda2"/>
		<map_variables variable_1="lambda_dot" variable_2="lambda_dot"/>
	</connection>

	<component name="transient">
		<variable name="time" public_interface="in" units="millisecond" />
		<variable name="stepStart" public_interface="in" units="millisecond" />
		<variable name="stepDuration" public_interface="in" units="millisecond" />
		<variable name="lambda1" public_interface="in" units="dimensionless" />
		<variable name="lambda2" public_interface="in" units="dimensionless" />

		<variable name="lambda_dot" public_interface="out" units="per_millisecond" />

		<math xmlns="http://www.w3.org/1998/Math/MathML">
			<apply><eq/>
				<ci>lambda_dot</ci>
				<piecewise>
					<piece>
						<cn cellml:units="per_millisecond">0.0</cn>
						<apply><or/>
							<apply><lt/>
								<ci>time</ci>
								<ci>stepStart</ci>
							</apply>
							<apply><gt/>
								<ci>time</ci>
								<apply><plus/>
									<ci>stepStart</ci>
									<ci>stepDuration</ci>
								</apply>
							</apply>
						</apply>
					</piece>
					<otherwise>
						<apply><divide/>
							<apply><minus/>
								<ci>lambda2</ci>
								<ci>lambda1</ci>
							</apply>
							<ci>stepDuration</ci>
						</apply>
					</otherwise>
				</piecewise>
			</apply>
		</math>
	</component>

	<group>
		<relationship_ref relationship="encapsulation" />
		<component_ref component="interface">
			<component_ref component="transient" />
		</component_ref>
	</group>
</model>