A Thermodynamic Model of the Cardiac Sarcoplasmic/Endoplasmic Ca(2+) (SERCA) Pump, Kenneth Tran, Nicolas P. Smith, Denis S. Loiselle, and Edmund J. Crampin, 2009

https://staging.physiomeproject.org/workspace/5ac en-us A Thermodynamic Model of the Cardiac Sarcoplasmic/Endoplasmic Ca(2+) (SERCA) Pump, Kenneth Tran, Nicolas P. Smith, Denis S. Loiselle, and Edmund J. Crampin, 2009 This CellML model has been unit checked and is known to run in OpenCOR. This particular version of the CellML model describes the three-state cooperative SERCA model and recreates figure 13. In order to recreate this figure we have had to add an additional equation to the model to define the rate of change in Casr. Please also note there are typographical errors in the original paper and [H+] should be raised to the power of n (n=2) for T_Hi and T_Hsr. Also in figure 12 the concentrations of ADP should be 8uM and 20uM rather than 20uM and 40uM. This model has been curated and annoted. Added omex file https://staging.physiomeproject.org/workspace/5ac/@@file/6e22649493f77bc7a8f3522e1323b6f4e355b4a4 Added omex file AnandR 2019-09-10 curated model together with separate annotations https://staging.physiomeproject.org/workspace/5ac/@@file/b4f2526b50027619112e06149f9afa217fd37329 curated model together with separate annotations AnandR 2019-09-09 Initial commit https://staging.physiomeproject.org/workspace/5ac/@@file/aaa069cc6393fff76cb671f52f8dd398560e56c3 Initial commit AnandR 2019-09-09