- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2022-03-31 10:48:40+13:00
- Desc:
- Add open channel IV of HH models; Add simulation and plot python scripts
- Permanent Source URI:
- https://staging.physiomeproject.org/workspace/64f/rawfile/ab2962b8796666ad9938a2577611c954f006b5fd/doc/voltage_clamp_experiment.rst
Voltage clamp experiment
----------------------------------------
In the `voltage clamp experiment <../experiments/voltage_clamp_experiment.cellml>`_, the `membrane current model <../components/clamped_current.cellml/view>`_ is configured and parameterised to simulate the behaviour during a `voltage clamp <../experiments/voltage_clamp_protocol.cellml>`_.
You can change the parameters of voltage clamp, such as start/end time and amplitude in the component ``voltage_clamp_protocol_params``.
You can also modify the parameters of temperature :math:`T` and boundary condition of the potential :math:`V_b`, in the component ``parameters`` and ``boundary_conditions`` respectively.
The simulation experiment can be obtained by loading the `corresponding SED-ML document <../sed-ml/voltage_clamp_experiment.sedml>`__ into OpenCOR and executing the simulation.
Membrane currents during a voltage clamp
-----------------------------------------
Figure [#]_ shows the membrane current during a voltage clamp.
.. [#]
.. figure:: ../sed-ml/originalFig11.png
:width: 85%
:align: center
:alt: originalFig11
Membrane current during voltage clamp at 4 :math:`^{\circ} C`
