https://staging.physiomeproject.org/workspace/692 en-us Model of Human Jejunal Smooth Muscle Cell Electrophysiology This workspace encodes the model of human Jejunal smooth muscle cell electrophysiology (Poh et al 2012) Change the figures size to fit the Physiome paper; https://staging.physiomeproject.org/workspace/692/@@file/b98a10f69ee76a70243efdb648c598db5a866a2c Change the figures size to fit the Physiome paper; Adjust the solver setting to remove the notch in Fig6. Minor editting in README. WeiweiAi 2021-07-06 Set interpolate solution to be False, which gives more accurate results for I_Na at around -65mV (i.e., eliminate the notch in Fig6) https://staging.physiomeproject.org/workspace/692/@@file/2a5e59efe1005435ff0fabf7eb400f2929bbb8f8 Set interpolate solution to be False, which gives more accurate results for I_Na at around -65mV (i.e., eliminate the notch in Fig6) WeiweiAi 2021-06-28 Correct the figure numbers in the doc and typos; https://staging.physiomeproject.org/workspace/692/@@file/209ecb42181f3204db0c1119bff2279b6a9b50e0 Correct the figure numbers in the doc and typos; Change the default temerature back to 310K for Periodic_stimulation. WeiweiAi 2021-06-21 Add comments for paramater difference from difference sources in default_values.cellml https://staging.physiomeproject.org/workspace/692/@@file/83d7d73639ae18c0fea6c0befe2b40552ab06de6 Add comments for paramater difference from difference sources in default_values.cellml Add T and Cao in the patch experiment to simulate fig 11; Add T in the periodic stimulation experiment; Add fig 10 and 11; Rerun the simulation and update the documentation. WeiweiAi 2021-06-21 Update figure titles and documentation; https://staging.physiomeproject.org/workspace/692/@@file/4de8d2594e8e71c62b4f118f49fde8a277df70d7 Update figure titles and documentation; WeiweiAi 2021-06-09 Add Fig 9 and 13. https://staging.physiomeproject.org/workspace/692/@@file/ed62e0421bdb1b975f4da82982d0d2f5044e0755 Add Fig 9 and 13. WeiweiAi 2021-06-09 Add SA experiment and more documentation, figures https://staging.physiomeproject.org/workspace/692/@@file/73deb9635bb1baf4b6f83f83e7f7d813a1d6e00f Add SA experiment and more documentation, figures WeiweiAi 2021-06-09 Add readme https://staging.physiomeproject.org/workspace/692/@@file/cfd3c54de6779161377a30232d60e0d563aac741 Add readme WeiweiAi 2021-06-08 output norm to confirm the values https://staging.physiomeproject.org/workspace/692/@@file/15a7f6df29ec652518f83b5d8c22478cc74f7b6b output norm to confirm the values WeiweiAi 2021-06-08 Modify tau_dCaT to 1.9508 and the parameter in phi_s (0.05956) to 0.005956 (Eq S-24) based on the C code; https://staging.physiomeproject.org/workspace/692/@@file/ad6aa57de38320e52058da97f9d140a57288d95e Modify tau_dCaT to 1.9508 and the parameter in phi_s (0.05956) to 0.005956 (Eq S-24) based on the C code; Add ICaL_channel_states_off and ICaL_off for Clamped_current_Xi to switch off the Cai dependency. WeiweiAi 2021-06-08 Fixed the path errors /components..; https://staging.physiomeproject.org/workspace/692/@@file/1194b15aca0ab0c5887f2d3e2f6193792e688f04 Fixed the path errors /components..; Modify the parameters to comply with the ones that the author provided C code (https://computationalbiolab.github.io/jejunal_smc_model/) used. WeiweiAi 2021-06-08 Add python scripts for simulation https://staging.physiomeproject.org/workspace/692/@@file/d8f9669b7d1ee26109713d1ead38c648f264ef02 Add python scripts for simulation WeiweiAi 2021-06-03 Import Unit nM4 https://staging.physiomeproject.org/workspace/692/@@file/68ff9dc17ec43b6ca2fe7d9e3c35bbe4d31e43ee Import Unit nM4 WeiweiAi 2021-06-03 Fixed the different reference T0 for ICaL and ICaT; Add python scripts for Fig8 simulation and plot. There is a big error in Cai which needs further investigation https://staging.physiomeproject.org/workspace/692/@@file/0a4d4ceb54b199b7a72cb8079cc47ad66f9f2bfc Fixed the different reference T0 for ICaL and ICaT; Add python scripts for Fig8 simulation and plot. There is a big error in Cai which needs further investigation WeiweiAi 2021-06-03 Move experiment parameters to *experiment.cellml; https://staging.physiomeproject.org/workspace/692/@@file/35ab51ea8b04aabb9a11ea40ea7411dd07a3433d Move experiment parameters to *experiment.cellml; Add intracellular concentrations to the outputs; Add clamp protocol and experiments; Add the figures in the paper and digitalized data (not complete yet). WeiweiAi 2021-06-02 Add E_Nernst to instantiate Nernst potential for Ca, Na and K and modify relevant models to accommodate the change. https://staging.physiomeproject.org/workspace/692/@@file/d5a44a9d949275dfd1b2e46aeaa827571356cd68 Add E_Nernst to instantiate Nernst potential for Ca, Na and K and modify relevant models to accommodate the change. Add experiment of Periodic_stimulation, which can run. WeiweiAi 2021-06-02 Add more components; Membrane_potential passed the validation with "[Warning] [128:38] Units validation results may be incorrect because the exponent is not a constant." https://staging.physiomeproject.org/workspace/692/@@file/16b60039d43648fceaf9bcbb117f9e27f45e61ac Add more components; Membrane_potential passed the validation with "[Warning] [128:38] Units validation results may be incorrect because the exponent is not a constant." WeiweiAi 2021-06-01 Basic components https://staging.physiomeproject.org/workspace/692/@@file/26dfaf9f7aa1a8893de4b999a3ef076e883ec472 Basic components WeiweiAi 2021-05-31