https://staging.physiomeproject.org/workspace/6f8 en-us Based on Saucerman 2003 model of Gs activation. With RG and LRG as substrates that can cause activation of Gs protein https://staging.physiomeproject.org/workspace/6f8/@@file/4e0bd2426bf04271c75a967dc3c8662b44877fa8 Updating Knames Shelley Fong 2021-11-26 https://staging.physiomeproject.org/workspace/6f8/@@file/3d22412481a02e40d5b58be7146a274779b19ca8 Using sympy for rational nullspace Shelley Fong 2021-11-17 https://staging.physiomeproject.org/workspace/6f8/@@file/8d20a88d38dc5e4f4323ffe434401ad27c54b96c Finding rational nullspace Shelley Fong 2021-11-16 https://staging.physiomeproject.org/workspace/6f8/@@file/83747367ccf20efba25ad4862d0f24a2101f7007 Adding GDP phosphorylation rxn Shelley Fong 2021-11-11 https://staging.physiomeproject.org/workspace/6f8/@@file/7414c15b7bd1d03b821cf9812b83ab9f1f235b85 Automating more Shelley Fong 2021-11-02 https://staging.physiomeproject.org/workspace/6f8/@@file/7498a82d5917abfe4676dadc2c06a677c86a8501 Renaming kinetic_parameters.py Shelley Fong 2021-10-28 https://staging.physiomeproject.org/workspace/6f8/@@file/604051600360f034ab131bab7ad073d6344d701a Renaming rxnID Shelley Fong 2021-10-27 https://staging.physiomeproject.org/workspace/6f8/@@file/4d2215685cfb382dfb3fc2f0044ec0dd1b759301 Removing legacy excel file Shelley Fong 2021-10-27 https://staging.physiomeproject.org/workspace/6f8/@@file/e82436d25e4e943d176fd736f0622316e8f88e07 Adding intermediate compound in GEF reaction scheme Shelley Fong 2021-10-26 https://staging.physiomeproject.org/workspace/6f8/@@file/b0896a70c65cf2ac9643cb95a4760c35892db411 Updating equations to reflect GEF action and remove wrong phosphate bindings Shelley Fong 2021-10-22 https://staging.physiomeproject.org/workspace/6f8/@@file/c575f3746f54f64882b827640a0758690b11d2af Removing MATLAB files Shelley Fong 2021-10-20 https://staging.physiomeproject.org/workspace/6f8/@@file/98afa26f980765279e785c68059e1b9d2a53655a Adding remaining python files or modifications Shelley Fong 2021-10-20 https://staging.physiomeproject.org/workspace/6f8/@@file/8e8cd7ab909820c521d1e4e9055fc00bb7a894bd Rename folder and add new py solver file Shelley Fong 2021-10-20 https://staging.physiomeproject.org/workspace/6f8/@@file/f745663254fa9f0e6725b1be3ade8082965426c8 Adding ODEs for RGP and LRGP Shelley Fong 2021-10-15 https://staging.physiomeproject.org/workspace/6f8/@@file/14d8955cb28095baf5f015b06c1f617e8d8bb343 Updating contraints Shelley Fong 2021-10-14 https://staging.physiomeproject.org/workspace/6f8/@@file/2ecc1f3c1be64e7303ea37525c5fd68397477ee4 Including phosphate binding RG and LRG as a separate reaction. Updating stoichiometry and including 2 new reactions and 2 new chemical species as a result Shelley Fong 2021-10-14 https://staging.physiomeproject.org/workspace/6f8/@@file/6a915bbd5a7141462df1ddef4e588653e830dea7 wapping G for RG and LRG as substrates for act1 and act2 reactions Shelley Fong 2021-10-13 https://staging.physiomeproject.org/workspace/6f8/@@file/e85eb6b2bc0cef35c2251a692337e8fddd861b2a Adding ODE for Pi Shelley Fong 2021-10-12 https://staging.physiomeproject.org/workspace/6f8/@@file/febf8a99ba6beb301c6f0b8434da2c4237885466 Undoing previous change Shelley Fong 2021-10-12 https://staging.physiomeproject.org/workspace/6f8/@@file/f0a2e209c138687400200aa7743453e592f28701 Remove R and LR terms from mu affinities for v_act1/2 Shelley Fong 2021-10-12 https://staging.physiomeproject.org/workspace/6f8/@@file/bef3a8209550da14378fda1d106c758e6bd5befe Adding conservation of chemostat mass check in environment. Fixing ICs to have negligible enzyme complexes Shelley Fong 2021-10-11 https://staging.physiomeproject.org/workspace/6f8/@@file/2120404c442b87f9d38324140dcc031e80ad2736 adding mu_Pi to reaction velocities Shelley Fong 2021-10-04 https://staging.physiomeproject.org/workspace/6f8/@@file/f66afc283e9ba82310df6598e2f799ef40cbc8e9 Adding phosphate group Shelley Fong 2021-10-04 https://staging.physiomeproject.org/workspace/6f8/@@file/8d970d75d42b7dba2e6ddc41b3ac67d9be360754 Updating reaction equations with new stoichiometry for Act reaction Shelley Fong 2021-10-01 https://staging.physiomeproject.org/workspace/6f8/@@file/a3a885d3814c7115f5cc7522e31ed089571a7f01 Separate G from R in stoichiometry Shelley Fong 2021-10-01 https://staging.physiomeproject.org/workspace/6f8/@@file/60c4ba5654c30ea13bd29b7f5748291891e83a2c Updating closed loops in G protein metabolism Shelley Fong 2021-09-28 https://staging.physiomeproject.org/workspace/6f8/@@file/ff50c0fa690b0d938e0b2301c2e3e32f25a66941 Using common PMR repo for units_and_constants Shelley Fong 2021-09-17 https://staging.physiomeproject.org/workspace/6f8/@@file/10af520e90243fcb47542fbc6d0262a47e999351 renaming parameters and updating matlab file Shelley Fong 2021-09-17 https://staging.physiomeproject.org/workspace/6f8/@@file/981e19a814d8be6238bc44ff78b7a5a8b84b159e Changing names of parameters Shelley Fong 2021-09-16 https://staging.physiomeproject.org/workspace/6f8/@@file/a1c913d801854e35d55a36c83a44b5e59f1512e2 adding Pub: out Shelley Fong 2021-09-07 https://staging.physiomeproject.org/workspace/6f8/@@file/9aca7ec32f3bff2f87059165dfa03a8faa49b554 Fixing pub: out Shelley Fong 2021-09-07 https://staging.physiomeproject.org/workspace/6f8/@@file/a05bf8cc1363ada49a4336ac45b9eb004cbd53e1 Fixing stoich matrix and exporting all variables form module to global environment in cellml Shelley Fong 2021-09-06 https://staging.physiomeproject.org/workspace/6f8/@@file/558f121d27348301fbd619c79c4817c16ace9629 Bug fixes Shelley Fong 2021-09-06 https://staging.physiomeproject.org/workspace/6f8/@@file/cf2ff7c2fc383938e5a62dd05d70cdbca90bed11 Fixing ODEs Shelley Fong 2021-09-02 https://staging.physiomeproject.org/workspace/6f8/@@file/81ba8159b34c8acdf9f5357bd77233ef773502f1 Fixing comment on units for Gs module Shelley Fong 2021-09-02 https://staging.physiomeproject.org/workspace/6f8/@@file/71700e2c4992bbd35d44e09b87d2d911d64ffe91 Fixing kinetic units Shelley Fong 2021-09-02 https://staging.physiomeproject.org/workspace/6f8/@@file/49f98f0dd2d4bea43ed5cdc9614e22ef2a0a42c8 Renaming 'GPCR' to 'GsProtein' as the former name is wrong Shelley Fong 2021-08-31 https://staging.physiomeproject.org/workspace/6f8/@@file/323b8195f980ce2bb1432dc0532a7a9d1245a359 Tidying up files Shelley Fong 2021-08-30 https://staging.physiomeproject.org/workspace/6f8/@@file/a49a5c3db55972ea84a81b002f53b21f4739e28e Adding volume arguments and changing dimensions of input kinetic parameters to uM (source literature) Shelley Fong 2021-08-25 https://staging.physiomeproject.org/workspace/6f8/@@file/411ca84a409a6547ea7c04403233d45e96e0f152 Rename file; use constants_BG.cellml import Shelley Fong 2021-07-26 https://staging.physiomeproject.org/workspace/6f8/@@file/5c1390117dceaede46debd5f51af280f5bf5887a Consolidating imports of units and constants Shelley Fong 2021-07-26 https://staging.physiomeproject.org/workspace/6f8/@@file/579c3eafb150c243ed14e5abd3dde53932a1fee4 Removing unnecessary file Shelley Fong 2021-07-26 https://staging.physiomeproject.org/workspace/6f8/@@file/388451396a719f4944f3bdbc3b121ce2855589df Adding MATLAB script to call function to find kinetic parameters. One for each module. Shelley Fong 2021-07-26 https://staging.physiomeproject.org/workspace/6f8/@@file/9b5f31178365f22c5a7e7c2f23cfbc64e674048f Initial commit Shelley Fong 2021-07-22 https://staging.physiomeproject.org/workspace/6f8/@@file/209c5d96543a21996fdc1dd0038da700a2bbdcd6 Making various adjustments for thermodynamic consistency which are not part of original kinetic model Shelley Fong 2021-07-15 https://staging.physiomeproject.org/workspace/6f8/@@file/810eac117f2e040ef6f0932bcbc09346888139ac Adding scheme for making LRG from L,R,G Shelley Fong 2021-07-08 https://staging.physiomeproject.org/workspace/6f8/@@file/3a1148e2a1e6d81f3921764f22b31f3a669ac390 Comparing BG version against kinetic Saucerman03 model Shelley Fong 2021-07-07 https://staging.physiomeproject.org/workspace/6f8/@@file/7007271f759c14360b3ece7c36f74605289f606e Initial commit Shelley Fong 2021-07-05