- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2021-10-07 16:58:17+13:00
- Desc:
- expose the steady states and time constants of gating variables for validation
- Permanent Source URI:
- https://staging.physiomeproject.org/workspace/701/rawfile/3e34bdeaadb951fff681d9fc6104b9b166df3e12/Simulation/src/Figs_sim.py
# To reproduce the data needed for clamping experiments in associated original paper,
import clampExp
import imp
imp.reload(clampExp)
'''
simFign='FigA1F'
V_clamp=[-60, 120, 120, -50, 50, 10]
paraKeys=['Clamp_parameters/Cai']
paras=[9.43e-5]
outKeys=['outputs/I_CaL']
clampExp.clampExp(simFign, V_clamp,paraKeys,paras,outKeys)
simFign='FigA2F'
V_clamp=[-80, 100, 100, -70, 50, 10]
paraKeys=['Clamp_parameters/Cai']
paras=[9.43e-5]
outKeys=['outputs/I_CaT']
clampExp.clampExp(simFign, V_clamp,paraKeys,paras,outKeys)
simFign='FigA3F'
V_clamp=[-90, 50, 50, -50, 50, 10]
paraKeys=['Clamp_parameters/Nai']
paras=[4]
outKeys=['outputs/I_Na']
clampExp.clampExp(simFign, V_clamp,paraKeys,paras,outKeys)
simFign='FigA4F'
V_clamp=[-80, 8000, 8000, -60, 60, 10]
paraKeys=['Clamp_parameters/Ki']
paras=[140]
outKeys=['outputs/I_K1']
clampExp.clampExp(simFign, V_clamp,paraKeys,paras,outKeys)
'''
simFign='FigA5F'
V_clamp=[-80, 8000, 8000, -60, 60, 10]
paraKeys=['Clamp_parameters/Ki']
paras=[140]
outKeys=['outputs/I_K2']
clampExp.clampExp(simFign, V_clamp,paraKeys,paras,outKeys)
simFign='FigA6F'
V_clamp=[-80, 150, 150, -80, 60, 10]
paraKeys=['Clamp_parameters/Ki']
paras=[140]
outKeys=['outputs/I_KA']
clampExp.clampExp(simFign, V_clamp,paraKeys,paras,outKeys)
simFign='FigA7F'
V_clamp=[-10, 3000, 3000, -20, 130, 10]
paraKeys=['Clamp_parameters/Nai','Clamp_parameters/Ki']
paras=[4,140]
outKeys=['outputs/I_h']
clampExp.clampExp(simFign, V_clamp,paraKeys,paras,outKeys)
simFign='FigA8F'
V_clamp=[0, 100, 100, -60, 40, 10]
paraKeys=['Clamp_parameters/Cai']
paras=[9.43e-5]
outKeys=['outputs/I_Cl']
clampExp.clampExp(simFign, V_clamp,paraKeys,paras,outKeys)
