Location: Single PASMC model (Gosak et al 2014) @ d3481301a126 / Components / Cai.txt

Author:

WeiweiAi <wai484@aucklanduni.ac.nz>

Date:

2022-04-20 10:25:24+12:00

Desc:

Pass the inputs to the children models

Permanent Source URI:

https://staging.physiomeproject.org/workspace/83f/rawfile/d3481301a126fe74f4212e78066010c35d3c91f8/Components/Cai.txt

def model Cai as
    def import using "../cellLib/Components/units.cellml" for
        unit mV using unit mV;
        unit per_s using unit per_s;
        unit uM using unit uM;
        unit uM_per_s using unit uM_per_s;
        unit uM_per_s_mV using unit uM_per_s_mV;
    enddef;

    def import using "JVOCCi.cellml" for
        comp JVOCCi using comp JVOCCi;
    enddef;

    def import using "JNCXi.cellml" for
        comp JNCXi using comp JNCXi;
    enddef;

    def import using "JSERCAi.cellml" for
        comp JSERCAi using comp JSERCAi;
    enddef;

    def import using "JCICRi.cellml" for
        comp JCICRi using comp JCICRi;
    enddef;

    def import using "JPMCAi.cellml" for
        comp JPMCAi using comp JPMCAi;
    enddef;

    def import using "Jleaki.cellml" for
        comp Jleaki using comp Jleaki;
    enddef;

    def comp Cai as
        var L: per_s {pub: in, priv: out};
        var D: per_s {pub: in, priv: out};
        var v_d: mV {pub: in, priv: out};
        var R_d: mV {pub: in, priv: out};
        var C: uM_per_s {pub: in, priv: out};
        var s_c: uM {pub: in, priv: out};
        var c_c: uM {pub: in, priv: out};
        var B: uM_per_s {pub: in, priv: out};
        var c_b: uM {pub: in, priv: out};
        var G_NCX: uM_per_s_mV {pub: in, priv: out};
        var v_NCX: mV {pub: in, priv: out};
        var c_NCX: uM {pub: in, priv: out};
        var G_Ca: uM_per_s_mV {pub: in, priv: out};
        var v_Ca1: mV {pub: in, priv: out};
        var v_Ca2: mV {pub: in, priv: out};
        var R_Ca: mV {pub: in, priv: out};
        var J_VOCCi: uM_per_s {pub: out, priv: in};
        var J_NCXi: uM_per_s {pub: out, priv: in};
        var J_SERCAi: uM_per_s {pub: out, priv: in};
        var J_CICRi: uM_per_s {pub: out, priv: in};
        var J_PMCAi: uM_per_s {pub: out, priv: in};
        var J_leaki: uM_per_s {pub: out, priv: in};
        var t: second {pub: in};
        var ci_init: uM {pub: in};
        var c_i: uM {init: ci_init, pub: out, priv: out};

        ode(c_i,t)=J_VOCCi-J_NCXi-J_SERCAi+J_CICRi-J_PMCAi+J_leaki;

    enddef;

    def group as encapsulation for
        comp Cai incl
            comp JVOCCi;
            comp JNCXi;
            comp JSERCAi;
            comp JCICRi;
            comp JPMCAi;
            comp Jleaki;
        endcomp;
    enddef;

    def map between Cai and JVOCCi for
        vars G_Ca and G_Ca;
        vars J_VOCCi and J_VOCCi;
        vars R_Ca and R_Ca;
        vars v_Ca1 and v_Ca1;
        vars v_Ca2 and v_Ca2;
    enddef;

    def map between Cai and JNCXi for
        vars G_NCX and G_NCX;
        vars J_NCXi and J_NCXi;
        vars c_NCX and c_NCX;
        vars c_i and c_i;
        vars v_NCX and v_NCX;
    enddef;

    def map between Cai and JSERCAi for
        vars B and B;
        vars J_SERCAi and J_SERCAi;
        vars c_b and c_b;
        vars c_i and c_i;
    enddef;

    def map between Cai and JCICRi for
        vars C and C;
        vars J_CICRi and J_CICRi;
        vars c_c and c_c;
        vars c_i and c_i;
        vars s_c and s_c;
    enddef;

    def map between Cai and JPMCAi for
        vars D and D;
        vars J_PMCAi and J_PMCAi;
        vars R_d and R_d;
        vars c_i and c_i;
        vars v_d and v_d;
    enddef;

    def map between Cai and Jleaki for
        vars J_leaki and J_leaki;
        vars L and L;
    enddef;

enddef;