Location: Intracellular pH regulation @ 2325464752c3 / models / CellMLV2 / Boron_NH3_BG_V3.cellml

Author:

WeiweiAi <wai484@aucklanduni.ac.nz>

Date:

2024-02-09 13:41:13+13:00

Desc:

Add new model *fit_1.cellml; Refit CO2_BG_V3; Boron_acid_BG_V3_Hi using Boron version of ODE for q_H_i;

Permanent Source URI:

https://staging.physiomeproject.org/workspace/b61/rawfile/2325464752c3a2c9916a3a792f1e1ffc3ccf73b2/models/CellMLV2/Boron_NH3_BG_V3.cellml

<?xml version="1.0" encoding="UTF-8"?>
<model xmlns="http://www.cellml.org/cellml/2.0#" name="BG51">
  <units name="dim">
    <unit units="dimensionless"/>
  </units>
  <units name="per_s">
    <unit exponent="-1" units="second"/>
  </units>
  <units name="mol_per_s">
    <unit units="mole"/>
    <unit exponent="-1" units="second"/>
  </units>
  <units name="per_mol">
    <unit exponent="-1" units="mole"/>
  </units>
  <units name="per_mol2">
    <unit exponent="-2" units="mole"/>
  </units>
  <units name="C_per_mol">
    <unit units="coulomb"/>
    <unit exponent="-1" units="mole"/>
  </units>
  <units name="J_per_mol">
    <unit units="joule"/>
    <unit exponent="-1" units="mole"/>
  </units>
  <units name="J_per_C">
    <unit units="joule"/>
    <unit exponent="-1" units="coulomb"/>
  </units>
  <component name="main">
    <variable name="q_NH3_i" units="mole" initial_value="0"/>
    <variable name="q_NH3_o" units="mole" initial_value="0.14"/>
    <variable name="K_NH3_o" units="per_mol" initial_value="1e3"/>
    <variable name="K_NH3_i" units="per_mol" initial_value="1e3"/>
    <variable name="Q_NH3_o" units="dim"/>
    <variable name="Q_NH3_i" units="dim"/>
    <variable name="t" units="second"/>
    <variable name="v_NH3_m" units="mol_per_s"/>
    <variable name="v_NH3_max" units="mol_per_s" initial_value="9.600e-04"/>
    <variable name="gamma_NH3" units="dim" initial_value="1.000e+09"/>
    <math xmlns="http://www.w3.org/1998/Math/MathML" xmlns:cellml="http://www.cellml.org/cellml/2.0#">
      <apply>
        <eq/>
        <ci>Q_NH3_o</ci>
        <apply>
          <times/>
          <ci>K_NH3_o</ci>
          <ci>q_NH3_o</ci>
        </apply>
      </apply>
      <apply>
        <eq/>
        <ci>Q_NH3_i</ci>
        <apply>
          <times/>
          <ci>K_NH3_i</ci>
          <ci>q_NH3_i</ci>
        </apply>
      </apply>
      <apply>
        <eq/>
        <apply>
          <diff/>
          <bvar>
            <ci>t</ci>
          </bvar>
          <ci>q_NH3_i</ci>
        </apply>
        <cn cellml:units="mol_per_s">0.01</cn>
      </apply>
    </math>
    <math xmlns="http://www.w3.org/1998/Math/MathML" xmlns:cellml="http://www.cellml.org/cellml/2.0#">
      <apply>
        <eq/>
        <ci>v_NH3_m</ci>
        <apply>
          <divide/>
          <apply>
            <times/>
            <ci>v_NH3_max</ci>
            <apply>
              <plus/>
              <cn cellml:units="dim">1</cn>
              <ci>gamma_NH3</ci>
            </apply>
            <apply>
              <minus/>
              <ci>Q_NH3_o</ci>
              <ci>Q_NH3_i</ci>
            </apply>
          </apply>
          <apply>
            <plus/>
            <apply>
              <times/>
              <cn cellml:units="dim">2</cn>
              <ci>gamma_NH3</ci>
            </apply>
            <ci>Q_NH3_o</ci>
            <ci>Q_NH3_i</ci>
            <apply>
              <times/>
              <cn cellml:units="dim">2</cn>
              <ci>Q_NH3_o</ci>
              <ci>Q_NH3_i</ci>
            </apply>
          </apply>
        </apply>
      </apply>
    </math>
  </component>
</model>