- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2024-02-06 18:13:57+13:00
- Desc:
- Update base models
- Permanent Source URI:
- https://staging.physiomeproject.org/workspace/b61/rawfile/bb37bbe8fcce0608f2df5efccfa1e6f45d220305/models/modules/Boron_HCO3_BG.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="BG51" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#">
<!-- Intracellular pH regulation-->
<units name="dim">
<unit units="dimensionless"/>
</units>
<units name="per_s">
<unit exponent="-1" units="second"/>
</units>
<units name="mol_per_s">
<unit units="mole"/>
<unit exponent="-1" units="second"/>
</units>
<units name="per_mol">
<unit exponent="-1" units="mole"/>
</units>
<units name="per_mol2">
<unit exponent="-2" units="mole"/>
</units>
<units name="C_per_mol">
<unit units="coulomb"/>
<unit exponent="-1" units="mole"/>
</units>
<units name="J_per_mol">
<unit units="joule"/>
<unit exponent="-1" units="mole"/>
</units>
<units name="J_per_C">
<unit units="joule"/>
<unit exponent="-1" units="coulomb"/>
</units>
<component name="main">
<variable initial_value="9.64853321e4" name="F" units="C_per_mol"/>
<variable initial_value="2462.1911" name="RT" units="J_per_mol"/>
<variable initial_value="-0.057" name="u_e_m" units="J_per_C"/>
<variable name="epsilon" units="dim"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>epsilon</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<ci>F</ci>
<ci>u_e_m</ci>
</apply>
<ci>RT</ci>
</apply>
</apply>
</apply>
</math>
<!-- state variables-->
<variable initial_value="0" name="q_HCO3_i" units="mole"/>
<variable initial_value="60" name="q_HCO3_o" units="mole"/>
<variable name="t" units="second"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_HCO3_i</ci>
</apply>
<cn cellml:units="mol_per_s">0.5</cn>
</apply>
</math>
<!-- substrate solubilities-->
<variable initial_value="1e-5" name="K_HCO3_s" units="per_mol"/>
<variable name="v_HCO3_m" public_interface="out" units="mol_per_s"/>
<variable initial_value="10.01" name="kappa_HCO3_m" units="mol_per_s"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>v_HCO3_m</ci>
<apply>
<times/>
<ci>kappa_HCO3_m</ci>
<ci>K_HCO3_s</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>q_HCO3_o</ci>
<ci>epsilon</ci>
</apply>
<ci>q_HCO3_i</ci>
</apply>
</apply>
</apply>
</math>
<!-- // Nernst relations (to check that molar qtys satisfy equilibrium conditions)-->
<!-- var u_HCO3_Nernst: J_per_C;
var u_H_Nernst: J_per_C;
var u_NH4_Nernst: J_per_C;-->
<!-- u_HCO3_Nernst = RT/F*ln(q_HCO3_o/q_HCO3_i);
u_H_Nernst = RT/F*ln(q_H_o/q_H_i);
u_NH4_Nernst = RT/F*ln(q_NH4_o/q_NH4_i);-->
</component>
</model>
