Introduction
=============
This workspace illustrates how to connect multiscale models using the bond graph formalism.

The main CellML_ files in folder <models> are:

- cardiovascular.cellml encodes a circulation system simplified from `Gee, Michelle M., et al.(2023)`_. The model follows the bond graph formalism.
- neural_control.cellml encodes the neural control model described in `Gee, Michelle M., et al.(2023)`_.
- tentusscher_noble_noble_panfilov_2004_m.cellml encodes the M cell action potential model described in `Ten Tusscher et al. 2004`_
- Gee_whiz.cellml connects the M cell action potential model to the circulation model via the tension model described in `HMT 1998`_
- the folder <CellMLV2> includes the flattened Gee_whiz model using CellML version 2 Gee_whiz_flat.cellml and its SED-ML_ file. 

.. _CellML: https://www.cellml.org/
.. _OpenCOR: https://opencor.ws/
.. _SED-ML: https://sed-ml.org

.. _`Gee, Michelle M., et al.(2023)`: https://doi.org/10.1002/aic.18033
.. _`Ten Tusscher et al. 2004`: https://doi.org/10.1152/ajpheart.00794.2003
.. _`HMT 1998`: https://doi.org/10.1016/s0079-6107(98)00013-3