https://staging.physiomeproject.org/workspace/c65 en-us This model extension offers the possibility to simulate the sinoatrial node cell models of Severi et al. (2012) and Fabbri et al. (2017) with the AC-cAMP-PKA signalling cascade based on the work of Behar et al. (2016) and fixes the [ISO]-induced conductance changes in ICaL as described by Linder et al. (2025), DOI: https://doi.org/10.1113/JP287557. https://staging.physiomeproject.org/workspace/c65/@@file/c858eebb4bdbe4ba7b52c73fcf924ad4c720376a feat: changed to 1 html file ml0401 2025-05-05 https://staging.physiomeproject.org/workspace/c65/@@file/95db8d627beef8d27783ae6fa2381a2fb47b123a feat: added exposure html file ml0401 2025-05-05 https://staging.physiomeproject.org/workspace/c65/@@file/20f26c1f396c306ce93a90b3c9e935a08027d9e5 feat: added exposure images ml0401 2025-05-05 https://staging.physiomeproject.org/workspace/c65/@@file/84847563574dcba2896b97382b6840d472fc67ee feat: added new IKACh formulation + refactoring ml0401 2025-04-11 https://staging.physiomeproject.org/workspace/c65/@@file/d2533845d2ef626433620c5ebcd275c61b17e6f7 chore: minor adjustment ml0401 2025-04-11 https://staging.physiomeproject.org/workspace/c65/@@file/265beb9cc499c1c716d5a8940ec7ba2a8eb2cf8c refactor: IKACh gating ml0401 2025-04-11 https://staging.physiomeproject.org/workspace/c65/@@file/3ccce0f46301c5afc3b9848ff89dac715819d0be feat: added new IKACh formulation + refactoring ml0401 2025-04-11 https://staging.physiomeproject.org/workspace/c65/@@file/d5080962e5f78df117a2861a2c74f5cd27026d3f feat: adjusted extended Severi and added extended Fabbri model ml0401 2025-02-05 https://staging.physiomeproject.org/workspace/c65/@@file/8db0b42d41d9aa056350ad8ddf821cc2d9ab354f fix: missing mapping between interface vars ml0401 2025-01-28 https://staging.physiomeproject.org/workspace/c65/@@file/067db559ae51b0f8a4e895a29897e769e53d2a06 feat: added AC-cAMP-PKA signalling cascade and influence on targets ml0401 2025-01-28 https://staging.physiomeproject.org/workspace/c65/@@file/c99beffdc5bdbb487bc220d9f854c910fbb6cd35 feat: initial Severi model ml0401 2025-01-28