- Author:
- Shelley Fong <sfon036@UoA.auckland.ac.nz>
- Date:
- 2025-02-10 12:06:41+13:00
- Desc:
- Init
- Permanent Source URI:
- https://staging.physiomeproject.org/workspace/c6c/rawfile/b8595255245cc90012ce92f494dc953eb6093064/README.rst
The SLC family: SGLT1 (SLC5A1)
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This example is designed to show electrogenic cotransport through the SGLT1 (SLC5A1) transporter, transporting one glucose molecule intro the *small intestine* with two sodium ions. The bond-graph model is illustrated in the figure below, with the CellML model defining the *reduced? model of steady-state flux assuming rapid binding and unbinding.*
.. figure:: SGLT_simplification.png
:width: 95%
:align: center
:alt: Bond graph of the model
The bond graph representation of transport of glucose amd sodium through the SGLT1 transporter.
The **Views Available** menu to the right provides various options to explore this model here in the Physiome Model Repository.
Of particular interest is the *Launch with OpenCOR* menu item, which will load the simulation experiment shown below directly into the `OpenCOR`_ desktop application.
.. figure:: sedml_results.png
:width: 95%
:align: center
:alt: OpenCOR showing simulation experiment.
Showing the result of launching the simulation experiment from this exposure in OpenCOR and executing the simulation.
.. _CellML: https://www.cellml.org/
.. _OpenCOR: https://opencor.ws/
.. _SED-ML: https://sed-ml.org
