Location: NHE1 - The Physics of Physiology @ e0e025696518 / README.rst

Author:
Shelley Fong <sfon036@UoA.auckland.ac.nz>
Date:
2025-02-18 12:12:05+13:00
Desc:
Init
Permanent Source URI:
https://staging.physiomeproject.org/workspace/c74/rawfile/e0e025696518200f101fae6012ba347ec447065b/README.rst

The SLC family: The SLC family: NHE1 (SLC9A1)
======================================================================================

Sodium hydrogen exchanger

This transporter allows entry of one sodium ion in exchange for the entrusion of one hydrogen ion from the cell. The bond-graph model is illustrated in the figure below, with the CellML model added for simulation purposes.

.. figure::  NHE1_simplification.png
   :width: 95%
   :align: center
   :alt: Schematic and bond graph of the model

   The bond graph representation of the NHE1, showing simplification of the full bond graph into the reduced form.

The **Views Available** menu to the right provides various options to explore this model here in the Physiome Model Repository.
Of particular interest is the *Launch with OpenCOR* menu item, which will load the simulation experiment shown below directly into the `OpenCOR`_ desktop application.

Because this has not been parameterised yet, there are no simulation results to show. The associated CellML file contains all equations needed to execute this model.


.. _CellML: https://www.cellml.org/
.. _OpenCOR: https://opencor.ws/
.. _SED-ML: https://sed-ml.org