Location: EAAT2 - The Physics of Physiology @ 2facb5c2c1f9 / README.rst

Author:
Shelley Fong <sfon036@UoA.auckland.ac.nz>
Date:
2025-02-24 10:50:36+13:00
Desc:
Changing Glt to Glu
Permanent Source URI:
https://staging.physiomeproject.org/workspace/c85/rawfile/2facb5c2c1f9b404a5ee8ed800792399aef289a9/README.rst

The SLC family: EAAT2 (SLC1A2)
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Glutamate transporter

This transporter allows entry of glutamate coupled with 3 sodium and one hydrogen ion, in exchange for one potassium ion expelled from the cell.
The bond-graph model is illustrated in the figure below, with the CellML model added for simulation purposes.

.. figure::  EAAT2_simplification.png
   :width: 95%
   :align: center
   :alt: Schematic and bond graph of the model

   The bond graph representation of the EAAT2, showing simplification of the full bond graph into the reduced form.

Because this has not been parameterised yet, there are no simulation results to show. The associated CellML file contains all equations needed to execute this model.


.. _CellML: https://www.cellml.org/
.. _OpenCOR: https://opencor.ws/
.. _SED-ML: https://sed-ml.org