Location: SERCA - The Physics of Physiology @ 321507426a34 / README.rst

Author:
Shelley Fong <sfon036@UoA.auckland.ac.nz>
Date:
2025-03-03 13:43:02+13:00
Desc:
Adding readme
Permanent Source URI:
https://staging.physiomeproject.org/workspace/c98/rawfile/321507426a34c1dea81f5a4b6ca85757d1250b5a/README.rst

ATPase pumps: Calcium ATPase (SERCA)
======================================================================================

This ATPase pumps out 2 calcium ions from the sarcoplasmic reticulum, and one hydrogen ion enters. For this process, one ATP molecule is hydrolysed. The bond-graph model is illustrated in the figure below, with the CellML model added for simulation purposes.

.. figure::  SERCA_BG_diagram_simplification.png
   :width: 95%
   :align: center
   :alt: Schematic and bond graph of the model

   The bond graph representation of the HKE, showing simplification of the full bond graph into the reduced form.


Because this has not been parameterised yet, there are no simulation results to show. The associated CellML file contains all equations needed to execute this model.


.. _CellML: https://www.cellml.org/
.. _OpenCOR: https://opencor.ws/
.. _SED-ML: https://sed-ml.org