Location: Blood volume control model @ af37def9b5c0 / readme.rst

Author:
David Nickerson <david.nickerson@gmail.com>
Date:
2025-08-14 23:06:51+12:00
Desc:
Adding eating and drinking protocols. Updating the CellML model to include ability to tweak the input boundary conditions; Adding SED-ML for a eating and drinking protocol; Adding the SimulationVuer JSON description for the eating and drinking protocol; Switching to using the SPARC portal mimetype for the SimulationVuer config file.
Permanent Source URI:
https://staging.physiomeproject.org/workspace/c99/rawfile/af37def9b5c012a1ca516b3c82a8dc704c670daa/readme.rst

Blood volume control model
==========================

A simple model of the control of blood volume by sodium. Shown below, the three compartments (GI tract, kidney, and circulation system) are shown with grey backgrounds. The blue-background rectangular boxes indicate the 6-layer FTUs (Functional Tissue Units) that encompass exchange of substances (in this case just water and sodium) between the epithelial compartments and blood. The 0:nodes and 1:nodes provide the link to protein mechanisms in subcellular compartments. The variables shown in red are specified boundary conditions.

.. figure::  BloodVolumeControl.jpg
   :width: 50%
   :align: center
   :alt: Schematic and bond graph of the model

   The figure depicts the components of the renal circulation system.