- Author:
- termi-official <termi-official@users.noreply.github.com>
- Date:
- 2025-05-15 16:01:20+02:00
- Desc:
- Add documentation for submission
- Permanent Source URI:
- https://staging.physiomeproject.org/workspace/d20/rawfile/8465ce0a385cdc40e2f79b001798d600e9f9e4d2/experiments/cell/original_electrical_pacing_experiment.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="electrical_pacing_experiment" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<!-- Not sure how to do this in CellML 2.0-->
<import xlink:href="../../units.cellml">
<units name="u_per_m" units_ref="u_per_m"/>
<units name="ms" units_ref="ms"/>
<units name="per_ms" units_ref="per_ms"/>
<units name="mV" units_ref="mV"/>
<units name="per_mV" units_ref="per_mV"/>
<units name="uS_per_nF" units_ref="uS_per_nF"/>
<units name="nA_per_nF" units_ref="nA_per_nF"/>
<units name="molar" units_ref="molar"/>
<units name="mM" units_ref="mM"/>
<units name="uM" units_ref="uM"/>
<units name="mM4" units_ref="mM4"/>
<units name="mV_per_uM" units_ref="mV_per_uM"/>
<units name="uM_per_ms" units_ref="uM_per_ms"/>
<units name="per_uM_per_ms" units_ref="per_uM_per_ms"/>
<units name="J_per_moleK" units_ref="J_per_moleK"/>
<units name="coulomb_per_mmole" units_ref="coulomb_per_mmole"/>
<units name="cm_per_s" units_ref="cm_per_s"/>
<units name="mA_per_cm2" units_ref="mA_per_cm2"/>
<units name="mmole_per_coulomb_cm" units_ref="mmole_per_coulomb_cm"/>
</import>
<!-- At the time of writing this we have to manually fetch interesting entries here...-->
<component name="outputs">
<variable initial_value="0.0" name="time" public_interface="out" units="ms"/>
<!-- QOIs-->
<variable name="V" public_interface="in" units="mV"/>
<variable name="Ca_dyad" public_interface="in" units="uM"/>
<variable name="Ca_submem" public_interface="in" units="uM"/>
<variable name="Ca_i" public_interface="in" units="uM"/>
<variable name="Ca_NSR" public_interface="in" units="uM"/>
<variable name="Ca_JSR" public_interface="in" units="uM"/>
<!-- Stimulation Settings-->
<variable initial_value="0" name="stim_offset" public_interface="out" units="ms"/>
<variable initial_value="220" name="stim_period" public_interface="out" units="ms"/>
<variable initial_value="3" name="stim_duration" public_interface="out" units="ms"/>
<variable initial_value="-15" name="stim_amplitude" public_interface="out" units="nA_per_nF"/>
</component>
<connection>
<map_components component_1="outputs" component_2="cell_membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="outputs" component_2="Ca"/>
<map_variables variable_1="Ca_dyad" variable_2="Ca_dyad"/>
<map_variables variable_1="Ca_submem" variable_2="Ca_submem"/>
<map_variables variable_1="Ca_i" variable_2="Ca_i"/>
<map_variables variable_1="Ca_NSR" variable_2="Ca_NSR"/>
<map_variables variable_1="Ca_JSR" variable_2="Ca_JSR"/>
</connection>
<import xlink:href="../../models/mahajan_shiferaw_2008.cellml">
<component component_ref="interface" name="cell_model"/>
<component component_ref="cell_membrane" name="cell_membrane"/>
<component component_ref="Ca" name="Ca"/>
</import>
<import xlink:href="../common/periodic_electrical_stim_protocol.cellml">
<component component_ref="stimulus_protocol" name="stimulus_protocol"/>
</import>
<connection>
<map_components component_1="outputs" component_2="stimulus_protocol"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="stim_offset" variable_2="stim_offset"/>
<map_variables variable_1="stim_period" variable_2="stim_period"/>
<map_variables variable_1="stim_duration" variable_2="stim_duration"/>
<map_variables variable_1="stim_amplitude" variable_2="stim_amplitude"/>
</connection>
<connection>
<map_components component_1="outputs" component_2="cell_model"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="stimulus_protocol" component_2="cell_model"/>
<map_variables variable_1="current" variable_2="i_stim"/>
</connection>
</model>
