- Author:
- Shelley Fong <sfon036@UoA.auckland.ac.nz>
- Date:
- 2025-07-18 14:18:20+12:00
- Desc:
- Adding gating
- Permanent Source URI:
- https://staging.physiomeproject.org/workspace/d51/rawfile/71d08ea2728aa74072b1b874541eff4dad159272/parameter_finder/output/TEMP.cellml.txt
def model individual_An01 as
def import using "units_and_constants/units.cellml" for
unit mM using unit mM;
unit fmol using unit fmol;
unit per_fmol using unit per_fmol;
unit J_per_mol using unit J_per_mol;
unit fmol_per_sec using unit fmol_per_sec;
unit C_per_mol using unit C_per_mol;
unit J_per_C using unit J_per_C;
unit microm3 using unit microm3;
unit fF using unit fF;
unit fC using unit fC;
unit fA using unit fA;
unit per_second using unit per_second;
unit millivolt using unit millivolt;
unit per_sec using unit per_sec;
unit J_per_K_per_mol using unit J_per_K_per_mol;
unit fmol_per_L using unit fmol_per_L;
unit fmol_per_L_per_sec using unit fmol_per_L_per_sec;
unit per_sec_per_fmol_per_L using unit per_sec_per_fmol_per_L;
unit uM using unit uM;
unit mM_per_sec using unit mM_per_sec;
unit uM_per_sec using unit uM_per_sec;
unit pL using unit pL;
unit m_to_u using unit m_to_u;
enddef;
def import using "units_and_constants/constants.cellml" for
comp constants using comp constants;
enddef;
def comp environment as
var time: second {pub: out};
// initial values
var q_Cl_i: fmol {init: 1e-888, pub: out};
var q_Cl_o: fmol {init: 1e-888, pub: out};
// From submodule
var v_ReAn01: fmol_per_sec {pub: in};
ode(q_Cl_i, time) = vvv;
ode(q_Cl_o, time) = vvv;
enddef;
def comp An01_parameters as
var kappa_ReAn01: fmol_per_sec {init: 0.00110404, pub: out};
var K_Cl_i: per_fmol {init: 0.000235653, pub: out};
var K_Cl_o: per_fmol {init: 0.00156435, pub: out};
enddef;
def comp An01 as
var time: second {pub: in};
var R: J_per_K_per_mol {pub: in};
var T: kelvin {pub: in};
// parameters
var kappa_ReAn01: fmol_per_sec {pub: in};
var K_Cl_i: per_fmol {pub: in};
var K_Cl_o: per_fmol {pub: in};
// Input from global environment
var q_Cl_i: fmol {pub: in};
var q_Cl_o: fmol {pub: in};
// Constitutive parameters
var mu_Cl_i: J_per_mol;
var mu_Cl_o: J_per_mol;
var v_ReAn01: fmol_per_sec {pub: out};
mu_Cl_i = R*T*ln(K_Cl_i*q_Cl_i);
mu_Cl_o = R*T*ln(K_Cl_o*q_Cl_o);
v_ReAn01 = ppp;
enddef;
def map between environment and An01 for
vars time and time;
vars q_Cl_i and q_Cl_i;
vars q_Cl_o and q_Cl_o;
vars v_ReAn01 and v_ReAn01;
enddef;
def map between An01 and An01_parameters for
vars kappa_ReAn01 and kappa_ReAn01;
vars K_Cl_i and K_Cl_i;
vars K_Cl_o and K_Cl_o;
enddef;
def map between constants and An01 for
vars R and R;
vars T and T;
enddef;
enddef;