Location: GLUT demo for CFDE Summer School in Mechanistic Modeling for PBPK Transport @ 654d22aca937 / simulation.json

Author:

David Nickerson <david.nickerson@gmail.com>

Date:

2025-08-25 22:04:17+12:00

Desc:

Adding flattened model to work on the web simulator and the associated files to build the COMBINE archive.

Permanent Source URI:

https://staging.physiomeproject.org/workspace/d5c/rawfile/654d22aca937fbfb98adc11b672b7b404e26a22f/simulation.json

{
    "input": [
      {
        "defaultValue": 1,
        "id": "g_i",
        "name": "[Gluc]i (mM)",
        "maximumValue": 50,
        "minimumValue": 1
      },
      {
        "defaultValue": 1,
        "id": "kappa_r1",
        "name": "kappa r1 (fmol / s)",
        "maximumValue": 100,
        "minimumValue": 1
      },
      {
        "defaultValue": 150,
        "id": "K_Ai",
        "name": "K_Ai (/fmol)",
        "maximumValue": 500,
        "minimumValue": 150
      }
    ],
    "output": {
      "data": [
        {
          "id": "t",
          "name": "GLUT2_BG/t"
        },
        {
          "id": "v_max",
          "name": "GLUT2_BG/v_max"
        },
        {
          "id": "g_i",
          "name": "GLUT2_BG/g_i"
        },
        {
          "id": "g_o",
          "name": "GLUT2_BG/g_o"
        },
        {
          "id": "v",
          "name": "GLUT2_BG/v"
        }
      ],
      "plots": [
        {
          "yAxisTitle": "v (fmol/s)",
          "yValue": "v",
          "xAxisTitle": "[Gluc]o (mM)",
          "xValue": "g_o"
        }
      ]
    },
    "parameters": [
      {
        "name": "params_BG/kappa_r1",
        "value": "kappa_r1"
      },
      {
        "name": "params_BG/K_Ai",
        "value": "K_Ai"
      },
      {
        "name": "GLUT2_BG/g_i",
        "value": "g_i"
      }
    ]
  }