- Author:
- pmr2.import <nobody@models.cellml.org>
- Date:
- 2008-04-29 15:02:31+12:00
- Desc:
- committing version01 of garny_kohl_hunter_boyett_noble_2003
- Permanent Source URI:
- https://staging.physiomeproject.org/workspace/garny_kohl_hunter_boyett_noble_2003/rawfile/0c361a633ca7460aefe38d7d86c93dab60ebeff5/garny_kohl_hunter_boyett_noble_2003.cellml
<?xml version='1.0' encoding='utf-8'?>
<!--
This CellML file was generated on 11/03/2008 at 16:13:16 using:
COR (0.9.31.897)
Copyright 2002-2008 Dr Alan Garny
http://COR.physiol.ox.ac.uk/ - COR@physiol.ox.ac.uk
CellML 1.0 was used to generate this cellular model
http://www.CellML.org/
--><model xmlns="http://www.cellml.org/cellml/1.0#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqs="http://www.cellml.org/bqs/1.0#" xmlns:cellml="http://www.cellml.org/cellml/1.0#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:ns7="http://www.cellml.org/metadata/simulation/1.0#" cmeta:id="garny_2003" name="garny_2003">
<documentation xmlns="http://cellml.org/tmp-documentation">
<article>
<articleinfo>
<title>Mathematical Model Of Action Potentials In The Periphery Of The Sinoatrial Node, 2000</title>
<author>
<firstname>Penny</firstname>
<surname>Noble</surname>
<affiliation>
<shortaffil>Oxford University</shortaffil>
</affiliation>
</author>
</articleinfo>
<section id="sec_status">
<title>Model Status</title>
<para>
This version of the CellML model was created by Alan Garny of Oxford University, it has been unit checked and the model runs in both COR and PCEnv to reproduce the published results.
</para>
</section>
<sect1 id="sec_structure">
<title>Model Structure</title>
<para>
Cardiac multicellular modeling has traditionally focused on ventricular electromechanics. More recently, models of the atria have started to emerge, and there is much interest in addressing sinoatrial node (SAN) structure and function. The SAN has a heterogeneous structure, with smaller cells being located more centrally and larger ones toward the periphery. In addition, the central SAN cells have a lower maximum diastolic potential (MDP), upstroke velocity (UV), and intrinsic pacemaking rate than the peripheral cells. In the current model, Garny et al. (2003) build further on the SAN model published by Zhang et al. (2000) (also described in CellML) and add a third category of cell called transitional cells. These transitional cell types are obtained by gradation between central and peripheral cell models, using a scaling parameter implemented in the model as a function of cell location relative to the SAN centre. The variable is called dCell and it specifies the relative distance of the cell relative to the centre of the SAN: if dCell=1 it is a peripheral cell model, if dCell=0 it is a central cell, and if dCell has a value between 0 and 1 the model describes a transitional cell.
</para>
<para>
There is a second variable which varies between models; version. If version=0 the CellML model behaves like the Zhang et al. 2000 model. If version=1 the CellML model describes a 0D capable, or suitable for single cell modelling, and if version=2 the CellML model describes a 1D capable, or suitable for multicellular modelling. By default the CellML model is setup to describe a central SAN cell (dCell=0) suitable for single cell modelling (version=1).
</para>
<para>
The complete original paper reference is cited below.
</para>
<para>
<ulink url="http://www.blackwell-synergy.com/doi/abs/10.1046/j.1540.8167.90301.x">One-dimensional rabbit sinoatrial node models: benefits and limitations</ulink>, A. Garny, P. Kohl, P.J. Hunter, M.R. Boyett and D. Noble, 2003, <ulink url="http://www.blackwellpublishing.com/journal.asp?ref=1045-3873&site=1">
<emphasis>The Journal of Cardiovascular Electrophysiology</emphasis>
</ulink>, 14, S121-S132. (<ulink url="http://www.blackwell-synergy.com/doi/full/10.1046/j.1540.8167.90301.x">Full text</ulink> and PDF versions of the article are available on The Journal of Cardiovascular Electrophysiology website for journal subscribers.) <ulink url="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10899081&dopt=Abstract">PubMed ID: 14760914</ulink>
</para>
<informalfigure float="0" id="fig_cell_diagram">
<mediaobject>
<imageobject>
<objectinfo>
<title>cell diagram of the Zhang et al SAN model showing ionic currents, pumps and exchangers within the sarcolemma and the sarcoplasmic reticulum</title>
</objectinfo>
<imagedata fileref="zhang_2000.png"/>
</imageobject>
</mediaobject>
<caption>A schematic diagram describing the current flows across the cell membrane that are captured in the Garny <emphasis>et al</emphasis> 2003 'published' and "0D capable' models of the action potentials in the cells of the SA node. The 1D capable model has one additional current called I_Cap - or a persistant calcium current.</caption>
</informalfigure>
</sect1>
</article>
</documentation>
<units name="per_second">
<unit units="second" exponent="-1"/>
</units>
<units name="millivolt">
<unit units="volt" prefix="milli"/>
</units>
<units name="per_millivolt">
<unit units="volt" prefix="milli" exponent="-1"/>
</units>
<units name="per_millivolt_second">
<unit units="millivolt" exponent="-1"/>
<unit units="second" exponent="-1"/>
</units>
<units name="microS">
<unit units="siemens" prefix="micro"/>
</units>
<units name="microF">
<unit units="farad" prefix="micro"/>
</units>
<units name="nanoA">
<unit units="ampere" prefix="nano"/>
</units>
<units name="millimolar">
<unit units="mole" prefix="milli"/>
<unit units="litre" exponent="-1"/>
</units>
<units name="millimolar4">
<unit units="millimolar" exponent="4"/>
</units>
<units name="millijoule_per_mole_kelvin">
<unit units="joule" prefix="milli"/>
<unit units="mole" exponent="-1"/>
<unit units="kelvin" exponent="-1"/>
</units>
<units name="coulomb_per_mole">
<unit units="coulomb"/>
<unit units="mole" exponent="-1"/>
</units>
<units name="microlitre_per_second">
<unit units="litre" prefix="micro"/>
<unit units="second" exponent="-1"/>
</units>
<component name="environment">
<variable units="second" public_interface="out" name="time"/>
</component>
<component name="membrane">
<variable units="dimensionless" public_interface="out" name="Version" initial_value="1"/>
<variable units="dimensionless" public_interface="out" name="dCell" initial_value="0"/>
<variable units="dimensionless" public_interface="out" name="FCellConstant" initial_value="1.0309347"/>
<variable units="dimensionless" public_interface="out" name="FCell"/>
<variable units="millivolt" public_interface="out" name="V" initial_value="-39.013558536"/>
<variable units="millijoule_per_mole_kelvin" public_interface="out" name="R" initial_value="8314"/>
<variable units="kelvin" public_interface="out" name="T" initial_value="310"/>
<variable units="coulomb_per_mole" public_interface="out" name="F" initial_value="96845"/>
<variable units="microF" name="Cm"/>
<variable units="microF" name="CmCentre" initial_value="2e-5"/>
<variable units="microF" name="CmPeriphery" initial_value="6.5e-5"/>
<variable units="second" public_interface="in" name="time"/>
<variable units="nanoA" public_interface="in" name="i_Na"/>
<variable units="nanoA" public_interface="in" name="i_Ca_L"/>
<variable units="nanoA" public_interface="in" name="i_Ca_T"/>
<variable units="nanoA" public_interface="in" name="i_to"/>
<variable units="nanoA" public_interface="in" name="i_sus"/>
<variable units="nanoA" public_interface="in" name="i_K_r"/>
<variable units="nanoA" public_interface="in" name="i_K_s"/>
<variable units="nanoA" public_interface="in" name="i_f_Na"/>
<variable units="nanoA" public_interface="in" name="i_f_K"/>
<variable units="nanoA" public_interface="in" name="i_b_Na"/>
<variable units="nanoA" public_interface="in" name="i_b_Ca"/>
<variable units="nanoA" public_interface="in" name="i_b_K"/>
<variable units="nanoA" public_interface="in" name="i_NaCa"/>
<variable units="nanoA" public_interface="in" name="i_p"/>
<variable units="nanoA" public_interface="in" name="i_Ca_p"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>FCell</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">1.07</cn>
<apply>
<minus/>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<ci>dCell</ci>
</apply>
<cn cellml:units="dimensionless">0.1</cn>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.7745</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<ci>dCell</ci>
</apply>
<cn cellml:units="dimensionless">2.05</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">0.295</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<divide/>
<apply>
<times/>
<ci>FCellConstant</ci>
<ci>dCell</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.7745</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<ci>dCell</ci>
</apply>
<cn cellml:units="dimensionless">2.05</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">0.295</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">1.07</cn>
<cn cellml:units="dimensionless">29</cn>
<ci>dCell</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">30</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.7745</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<cn cellml:units="dimensionless">29</cn>
<ci>dCell</ci>
</apply>
<cn cellml:units="dimensionless">24.5</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1.95</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>Cm</ci>
<apply>
<plus/>
<ci>CmCentre</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>CmPeriphery</ci>
<ci>CmCentre</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V</ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
<ci>Cm</ci>
</apply>
<apply>
<plus/>
<ci>i_Na</ci>
<ci>i_Ca_L</ci>
<ci>i_Ca_T</ci>
<ci>i_to</ci>
<ci>i_sus</ci>
<ci>i_K_r</ci>
<ci>i_K_s</ci>
<ci>i_f_Na</ci>
<ci>i_f_K</ci>
<ci>i_b_Na</ci>
<ci>i_b_Ca</ci>
<ci>i_b_K</ci>
<ci>i_NaCa</ci>
<ci>i_p</ci>
<ci>i_Ca_p</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="sodium_current">
<variable units="dimensionless" public_interface="in" private_interface="out" name="Version"/>
<variable units="dimensionless" public_interface="in" name="FCell"/>
<variable units="nanoA" public_interface="out" name="i_Na"/>
<variable units="microlitre_per_second" name="g_Na"/>
<variable units="microlitre_per_second" name="g_Na_Centre_Published" initial_value="0"/>
<variable units="microlitre_per_second" name="g_Na_Centre_0DCapable" initial_value="0"/>
<variable units="microlitre_per_second" name="g_Na_Centre_1DCapable" initial_value="0"/>
<variable units="microlitre_per_second" name="g_Na_Periphery_Published" initial_value="1.2e-6"/>
<variable units="microlitre_per_second" name="g_Na_Periphery_0DCapable" initial_value="1.204e-6"/>
<variable units="microlitre_per_second" name="g_Na_Periphery_1DCapable" initial_value="3.7e-7"/>
<variable units="millivolt" public_interface="in" name="E_Na"/>
<variable units="millimolar" public_interface="in" name="Na_o"/>
<variable units="millijoule_per_mole_kelvin" public_interface="in" name="R"/>
<variable units="coulomb_per_mole" public_interface="in" name="F"/>
<variable units="kelvin" public_interface="in" name="T"/>
<variable units="second" public_interface="in" private_interface="out" name="time"/>
<variable units="millivolt" public_interface="in" private_interface="out" name="V"/>
<variable units="dimensionless" private_interface="in" name="m"/>
<variable units="dimensionless" private_interface="in" name="h"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>g_Na</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>g_Na_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_Na_Periphery_Published</ci>
<ci>g_Na_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>g_Na_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_Na_Periphery_0DCapable</ci>
<ci>g_Na_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>g_Na_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_Na_Periphery_1DCapable</ci>
<ci>g_Na_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>i_Na</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>g_Na</ci>
<apply>
<power/>
<ci>m</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<ci>h</ci>
<ci>Na_o</ci>
<apply>
<power/>
<ci>F</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>V</ci>
<ci>E_Na</ci>
</apply>
<ci>F</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<ci>V</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<ci>V</ci>
</apply>
</apply>
</math>
</component>
<component name="sodium_current_m_gate">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="out" name="m" initial_value="0.092361701692"/>
<variable units="dimensionless" name="m_infinity"/>
<variable units="second" name="tau_m"/>
<variable units="millivolt" public_interface="in" name="V"/>
<variable units="second" public_interface="in" name="time"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>m</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>m_infinity</ci>
<ci>m</ci>
</apply>
<ci>tau_m</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>m_infinity</ci>
<piecewise>
<piece>
<apply>
<power/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
</apply>
<cn cellml:units="millivolt">5.46</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<cn cellml:units="dimensionless">3</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<otherwise>
<apply>
<power/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">30.32</cn>
</apply>
</apply>
<cn cellml:units="millivolt">5.46</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<cn cellml:units="dimensionless">3</cn>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>tau_m</ci>
<piecewise>
<piece>
<apply>
<plus/>
<apply>
<divide/>
<cn cellml:units="second">0.0006247</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.832</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.335</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">56.7</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.627</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.082</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">65.01</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="second">4e-5</cn>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<apply>
<divide/>
<cn cellml:units="second">0.0006247</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.8322166</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.33566</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">56.7062</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.6274</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.0823</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">65.0131</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="second">4.569e-5</cn>
</apply>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<component name="sodium_current_h_gate">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="out" name="h"/>
<variable units="dimensionless" name="F_Na"/>
<variable units="dimensionless" name="h1" initial_value="0.015905380261"/>
<variable units="dimensionless" name="h2" initial_value="0.01445216109"/>
<variable units="dimensionless" name="h1_infinity"/>
<variable units="dimensionless" name="h2_infinity"/>
<variable units="second" name="tau_h1"/>
<variable units="second" name="tau_h2"/>
<variable units="millivolt" public_interface="in" name="V"/>
<variable units="second" public_interface="in" name="time"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>F_Na</ci>
<piecewise>
<piece>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.0952</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.063</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">34.4</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">1.66</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.225</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">63.7</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">0.0869</cn>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.09518</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.06306</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">34.4</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">1.662</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.2251</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">63.7</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">0.08693</cn>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>h</ci>
<apply>
<plus/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>F_Na</ci>
</apply>
<ci>h1</ci>
</apply>
<apply>
<times/>
<ci>F_Na</ci>
<ci>h2</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>h1</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>h1_infinity</ci>
<ci>h1</ci>
</apply>
<ci>tau_h1</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>h2</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>h2_infinity</ci>
<ci>h2</ci>
</apply>
<ci>tau_h2</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h1_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">66.1</cn>
</apply>
<cn cellml:units="millivolt">6.4</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>h2_infinity</ci>
<ci>h1_infinity</ci>
</apply>
<apply>
<eq/>
<ci>tau_h1</ci>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="second">3.717e-6</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.2815</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">17.11</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.003732</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.3426</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">37.76</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="second">0.0005977</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_h2</ci>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="second">3.186e-8</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.6219</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">18.8</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">7.189e-5</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.6683</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">34.07</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="second">0.003556</cn>
</apply>
</apply>
</math>
</component>
<component name="L_type_Ca_channel">
<variable units="dimensionless" public_interface="in" private_interface="out" name="Version"/>
<variable units="dimensionless" public_interface="in" private_interface="out" name="FCell"/>
<variable units="nanoA" public_interface="out" name="i_Ca_L"/>
<variable units="microS" name="g_Ca_L_Centre_Published" initial_value="0.0058"/>
<variable units="microS" name="g_Ca_L_Centre_0DCapable" initial_value="0.0057938"/>
<variable units="microS" name="g_Ca_L_Centre_1DCapable" initial_value="0.0082"/>
<variable units="microS" name="g_Ca_L_Periphery_Published" initial_value="0.0659"/>
<variable units="microS" name="g_Ca_L_Periphery_0DCapable" initial_value="0.06588648"/>
<variable units="microS" name="g_Ca_L_Periphery_1DCapable" initial_value="0.0659"/>
<variable units="microS" name="g_Ca_L"/>
<variable units="millivolt" name="E_Ca_L" initial_value="46.4"/>
<variable units="second" public_interface="in" private_interface="out" name="time"/>
<variable units="millivolt" public_interface="in" private_interface="out" name="V"/>
<variable units="dimensionless" private_interface="in" name="d_L"/>
<variable units="dimensionless" private_interface="in" name="f_L"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>g_Ca_L</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>g_Ca_L_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_Ca_L_Periphery_Published</ci>
<ci>g_Ca_L_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>g_Ca_L_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_Ca_L_Periphery_0DCapable</ci>
<ci>g_Ca_L_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>g_Ca_L_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_Ca_L_Periphery_1DCapable</ci>
<ci>g_Ca_L_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>i_Ca_L</ci>
<apply>
<times/>
<ci>g_Ca_L</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>f_L</ci>
<ci>d_L</ci>
</apply>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.006</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">14.1</cn>
</apply>
</apply>
<cn cellml:units="millivolt">6</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>E_Ca_L</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="L_type_Ca_channel_d_gate">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="in" name="FCell"/>
<variable units="dimensionless" public_interface="out" name="d_L" initial_value="0.04804900895"/>
<variable units="per_second" name="alpha_d_L"/>
<variable units="per_second" name="beta_d_L"/>
<variable units="dimensionless" name="d_L_infinity"/>
<variable units="second" name="tau_d_L"/>
<variable units="millivolt" public_interface="in" name="V"/>
<variable units="second" public_interface="in" name="time"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>d_L</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>d_L_infinity</ci>
<ci>d_L</ci>
</apply>
<ci>tau_d_L</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_d_L</ci>
<piecewise>
<piece>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt_second">28.38</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">35</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">35</cn>
</apply>
</apply>
<cn cellml:units="millivolt">2.5</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millivolt_second">84.9</cn>
<ci>V</ci>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.208</cn>
</apply>
<ci>V</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt_second">28.39</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">35</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">35</cn>
</apply>
</apply>
<cn cellml:units="millivolt">2.5</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millivolt_second">84.9</cn>
<ci>V</ci>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.208</cn>
</apply>
<ci>V</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt_second">28.4</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">35</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">35</cn>
</apply>
</apply>
<cn cellml:units="millivolt">2.5</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millivolt_second">84.9</cn>
<ci>V</ci>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.208</cn>
</apply>
<ci>V</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>beta_d_L</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millivolt_second">11.43</cn>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">5</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.4</cn>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">5</cn>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millivolt_second">11.42</cn>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">5</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.4</cn>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">5</cn>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>tau_d_L</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">2</cn>
<apply>
<plus/>
<ci>alpha_d_L</ci>
<ci>beta_d_L</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>d_L_infinity</ci>
<piecewise>
<piece>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">23.1</cn>
</apply>
</apply>
<cn cellml:units="millivolt">6</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">22.3</cn>
<apply>
<times/>
<cn cellml:units="millivolt">0.8</cn>
<ci>FCell</ci>
</apply>
</apply>
</apply>
<cn cellml:units="millivolt">6</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">22.2</cn>
</apply>
</apply>
<cn cellml:units="millivolt">6</cn>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<component name="L_type_Ca_channel_f_gate">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="in" name="FCell"/>
<variable units="dimensionless" public_interface="out" name="f_L" initial_value="0.48779845203"/>
<variable units="per_second" name="alpha_f_L"/>
<variable units="per_second" name="beta_f_L"/>
<variable units="dimensionless" name="f_L_infinity"/>
<variable units="second" name="tau_f_L"/>
<variable units="millivolt" public_interface="in" name="V"/>
<variable units="second" public_interface="in" name="time"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>f_L</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>f_L_infinity</ci>
<ci>f_L</ci>
</apply>
<ci>tau_f_L</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_f_L</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millivolt_second">3.75</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">28</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">28</cn>
</apply>
<cn cellml:units="millivolt">4</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millivolt_second">3.12</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">28</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">28</cn>
</apply>
<cn cellml:units="millivolt">4</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>beta_f_L</ci>
<piecewise>
<piece>
<apply>
<divide/>
<cn cellml:units="per_second">30</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">28</cn>
</apply>
</apply>
<cn cellml:units="millivolt">4</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<cn cellml:units="per_second">25</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">28</cn>
</apply>
</apply>
<cn cellml:units="millivolt">4</cn>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>tau_f_L</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.2</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.2</cn>
<ci>FCell</ci>
</apply>
</apply>
<apply>
<plus/>
<ci>alpha_f_L</ci>
<ci>beta_f_L</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>alpha_f_L</ci>
<ci>beta_f_L</ci>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>f_L_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">45</cn>
</apply>
<cn cellml:units="millivolt">5</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="T_type_Ca_channel">
<variable units="dimensionless" public_interface="in" private_interface="out" name="Version"/>
<variable units="dimensionless" public_interface="in" private_interface="out" name="FCell"/>
<variable units="nanoA" public_interface="out" name="i_Ca_T"/>
<variable units="microS" name="g_Ca_T_Centre_Published" initial_value="0.0043"/>
<variable units="microS" name="g_Ca_T_Centre_0DCapable" initial_value="0.00427806"/>
<variable units="microS" name="g_Ca_T_Centre_1DCapable" initial_value="0.0021"/>
<variable units="microS" name="g_Ca_T_Periphery_Published" initial_value="0.0139"/>
<variable units="microS" name="g_Ca_T_Periphery_0DCapable" initial_value="0.0138823"/>
<variable units="microS" name="g_Ca_T_Periphery_1DCapable" initial_value="0.00694"/>
<variable units="microS" name="g_Ca_T"/>
<variable units="millivolt" name="E_Ca_T" initial_value="45"/>
<variable units="second" public_interface="in" private_interface="out" name="time"/>
<variable units="millivolt" public_interface="in" private_interface="out" name="V"/>
<variable units="dimensionless" private_interface="in" name="d_T"/>
<variable units="dimensionless" private_interface="in" name="f_T"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>g_Ca_T</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>g_Ca_T_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_Ca_T_Periphery_Published</ci>
<ci>g_Ca_T_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>g_Ca_T_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_Ca_T_Periphery_0DCapable</ci>
<ci>g_Ca_T_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>g_Ca_T_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_Ca_T_Periphery_1DCapable</ci>
<ci>g_Ca_T_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>i_Ca_T</ci>
<apply>
<times/>
<ci>g_Ca_T</ci>
<ci>d_T</ci>
<ci>f_T</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_Ca_T</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="T_type_Ca_channel_d_gate">
<variable units="dimensionless" public_interface="out" name="d_T" initial_value="0.42074047435"/>
<variable units="per_second" name="alpha_d_T"/>
<variable units="per_second" name="beta_d_T"/>
<variable units="dimensionless" name="d_T_infinity"/>
<variable units="second" name="tau_d_T"/>
<variable units="millivolt" public_interface="in" name="V"/>
<variable units="second" public_interface="in" name="time"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>d_T</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>d_T_infinity</ci>
<ci>d_T</ci>
</apply>
<ci>tau_d_T</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_d_T</ci>
<apply>
<times/>
<cn cellml:units="per_second">1068</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">26.3</cn>
</apply>
<cn cellml:units="millivolt">30</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_d_T</ci>
<apply>
<times/>
<cn cellml:units="per_second">1068</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">26.3</cn>
</apply>
</apply>
<cn cellml:units="millivolt">30</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_d_T</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>alpha_d_T</ci>
<ci>beta_d_T</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>d_T_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">37</cn>
</apply>
</apply>
<cn cellml:units="millivolt">6.8</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="T_type_Ca_channel_f_gate">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="in" name="FCell"/>
<variable units="dimensionless" public_interface="out" name="f_T" initial_value="0.038968420558"/>
<variable units="per_second" name="alpha_f_T"/>
<variable units="per_second" name="beta_f_T"/>
<variable units="dimensionless" name="f_T_infinity"/>
<variable units="second" name="tau_f_T"/>
<variable units="millivolt" public_interface="in" name="V"/>
<variable units="second" public_interface="in" name="time"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>f_T</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>f_T_infinity</ci>
<ci>f_T</ci>
</apply>
<ci>tau_f_T</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_f_T</ci>
<piecewise>
<piece>
<apply>
<times/>
<cn cellml:units="per_second">15.3</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">71</cn>
<apply>
<times/>
<cn cellml:units="millivolt">0.7</cn>
<ci>FCell</ci>
</apply>
</apply>
</apply>
<cn cellml:units="millivolt">83.3</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<times/>
<cn cellml:units="per_second">15.3</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">71.7</cn>
</apply>
</apply>
<cn cellml:units="millivolt">83.3</cn>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>beta_f_T</ci>
<piecewise>
<piece>
<apply>
<times/>
<cn cellml:units="per_second">15</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">71</cn>
</apply>
<cn cellml:units="millivolt">15.38</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<times/>
<cn cellml:units="per_second">15</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">71.7</cn>
</apply>
<cn cellml:units="millivolt">15.38</cn>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>tau_f_T</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>alpha_f_T</ci>
<ci>beta_f_T</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>f_T_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">71</cn>
</apply>
<cn cellml:units="millivolt">9</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="four_AP_sensitive_currents">
<variable units="dimensionless" public_interface="in" private_interface="out" name="Version"/>
<variable units="dimensionless" public_interface="in" private_interface="out" name="FCell"/>
<variable units="nanoA" public_interface="out" name="i_to"/>
<variable units="nanoA" public_interface="out" name="i_sus"/>
<variable units="microS" name="g_to_Centre_Published" initial_value="0.00491"/>
<variable units="microS" name="g_to_Centre_0DCapable" initial_value="0.004905"/>
<variable units="microS" name="g_to_Centre_1DCapable" initial_value="0.004905"/>
<variable units="microS" name="g_to_Periphery_Published" initial_value="0.03649"/>
<variable units="microS" name="g_to_Periphery_0DCapable" initial_value="0.036495"/>
<variable units="microS" name="g_to_Periphery_1DCapable" initial_value="0.0365"/>
<variable units="microS" name="g_to"/>
<variable units="microS" name="g_sus_Centre_Published" initial_value="6.65e-5"/>
<variable units="microS" name="g_sus_Centre_0DCapable" initial_value="6.645504e-5"/>
<variable units="microS" name="g_sus_Centre_1DCapable" initial_value="0.000266"/>
<variable units="microS" name="g_sus_Periphery_Published" initial_value="0.0114"/>
<variable units="microS" name="g_sus_Periphery_0DCapable" initial_value="0.01138376"/>
<variable units="microS" name="g_sus_Periphery_1DCapable" initial_value="0.0114"/>
<variable units="microS" name="g_sus"/>
<variable units="millivolt" public_interface="in" name="E_K"/>
<variable units="millivolt" public_interface="in" private_interface="out" name="V"/>
<variable units="second" public_interface="in" private_interface="out" name="time"/>
<variable units="dimensionless" private_interface="in" name="q"/>
<variable units="dimensionless" private_interface="in" name="r"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>g_to</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>g_to_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_to_Periphery_Published</ci>
<ci>g_to_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>g_to_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_to_Periphery_0DCapable</ci>
<ci>g_to_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>g_to_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_to_Periphery_1DCapable</ci>
<ci>g_to_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>g_sus</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>g_sus_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_sus_Periphery_Published</ci>
<ci>g_sus_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>g_sus_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_sus_Periphery_0DCapable</ci>
<ci>g_sus_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>g_sus_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_sus_Periphery_1DCapable</ci>
<ci>g_sus_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>i_to</ci>
<apply>
<times/>
<ci>g_to</ci>
<ci>q</ci>
<ci>r</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>i_sus</ci>
<apply>
<times/>
<ci>g_sus</ci>
<ci>r</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="four_AP_sensitive_currents_q_gate">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="in" name="FCell"/>
<variable units="dimensionless" public_interface="out" name="q" initial_value="0.29760539675"/>
<variable units="dimensionless" name="q_infinity"/>
<variable units="second" name="tau_q"/>
<variable units="millivolt" public_interface="in" name="V"/>
<variable units="second" public_interface="in" name="time"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>q_infinity</ci>
<ci>q</ci>
</apply>
<ci>tau_q</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">59.37</cn>
</apply>
<cn cellml:units="millivolt">13.1</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_q</ci>
<piecewise>
<piece>
<apply>
<plus/>
<cn cellml:units="second">0.0101</cn>
<apply>
<divide/>
<cn cellml:units="second">0.06517</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.57</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.08</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">49</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="second">2.4e-5</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.1</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">50.93</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.001</cn>
<cn cellml:units="dimensionless">3</cn>
</apply>
<apply>
<plus/>
<cn cellml:units="second">30.31</cn>
<apply>
<divide/>
<cn cellml:units="second">195.5</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.5686</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.08161</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">39</cn>
<apply>
<times/>
<cn cellml:units="millivolt">10</cn>
<ci>FCell</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.7174</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">0.2719</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.1719</cn>
<ci>FCell</ci>
</apply>
</apply>
<cn cellml:units="per_millivolt">1</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">40.93</cn>
<apply>
<times/>
<cn cellml:units="millivolt">10</cn>
<ci>FCell</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<cn cellml:units="second">0.0101</cn>
<apply>
<divide/>
<cn cellml:units="second">0.06517</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.5686</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.08161</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">39</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.7174</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.2719</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">40.93</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<component name="four_AP_sensitive_currents_r_gate">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="out" name="r" initial_value="0.064402950262"/>
<variable units="dimensionless" name="r_infinity"/>
<variable units="second" name="tau_r"/>
<variable units="millivolt" public_interface="in" name="V"/>
<variable units="second" public_interface="in" name="time"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>r</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>r_infinity</ci>
<ci>r</ci>
</apply>
<ci>tau_r</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>r_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">10.93</cn>
</apply>
</apply>
<cn cellml:units="millivolt">19.7</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_r</ci>
<piecewise>
<piece>
<apply>
<times/>
<cn cellml:units="dimensionless">0.001</cn>
<apply>
<plus/>
<cn cellml:units="second">2.98</cn>
<apply>
<divide/>
<cn cellml:units="second">15.59</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">1.037</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.09</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">30.61</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.369</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.12</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">23.84</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<times/>
<cn cellml:units="dimensionless">0.0025</cn>
<apply>
<plus/>
<cn cellml:units="second">1.191</cn>
<apply>
<divide/>
<cn cellml:units="second">7.838</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">1.037</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.09012</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">30.61</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.369</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.119</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">23.84</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<times/>
<cn cellml:units="dimensionless">0.001</cn>
<apply>
<plus/>
<cn cellml:units="second">2.98</cn>
<apply>
<divide/>
<cn cellml:units="second">19.59</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">1.037</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.09012</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">30.61</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.369</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.119</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">23.84</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<component name="rapid_delayed_rectifying_potassium_current">
<variable units="dimensionless" public_interface="in" private_interface="out" name="Version"/>
<variable units="dimensionless" public_interface="in" name="FCell"/>
<variable units="nanoA" public_interface="out" name="i_K_r"/>
<variable units="microS" name="g_K_r_Centre_Published" initial_value="0.000797"/>
<variable units="microS" name="g_K_r_Centre_0DCapable" initial_value="0.00079704"/>
<variable units="microS" name="g_K_r_Centre_1DCapable" initial_value="0.000738"/>
<variable units="microS" name="g_K_r_Periphery_Published" initial_value="0.016"/>
<variable units="microS" name="g_K_r_Periphery_0DCapable" initial_value="0.016"/>
<variable units="microS" name="g_K_r_Periphery_1DCapable" initial_value="0.0208"/>
<variable units="microS" name="g_K_r"/>
<variable units="dimensionless" name="P_a"/>
<variable units="millivolt" public_interface="in" name="E_K"/>
<variable units="second" public_interface="in" private_interface="out" name="time"/>
<variable units="millivolt" public_interface="in" private_interface="out" name="V"/>
<variable units="dimensionless" private_interface="in" name="P_af"/>
<variable units="dimensionless" private_interface="in" name="P_as"/>
<variable units="dimensionless" private_interface="in" name="P_i"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>g_K_r</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>g_K_r_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_K_r_Periphery_Published</ci>
<ci>g_K_r_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>g_K_r_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_K_r_Periphery_0DCapable</ci>
<ci>g_K_r_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>g_K_r_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_K_r_Periphery_1DCapable</ci>
<ci>g_K_r_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>i_K_r</ci>
<apply>
<times/>
<ci>g_K_r</ci>
<ci>P_a</ci>
<ci>P_i</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>P_a</ci>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.6</cn>
<ci>P_af</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.4</cn>
<ci>P_as</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="rapid_delayed_rectifying_potassium_current_P_af_gate">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="out" name="P_af" initial_value="0.13034201158"/>
<variable units="dimensionless" public_interface="out" name="P_af_infinity"/>
<variable units="second" name="tau_P_af"/>
<variable units="millivolt" public_interface="in" name="V"/>
<variable units="second" public_interface="in" name="time"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>P_af</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_af_infinity</ci>
<ci>P_af</ci>
</apply>
<ci>tau_P_af</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>P_af_infinity</ci>
<piecewise>
<piece>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">14.2</cn>
</apply>
</apply>
<cn cellml:units="millivolt">10.6</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<neq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">13.2</cn>
</apply>
</apply>
<cn cellml:units="millivolt">10.6</cn>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>tau_P_af</ci>
<piecewise>
<piece>
<apply>
<divide/>
<cn cellml:units="second">1</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">37.2</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">9</cn>
</apply>
<cn cellml:units="millivolt">15.9</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.96</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">9</cn>
</apply>
</apply>
<cn cellml:units="millivolt">22.5</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<neq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<cn cellml:units="second">1</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">37.2</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">10</cn>
</apply>
<cn cellml:units="millivolt">15.9</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.96</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn cellml:units="millivolt">22.5</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<component name="rapid_delayed_rectifying_potassium_current_P_as_gate">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="out" name="P_as" initial_value="0.46960956028"/>
<variable units="dimensionless" name="P_as_infinity"/>
<variable units="second" name="tau_P_as"/>
<variable units="dimensionless" public_interface="in" name="P_af_infinity"/>
<variable units="millivolt" public_interface="in" name="V"/>
<variable units="second" public_interface="in" name="time"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>P_as</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_as_infinity</ci>
<ci>P_as</ci>
</apply>
<ci>tau_P_as</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>P_as_infinity</ci>
<ci>P_af_infinity</ci>
</apply>
<apply>
<eq/>
<ci>tau_P_as</ci>
<piecewise>
<piece>
<apply>
<divide/>
<cn cellml:units="second">1</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">4.2</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">9</cn>
</apply>
<cn cellml:units="millivolt">17</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.15</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">9</cn>
</apply>
</apply>
<cn cellml:units="millivolt">21.6</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<neq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<cn cellml:units="second">1</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">4.2</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">10</cn>
</apply>
<cn cellml:units="millivolt">17</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.15</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn cellml:units="millivolt">21.6</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<component name="rapid_delayed_rectifying_potassium_current_P_i_gate">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="out" name="P_i" initial_value="0.87993375273"/>
<variable units="dimensionless" name="P_i_infinity"/>
<variable units="second" name="tau_P_i"/>
<variable units="millivolt" public_interface="in" name="V"/>
<variable units="second" public_interface="in" name="time"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>tau_P_i</ci>
<piecewise>
<piece>
<cn cellml:units="second">0.002</cn>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<cn cellml:units="second">0.002</cn>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<cn cellml:units="second">0.006</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>P_i</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_i_infinity</ci>
<ci>P_i</ci>
</apply>
<ci>tau_P_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>P_i_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">18.6</cn>
</apply>
<cn cellml:units="millivolt">10.1</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="slow_delayed_rectifying_potassium_current">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="in" name="FCell"/>
<variable units="nanoA" public_interface="out" name="i_K_s"/>
<variable units="microS" name="g_K_s_Centre_Published" initial_value="0.000518"/>
<variable units="microS" name="g_K_s_Centre_0DCapable" initial_value="0.0003445"/>
<variable units="microS" name="g_K_s_Centre_1DCapable" initial_value="0.000345"/>
<variable units="microS" name="g_K_s_Periphery_Published" initial_value="0.0104"/>
<variable units="microS" name="g_K_s_Periphery_0DCapable" initial_value="0.0104"/>
<variable units="microS" name="g_K_s_Periphery_1DCapable" initial_value="0.0104"/>
<variable units="microS" name="g_K_s"/>
<variable units="millivolt" public_interface="in" name="E_K_s"/>
<variable units="second" public_interface="in" private_interface="out" name="time"/>
<variable units="millivolt" public_interface="in" private_interface="out" name="V"/>
<variable units="dimensionless" private_interface="in" name="xs"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>g_K_s</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>g_K_s_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_K_s_Periphery_Published</ci>
<ci>g_K_s_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>g_K_s_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_K_s_Periphery_0DCapable</ci>
<ci>g_K_s_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>g_K_s_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_K_s_Periphery_1DCapable</ci>
<ci>g_K_s_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>i_K_s</ci>
<apply>
<times/>
<ci>g_K_s</ci>
<apply>
<power/>
<ci>xs</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K_s</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="slow_delayed_rectifying_potassium_current_xs_gate">
<variable units="dimensionless" public_interface="out" name="xs" initial_value="0.082293827208"/>
<variable units="per_second" name="alpha_xs"/>
<variable units="per_second" name="beta_xs"/>
<variable units="millivolt" public_interface="in" name="V"/>
<variable units="second" public_interface="in" name="time"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>xs</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>alpha_xs</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>xs</ci>
</apply>
</apply>
<apply>
<times/>
<ci>beta_xs</ci>
<ci>xs</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_xs</ci>
<apply>
<divide/>
<cn cellml:units="per_second">14</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">40</cn>
</apply>
</apply>
<cn cellml:units="millivolt">9</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_xs</ci>
<apply>
<times/>
<cn cellml:units="per_second">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
</apply>
<cn cellml:units="millivolt">45</cn>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="hyperpolarisation_activated_current">
<variable units="dimensionless" public_interface="in" private_interface="out" name="Version"/>
<variable units="dimensionless" public_interface="in" name="FCell"/>
<variable units="nanoA" public_interface="out" name="i_f_Na"/>
<variable units="nanoA" public_interface="out" name="i_f_K"/>
<variable units="microS" name="g_f_Na_Centre_Published" initial_value="0.000548"/>
<variable units="microS" name="g_f_Na_Centre_0DCapable" initial_value="0.0005465"/>
<variable units="microS" name="g_f_Na_Centre_1DCapable" initial_value="0.000437"/>
<variable units="microS" name="g_f_Na_Periphery_Published" initial_value="0.0069"/>
<variable units="microS" name="g_f_Na_Periphery_0DCapable" initial_value="0.006875"/>
<variable units="microS" name="g_f_Na_Periphery_1DCapable" initial_value="0.0055"/>
<variable units="microS" name="g_f_Na"/>
<variable units="microS" name="g_f_K_Centre_Published" initial_value="0.000548"/>
<variable units="microS" name="g_f_K_Centre_0DCapable" initial_value="0.0005465"/>
<variable units="microS" name="g_f_K_Centre_1DCapable" initial_value="0.000437"/>
<variable units="microS" name="g_f_K_Periphery_Published" initial_value="0.0069"/>
<variable units="microS" name="g_f_K_Periphery_0DCapable" initial_value="0.006875"/>
<variable units="microS" name="g_f_K_Periphery_1DCapable" initial_value="0.0055"/>
<variable units="microS" name="g_f_K"/>
<variable units="millivolt" public_interface="in" name="E_K"/>
<variable units="millivolt" public_interface="in" name="E_Na"/>
<variable units="second" public_interface="in" private_interface="out" name="time"/>
<variable units="millivolt" public_interface="in" private_interface="out" name="V"/>
<variable units="dimensionless" private_interface="in" name="y"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>g_f_Na</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>g_f_Na_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_f_Na_Periphery_Published</ci>
<ci>g_f_Na_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>g_f_Na_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_f_Na_Periphery_0DCapable</ci>
<ci>g_f_Na_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>g_f_Na_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_f_Na_Periphery_1DCapable</ci>
<ci>g_f_Na_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>i_f_Na</ci>
<piecewise>
<piece>
<apply>
<times/>
<ci>g_f_Na</ci>
<ci>y</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_Na</ci>
</apply>
</apply>
<apply>
<neq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</piece>
<otherwise>
<apply>
<times/>
<ci>g_f_Na</ci>
<ci>y</ci>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">77.6</cn>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>g_f_K</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>g_f_K_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_f_K_Periphery_Published</ci>
<ci>g_f_K_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>g_f_K_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_f_K_Periphery_0DCapable</ci>
<ci>g_f_K_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>g_f_K_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_f_K_Periphery_1DCapable</ci>
<ci>g_f_K_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>i_f_K</ci>
<piecewise>
<piece>
<apply>
<times/>
<ci>g_f_K</ci>
<ci>y</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
<apply>
<neq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</piece>
<otherwise>
<apply>
<times/>
<ci>g_f_K</ci>
<ci>y</ci>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">102</cn>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<component name="hyperpolarisation_activated_current_y_gate">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="out" name="y" initial_value="0.03889291759"/>
<variable units="per_second" name="alpha_y"/>
<variable units="per_second" name="beta_y"/>
<variable units="millivolt" public_interface="in" name="V"/>
<variable units="second" public_interface="in" name="time"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>y</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>alpha_y</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>y</ci>
</apply>
</apply>
<apply>
<times/>
<ci>beta_y</ci>
<ci>y</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_y</ci>
<piecewise>
<piece>
<apply>
<times/>
<cn cellml:units="per_second">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">78.91</cn>
</apply>
</apply>
<cn cellml:units="millivolt">26.62</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<otherwise>
<apply>
<times/>
<cn cellml:units="per_second">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">78.91</cn>
</apply>
</apply>
<cn cellml:units="millivolt">26.63</cn>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>beta_y</ci>
<apply>
<times/>
<cn cellml:units="per_second">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">75.13</cn>
</apply>
<cn cellml:units="millivolt">21.25</cn>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="sodium_background_current">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="in" name="FCell"/>
<variable units="nanoA" public_interface="out" name="i_b_Na"/>
<variable units="microS" name="g_b_Na_Centre_Published" initial_value="5.8e-5"/>
<variable units="microS" name="g_b_Na_Centre_0DCapable" initial_value="5.81818e-5"/>
<variable units="microS" name="g_b_Na_Centre_1DCapable" initial_value="5.8e-5"/>
<variable units="microS" name="g_b_Na_Periphery_Published" initial_value="0.000189"/>
<variable units="microS" name="g_b_Na_Periphery_0DCapable" initial_value="0.0001888"/>
<variable units="microS" name="g_b_Na_Periphery_1DCapable" initial_value="0.000189"/>
<variable units="microS" name="g_b_Na"/>
<variable units="millivolt" public_interface="in" name="E_Na"/>
<variable units="millivolt" public_interface="in" name="V"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>g_b_Na</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>g_b_Na_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_b_Na_Periphery_Published</ci>
<ci>g_b_Na_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>g_b_Na_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_b_Na_Periphery_0DCapable</ci>
<ci>g_b_Na_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>g_b_Na_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_b_Na_Periphery_1DCapable</ci>
<ci>g_b_Na_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>i_b_Na</ci>
<apply>
<times/>
<ci>g_b_Na</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_Na</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="potassium_background_current">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="in" name="FCell"/>
<variable units="nanoA" public_interface="out" name="i_b_K"/>
<variable units="microS" name="g_b_K_Centre_Published" initial_value="2.52e-5"/>
<variable units="microS" name="g_b_K_Centre_0DCapable" initial_value="2.523636e-5"/>
<variable units="microS" name="g_b_K_Centre_1DCapable" initial_value="2.52e-5"/>
<variable units="microS" name="g_b_K_Periphery_Published" initial_value="8.19e-5"/>
<variable units="microS" name="g_b_K_Periphery_0DCapable" initial_value="8.1892e-5"/>
<variable units="microS" name="g_b_K_Periphery_1DCapable" initial_value="8.19e-5"/>
<variable units="microS" name="g_b_K"/>
<variable units="millivolt" public_interface="in" name="E_K"/>
<variable units="millivolt" public_interface="in" name="V"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>g_b_K</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>g_b_K_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_b_K_Periphery_Published</ci>
<ci>g_b_K_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>g_b_K_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_b_K_Periphery_0DCapable</ci>
<ci>g_b_K_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>g_b_K_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_b_K_Periphery_1DCapable</ci>
<ci>g_b_K_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>i_b_K</ci>
<apply>
<times/>
<ci>g_b_K</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="calcium_background_current">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="in" name="FCell"/>
<variable units="nanoA" public_interface="out" name="i_b_Ca"/>
<variable units="microS" name="g_b_Ca_Centre_Published" initial_value="1.32e-5"/>
<variable units="microS" name="g_b_Ca_Centre_0DCapable" initial_value="1.3236e-5"/>
<variable units="microS" name="g_b_Ca_Centre_1DCapable" initial_value="1.323e-5"/>
<variable units="microS" name="g_b_Ca_Periphery_Published" initial_value="4.3e-5"/>
<variable units="microS" name="g_b_Ca_Periphery_0DCapable" initial_value="4.2952e-5"/>
<variable units="microS" name="g_b_Ca_Periphery_1DCapable" initial_value="4.29e-5"/>
<variable units="microS" name="g_b_Ca"/>
<variable units="millivolt" public_interface="in" name="E_Ca"/>
<variable units="millivolt" public_interface="in" name="V"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>g_b_Ca</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>g_b_Ca_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_b_Ca_Periphery_Published</ci>
<ci>g_b_Ca_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>g_b_Ca_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_b_Ca_Periphery_0DCapable</ci>
<ci>g_b_Ca_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>g_b_Ca_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>g_b_Ca_Periphery_1DCapable</ci>
<ci>g_b_Ca_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>i_b_Ca</ci>
<apply>
<times/>
<ci>g_b_Ca</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_Ca</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="sodium_calcium_exchanger">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="in" name="FCell"/>
<variable units="nanoA" public_interface="out" name="i_NaCa"/>
<variable units="nanoA" name="k_NaCa_Centre_Published" initial_value="2.7e-6"/>
<variable units="nanoA" name="k_NaCa_Centre_0DCapable" initial_value="2.7229e-6"/>
<variable units="nanoA" name="k_NaCa_Centre_1DCapable" initial_value="2.8e-6"/>
<variable units="nanoA" name="k_NaCa_Periphery_Published" initial_value="8.8e-6"/>
<variable units="nanoA" name="k_NaCa_Periphery_0DCapable" initial_value="8.83584e-6"/>
<variable units="nanoA" name="k_NaCa_Periphery_1DCapable" initial_value="8.8e-6"/>
<variable units="nanoA" name="k_NaCa"/>
<variable units="dimensionless" name="d_NaCa" initial_value="0.0001"/>
<variable units="dimensionless" name="gamma_NaCa" initial_value="0.5"/>
<variable units="millimolar" public_interface="in" name="Na_i"/>
<variable units="millimolar" public_interface="in" name="Na_o"/>
<variable units="millimolar" public_interface="in" name="Ca_i"/>
<variable units="millimolar" public_interface="in" name="Ca_o"/>
<variable units="millivolt" public_interface="in" name="V"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>k_NaCa</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>k_NaCa_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>k_NaCa_Periphery_Published</ci>
<ci>k_NaCa_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>k_NaCa_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>k_NaCa_Periphery_0DCapable</ci>
<ci>k_NaCa_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>k_NaCa_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>k_NaCa_Periphery_1DCapable</ci>
<ci>k_NaCa_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>i_NaCa</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<times/>
<ci>k_NaCa</ci>
<apply>
<minus/>
<apply>
<times/>
<apply>
<power/>
<ci>Na_i</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<ci>Ca_o</ci>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.03743</cn>
<ci>V</ci>
<ci>gamma_NaCa</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<power/>
<ci>Na_o</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<ci>Ca_i</ci>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.0374</cn>
<ci>V</ci>
<apply>
<minus/>
<ci>gamma_NaCa</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="millimolar4">1</cn>
<apply>
<times/>
<ci>d_NaCa</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Ca_i</ci>
<apply>
<power/>
<ci>Na_o</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
</apply>
<apply>
<times/>
<ci>Ca_o</ci>
<apply>
<power/>
<ci>Na_i</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<times/>
<ci>k_NaCa</ci>
<apply>
<minus/>
<apply>
<times/>
<apply>
<power/>
<ci>Na_i</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<ci>Ca_o</ci>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.03743</cn>
<ci>V</ci>
<ci>gamma_NaCa</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<power/>
<ci>Na_o</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<ci>Ca_i</ci>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.03743</cn>
<ci>V</ci>
<apply>
<minus/>
<ci>gamma_NaCa</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="millimolar4">1</cn>
<apply>
<times/>
<ci>d_NaCa</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Ca_i</ci>
<apply>
<power/>
<ci>Na_o</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
</apply>
<apply>
<times/>
<ci>Ca_o</ci>
<apply>
<power/>
<ci>Na_i</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<component name="sodium_potassium_pump">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="in" name="FCell"/>
<variable units="nanoA" public_interface="out" name="i_p"/>
<variable units="millimolar" name="K_m_Na" initial_value="5.64"/>
<variable units="millimolar" name="K_m_K" initial_value="0.621"/>
<variable units="nanoA" name="i_p_max_Centre_Published" initial_value="0.0478"/>
<variable units="nanoA" name="i_p_max_Centre_0DCapable" initial_value="0.04782545"/>
<variable units="nanoA" name="i_p_max_Centre_1DCapable" initial_value="0.0478"/>
<variable units="nanoA" name="i_p_max_Periphery_Published" initial_value="0.16"/>
<variable units="nanoA" name="i_p_max_Periphery_0DCapable" initial_value="0.1551936"/>
<variable units="nanoA" name="i_p_max_Periphery_1DCapable" initial_value="0.16"/>
<variable units="nanoA" name="i_p_max"/>
<variable units="millimolar" public_interface="in" name="Na_i"/>
<variable units="millimolar" public_interface="in" name="K_o"/>
<variable units="millivolt" public_interface="in" name="V"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_p_max</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>i_p_max_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>i_p_max_Periphery_Published</ci>
<ci>i_p_max_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>i_p_max_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>i_p_max_Periphery_0DCapable</ci>
<ci>i_p_max_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>i_p_max_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>i_p_max_Periphery_1DCapable</ci>
<ci>i_p_max_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>i_p</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>i_p_max</ci>
<apply>
<power/>
<apply>
<divide/>
<ci>Na_i</ci>
<apply>
<plus/>
<ci>K_m_Na</ci>
<ci>Na_i</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">3</cn>
</apply>
<apply>
<power/>
<apply>
<divide/>
<ci>K_o</ci>
<apply>
<plus/>
<ci>K_m_K</ci>
<ci>K_o</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
<cn cellml:units="dimensionless">1.6</cn>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.5</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">60</cn>
</apply>
</apply>
<cn cellml:units="millivolt">40</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="persistent_calcium_current">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="dimensionless" public_interface="in" name="FCell"/>
<variable units="nanoA" public_interface="out" name="i_Ca_p"/>
<variable units="nanoA" name="i_Ca_p_max_Centre_Published" initial_value="0"/>
<variable units="nanoA" name="i_Ca_p_max_Centre_0DCapable" initial_value="0"/>
<variable units="nanoA" name="i_Ca_p_max_Centre_1DCapable" initial_value="0.0042"/>
<variable units="nanoA" name="i_Ca_p_max_Periphery_Published" initial_value="0"/>
<variable units="nanoA" name="i_Ca_p_max_Periphery_0DCapable" initial_value="0"/>
<variable units="nanoA" name="i_Ca_p_max_Periphery_1DCapable" initial_value="0.03339"/>
<variable units="nanoA" name="i_Ca_p_max"/>
<variable units="millimolar" public_interface="in" name="Ca_i"/>
<variable units="millivolt" public_interface="in" name="V"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_Ca_p_max</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>i_Ca_p_max_Centre_Published</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>i_Ca_p_max_Periphery_Published</ci>
<ci>i_Ca_p_max_Centre_Published</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>i_Ca_p_max_Centre_0DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>i_Ca_p_max_Periphery_0DCapable</ci>
<ci>i_Ca_p_max_Centre_0DCapable</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<ci>i_Ca_p_max_Centre_1DCapable</ci>
<apply>
<times/>
<ci>FCell</ci>
<apply>
<minus/>
<ci>i_Ca_p_max_Periphery_1DCapable</ci>
<ci>i_Ca_p_max_Centre_1DCapable</ci>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>i_Ca_p</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>i_Ca_p_max</ci>
<ci>Ca_i</ci>
</apply>
<apply>
<plus/>
<ci>Ca_i</ci>
<cn cellml:units="millimolar">0.0004</cn>
</apply>
</apply>
</apply>
</math>
</component>
<component name="ionic_concentrations">
<variable units="millimolar" public_interface="out" name="Na_i" initial_value="8"/>
<variable units="millimolar" public_interface="out" name="Na_o" initial_value="140"/>
<variable units="millimolar" public_interface="out" name="Ca_i" initial_value="0.0001"/>
<variable units="millimolar" public_interface="out" name="Ca_o" initial_value="2"/>
<variable units="millimolar" public_interface="out" name="K_i" initial_value="140"/>
<variable units="millimolar" public_interface="out" name="K_o" initial_value="5.4"/>
</component>
<component name="reversal_and_equilibrium_potentials">
<variable units="dimensionless" public_interface="in" name="Version"/>
<variable units="millivolt" public_interface="out" name="E_Na"/>
<variable units="millivolt" public_interface="out" name="E_K"/>
<variable units="millivolt" public_interface="out" name="E_K_s"/>
<variable units="millivolt" public_interface="out" name="E_Ca"/>
<variable units="millimolar" public_interface="in" name="K_o"/>
<variable units="millimolar" public_interface="in" name="Na_o"/>
<variable units="millimolar" public_interface="in" name="K_i"/>
<variable units="millimolar" public_interface="in" name="Na_i"/>
<variable units="millimolar" public_interface="in" name="Ca_o"/>
<variable units="millimolar" public_interface="in" name="Ca_i"/>
<variable units="millijoule_per_mole_kelvin" public_interface="in" name="R"/>
<variable units="coulomb_per_mole" public_interface="in" name="F"/>
<variable units="kelvin" public_interface="in" name="T"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>E_Na</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<ci>F</ci>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>Na_o</ci>
<ci>Na_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E_K</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<ci>F</ci>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>K_o</ci>
<ci>K_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E_Ca</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>F</ci>
</apply>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>Ca_o</ci>
<ci>Ca_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E_K_s</ci>
<piecewise>
<piece>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<ci>F</ci>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<apply>
<plus/>
<ci>K_o</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.12</cn>
<ci>Na_o</ci>
</apply>
</apply>
<apply>
<plus/>
<ci>K_i</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.12</cn>
<ci>Na_i</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Version</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<otherwise>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<ci>F</ci>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<apply>
<plus/>
<ci>K_o</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.03</cn>
<ci>Na_o</ci>
</apply>
</apply>
<apply>
<plus/>
<ci>K_i</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.03</cn>
<ci>Na_i</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<group>
<relationship_ref relationship="containment"/>
<component_ref component="membrane">
<component_ref component="sodium_current">
<component_ref component="sodium_current_m_gate"/>
<component_ref component="sodium_current_h_gate"/>
</component_ref>
<component_ref component="L_type_Ca_channel">
<component_ref component="L_type_Ca_channel_d_gate"/>
<component_ref component="L_type_Ca_channel_f_gate"/>
</component_ref>
<component_ref component="T_type_Ca_channel">
<component_ref component="T_type_Ca_channel_d_gate"/>
<component_ref component="T_type_Ca_channel_f_gate"/>
</component_ref>
<component_ref component="four_AP_sensitive_currents">
<component_ref component="four_AP_sensitive_currents_q_gate"/>
<component_ref component="four_AP_sensitive_currents_r_gate"/>
</component_ref>
<component_ref component="rapid_delayed_rectifying_potassium_current">
<component_ref component="rapid_delayed_rectifying_potassium_current_P_af_gate"/>
<component_ref component="rapid_delayed_rectifying_potassium_current_P_as_gate"/>
<component_ref component="rapid_delayed_rectifying_potassium_current_P_i_gate"/>
</component_ref>
<component_ref component="slow_delayed_rectifying_potassium_current">
<component_ref component="slow_delayed_rectifying_potassium_current_xs_gate"/>
</component_ref>
<component_ref component="hyperpolarisation_activated_current">
<component_ref component="hyperpolarisation_activated_current_y_gate"/>
</component_ref>
<component_ref component="sodium_background_current"/>
<component_ref component="calcium_background_current"/>
<component_ref component="potassium_background_current"/>
<component_ref component="sodium_calcium_exchanger"/>
<component_ref component="sodium_potassium_pump"/>
<component_ref component="persistent_calcium_current"/>
<component_ref component="ionic_concentrations"/>
<component_ref component="reversal_and_equilibrium_potentials"/>
</component_ref>
</group>
<group>
<relationship_ref relationship="encapsulation"/>
<component_ref component="sodium_current">
<component_ref component="sodium_current_m_gate"/>
<component_ref component="sodium_current_h_gate"/>
</component_ref>
<component_ref component="L_type_Ca_channel">
<component_ref component="L_type_Ca_channel_d_gate"/>
<component_ref component="L_type_Ca_channel_f_gate"/>
</component_ref>
<component_ref component="T_type_Ca_channel">
<component_ref component="T_type_Ca_channel_d_gate"/>
<component_ref component="T_type_Ca_channel_f_gate"/>
</component_ref>
<component_ref component="four_AP_sensitive_currents">
<component_ref component="four_AP_sensitive_currents_q_gate"/>
<component_ref component="four_AP_sensitive_currents_r_gate"/>
</component_ref>
<component_ref component="rapid_delayed_rectifying_potassium_current">
<component_ref component="rapid_delayed_rectifying_potassium_current_P_af_gate"/>
<component_ref component="rapid_delayed_rectifying_potassium_current_P_as_gate"/>
<component_ref component="rapid_delayed_rectifying_potassium_current_P_i_gate"/>
</component_ref>
<component_ref component="slow_delayed_rectifying_potassium_current">
<component_ref component="slow_delayed_rectifying_potassium_current_xs_gate"/>
</component_ref>
<component_ref component="hyperpolarisation_activated_current">
<component_ref component="hyperpolarisation_activated_current_y_gate"/>
</component_ref>
</group>
<connection>
<map_components component_2="environment" component_1="membrane"/>
<map_variables variable_2="time" variable_1="time"/>
</connection>
<connection>
<map_components component_2="environment" component_1="sodium_current"/>
<map_variables variable_2="time" variable_1="time"/>
</connection>
<connection>
<map_components component_2="environment" component_1="L_type_Ca_channel"/>
<map_variables variable_2="time" variable_1="time"/>
</connection>
<connection>
<map_components component_2="environment" component_1="T_type_Ca_channel"/>
<map_variables variable_2="time" variable_1="time"/>
</connection>
<connection>
<map_components component_2="environment" component_1="four_AP_sensitive_currents"/>
<map_variables variable_2="time" variable_1="time"/>
</connection>
<connection>
<map_components component_2="environment" component_1="rapid_delayed_rectifying_potassium_current"/>
<map_variables variable_2="time" variable_1="time"/>
</connection>
<connection>
<map_components component_2="environment" component_1="slow_delayed_rectifying_potassium_current"/>
<map_variables variable_2="time" variable_1="time"/>
</connection>
<connection>
<map_components component_2="environment" component_1="hyperpolarisation_activated_current"/>
<map_variables variable_2="time" variable_1="time"/>
</connection>
<connection>
<map_components component_2="sodium_current" component_1="membrane"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="i_Na" variable_1="i_Na"/>
<map_variables variable_2="V" variable_1="V"/>
<map_variables variable_2="R" variable_1="R"/>
<map_variables variable_2="T" variable_1="T"/>
<map_variables variable_2="F" variable_1="F"/>
</connection>
<connection>
<map_components component_2="L_type_Ca_channel" component_1="membrane"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="i_Ca_L" variable_1="i_Ca_L"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="T_type_Ca_channel" component_1="membrane"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="i_Ca_T" variable_1="i_Ca_T"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="four_AP_sensitive_currents" component_1="membrane"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="i_to" variable_1="i_to"/>
<map_variables variable_2="i_sus" variable_1="i_sus"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="rapid_delayed_rectifying_potassium_current" component_1="membrane"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="i_K_r" variable_1="i_K_r"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="slow_delayed_rectifying_potassium_current" component_1="membrane"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="i_K_s" variable_1="i_K_s"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="hyperpolarisation_activated_current" component_1="membrane"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="i_f_Na" variable_1="i_f_Na"/>
<map_variables variable_2="i_f_K" variable_1="i_f_K"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="sodium_background_current" component_1="membrane"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="V" variable_1="V"/>
<map_variables variable_2="i_b_Na" variable_1="i_b_Na"/>
</connection>
<connection>
<map_components component_2="potassium_background_current" component_1="membrane"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="V" variable_1="V"/>
<map_variables variable_2="i_b_K" variable_1="i_b_K"/>
</connection>
<connection>
<map_components component_2="calcium_background_current" component_1="membrane"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="V" variable_1="V"/>
<map_variables variable_2="i_b_Ca" variable_1="i_b_Ca"/>
</connection>
<connection>
<map_components component_2="sodium_calcium_exchanger" component_1="membrane"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="i_NaCa" variable_1="i_NaCa"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="sodium_potassium_pump" component_1="membrane"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="i_p" variable_1="i_p"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="persistent_calcium_current" component_1="membrane"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="i_Ca_p" variable_1="i_Ca_p"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="reversal_and_equilibrium_potentials" component_1="membrane"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="R" variable_1="R"/>
<map_variables variable_2="T" variable_1="T"/>
<map_variables variable_2="F" variable_1="F"/>
</connection>
<connection>
<map_components component_2="sodium_current" component_1="reversal_and_equilibrium_potentials"/>
<map_variables variable_2="E_Na" variable_1="E_Na"/>
</connection>
<connection>
<map_components component_2="sodium_current" component_1="ionic_concentrations"/>
<map_variables variable_2="Na_o" variable_1="Na_o"/>
</connection>
<connection>
<map_components component_2="four_AP_sensitive_currents" component_1="reversal_and_equilibrium_potentials"/>
<map_variables variable_2="E_K" variable_1="E_K"/>
</connection>
<connection>
<map_components component_2="rapid_delayed_rectifying_potassium_current" component_1="reversal_and_equilibrium_potentials"/>
<map_variables variable_2="E_K" variable_1="E_K"/>
</connection>
<connection>
<map_components component_2="slow_delayed_rectifying_potassium_current" component_1="reversal_and_equilibrium_potentials"/>
<map_variables variable_2="E_K_s" variable_1="E_K_s"/>
</connection>
<connection>
<map_components component_2="hyperpolarisation_activated_current" component_1="reversal_and_equilibrium_potentials"/>
<map_variables variable_2="E_K" variable_1="E_K"/>
<map_variables variable_2="E_Na" variable_1="E_Na"/>
</connection>
<connection>
<map_components component_2="sodium_background_current" component_1="reversal_and_equilibrium_potentials"/>
<map_variables variable_2="E_Na" variable_1="E_Na"/>
</connection>
<connection>
<map_components component_2="potassium_background_current" component_1="reversal_and_equilibrium_potentials"/>
<map_variables variable_2="E_K" variable_1="E_K"/>
</connection>
<connection>
<map_components component_2="calcium_background_current" component_1="reversal_and_equilibrium_potentials"/>
<map_variables variable_2="E_Ca" variable_1="E_Ca"/>
</connection>
<connection>
<map_components component_2="ionic_concentrations" component_1="sodium_calcium_exchanger"/>
<map_variables variable_2="Ca_i" variable_1="Ca_i"/>
<map_variables variable_2="Na_i" variable_1="Na_i"/>
<map_variables variable_2="Ca_o" variable_1="Ca_o"/>
<map_variables variable_2="Na_o" variable_1="Na_o"/>
</connection>
<connection>
<map_components component_2="ionic_concentrations" component_1="sodium_potassium_pump"/>
<map_variables variable_2="Na_i" variable_1="Na_i"/>
<map_variables variable_2="K_o" variable_1="K_o"/>
</connection>
<connection>
<map_components component_2="ionic_concentrations" component_1="reversal_and_equilibrium_potentials"/>
<map_variables variable_2="K_o" variable_1="K_o"/>
<map_variables variable_2="Na_o" variable_1="Na_o"/>
<map_variables variable_2="K_i" variable_1="K_i"/>
<map_variables variable_2="Na_i" variable_1="Na_i"/>
<map_variables variable_2="Ca_o" variable_1="Ca_o"/>
<map_variables variable_2="Ca_i" variable_1="Ca_i"/>
</connection>
<connection>
<map_components component_2="ionic_concentrations" component_1="persistent_calcium_current"/>
<map_variables variable_2="Ca_i" variable_1="Ca_i"/>
</connection>
<connection>
<map_components component_2="sodium_current_m_gate" component_1="sodium_current"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="m" variable_1="m"/>
<map_variables variable_2="time" variable_1="time"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="sodium_current_h_gate" component_1="sodium_current"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="h" variable_1="h"/>
<map_variables variable_2="time" variable_1="time"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="L_type_Ca_channel_d_gate" component_1="L_type_Ca_channel"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="d_L" variable_1="d_L"/>
<map_variables variable_2="time" variable_1="time"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="L_type_Ca_channel_f_gate" component_1="L_type_Ca_channel"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="f_L" variable_1="f_L"/>
<map_variables variable_2="time" variable_1="time"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="T_type_Ca_channel_d_gate" component_1="T_type_Ca_channel"/>
<map_variables variable_2="d_T" variable_1="d_T"/>
<map_variables variable_2="time" variable_1="time"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="T_type_Ca_channel_f_gate" component_1="T_type_Ca_channel"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="f_T" variable_1="f_T"/>
<map_variables variable_2="time" variable_1="time"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="four_AP_sensitive_currents_q_gate" component_1="four_AP_sensitive_currents"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="FCell" variable_1="FCell"/>
<map_variables variable_2="q" variable_1="q"/>
<map_variables variable_2="time" variable_1="time"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="four_AP_sensitive_currents_r_gate" component_1="four_AP_sensitive_currents"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="r" variable_1="r"/>
<map_variables variable_2="time" variable_1="time"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="rapid_delayed_rectifying_potassium_current_P_af_gate" component_1="rapid_delayed_rectifying_potassium_current"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="P_af" variable_1="P_af"/>
<map_variables variable_2="time" variable_1="time"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="rapid_delayed_rectifying_potassium_current_P_as_gate" component_1="rapid_delayed_rectifying_potassium_current"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="P_as" variable_1="P_as"/>
<map_variables variable_2="time" variable_1="time"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="rapid_delayed_rectifying_potassium_current_P_as_gate" component_1="rapid_delayed_rectifying_potassium_current_P_af_gate"/>
<map_variables variable_2="P_af_infinity" variable_1="P_af_infinity"/>
</connection>
<connection>
<map_components component_2="rapid_delayed_rectifying_potassium_current_P_i_gate" component_1="rapid_delayed_rectifying_potassium_current"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="P_i" variable_1="P_i"/>
<map_variables variable_2="time" variable_1="time"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="slow_delayed_rectifying_potassium_current_xs_gate" component_1="slow_delayed_rectifying_potassium_current"/>
<map_variables variable_2="xs" variable_1="xs"/>
<map_variables variable_2="time" variable_1="time"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<connection>
<map_components component_2="hyperpolarisation_activated_current_y_gate" component_1="hyperpolarisation_activated_current"/>
<map_variables variable_2="Version" variable_1="Version"/>
<map_variables variable_2="y" variable_1="y"/>
<map_variables variable_2="time" variable_1="time"/>
<map_variables variable_2="V" variable_1="V"/>
</connection>
<rdf:RDF>
<rdf:Seq rdf:about="rdf:#764ddda8-7616-491d-bcaf-6dcafbb4fd9e">
<rdf:li rdf:resource="rdf:#3d5b2d2f-21cb-4ab0-89dc-4d7b1d7fae37"/>
<rdf:li rdf:resource="rdf:#1f8592f9-ddf1-4658-b620-9ccfde24489f"/>
<rdf:li rdf:resource="rdf:#9b3771be-eec7-45b2-b933-501781adcba0"/>
<rdf:li rdf:resource="rdf:#3f20fcf6-f78c-4b03-952c-ba82eaa9f18f"/>
<rdf:li rdf:resource="rdf:#13e39802-b6f3-4a19-98b0-7c262828f860"/>
</rdf:Seq>
<rdf:Seq rdf:about="rdf:#3364787b-b2b6-4138-97fb-28184ae9c975"/>
<rdf:Description rdf:about="rdf:#82cf3613-cdd1-463c-a65c-0944876be2f2">
<bqs:Pubmed_id>14760914</bqs:Pubmed_id>
<bqs:JournalArticle rdf:resource="rdf:#81707d62-bec9-403b-8f84-1f384c89d36c"/>
</rdf:Description>
<rdf:Description rdf:about="">
<dc:publisher/>
<cmeta:comment rdf:resource="rdf:#91c39199-534a-4e90-be53-69bb3a63e4e8"/>
<dcterms:created rdf:resource="rdf:#b12d9f8e-f48c-4f42-9eef-fc7e63fef60c"/>
<dc:creator rdf:resource="rdf:#7e38bbff-ac04-45ce-b64f-2ee49ec37ecd"/>
<cmeta:modification rdf:resource="rdf:#24b01c2a-8286-440d-9a5f-5c4b42782eb7"/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#5b071acc-6e39-41a5-9fd5-737c5f63d600">
<vCard:Orgname>University of Oxford</vCard:Orgname>
<vCard:Orgunit/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#bdbc1b2f-ca5e-4503-9aea-b1a4b43c0a36">
<vCard:Given>Peter</vCard:Given>
<vCard:Family>Hunter</vCard:Family>
</rdf:Description>
<rdf:Description rdf:about="rdf:#3e106ba6-bd5d-4464-909c-c72a8b0c2694">
<vCard:Given>Alan</vCard:Given>
<vCard:Family>Garny</vCard:Family>
<vCard:Other/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#3059b3f3-49ba-4f6a-9125-cf9ddf278973">
<vCard:Given>Peter</vCard:Given>
<vCard:Family>Kohl</vCard:Family>
</rdf:Description>
<rdf:Description rdf:about="rdf:#7148062f-ed2d-43ae-908e-c106584970f5">
<dc:creator rdf:resource="rdf:#52621f6a-3b7c-4780-8347-1eb95a94340b"/>
<rdf:value/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#ef2b65bc-da26-4673-8c8b-aef11452999c">
<dc:creator rdf:resource="rdf:#3364787b-b2b6-4138-97fb-28184ae9c975"/>
<dc:title/>
<bqs:volume/>
<bqs:first_page/>
<bqs:Journal rdf:resource="rdf:#05290d8f-605c-4c67-bace-0b5a85f3f229"/>
<dcterms:issued rdf:resource="rdf:#12d6d63a-3b64-4f4d-9768-292d021b9551"/>
<bqs:last_page/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#12d6d63a-3b64-4f4d-9768-292d021b9551">
<dcterms:W3CDTF/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#3d5b2d2f-21cb-4ab0-89dc-4d7b1d7fae37">
<rdf:type rdf:resource="http://www.cellml.org/bqs/1.0#Person"/>
<vCard:N rdf:resource="rdf:#8c6316d7-cc35-4ef8-8300-6ad2addffdfc"/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#91c39199-534a-4e90-be53-69bb3a63e4e8">
<dc:creator rdf:resource="rdf:#8076ddb1-c6a9-4a4f-b185-91bcc97f678e"/>
<rdf:value>This version of the CellML model was created by Alan Garny of Oxford University, it has been unit checked and the model runs in both COR and PCEnv to reproduce the published results.</rdf:value>
</rdf:Description>
<rdf:Description rdf:about="rdf:#8c6316d7-cc35-4ef8-8300-6ad2addffdfc">
<vCard:Given>Alan</vCard:Given>
<vCard:Family>Garny</vCard:Family>
</rdf:Description>
<rdf:Description rdf:about="rdf:#1f8592f9-ddf1-4658-b620-9ccfde24489f">
<rdf:type rdf:resource="http://www.cellml.org/bqs/1.0#Person"/>
<vCard:N rdf:resource="rdf:#3059b3f3-49ba-4f6a-9125-cf9ddf278973"/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#f6bcb714-aba0-467b-885b-1aaec131d502">
<vCard:Given>Mark</vCard:Given>
<vCard:Family>Boyett</vCard:Family>
</rdf:Description>
<rdf:Description rdf:about="rdf:#9b3771be-eec7-45b2-b933-501781adcba0">
<rdf:type rdf:resource="http://www.cellml.org/bqs/1.0#Person"/>
<vCard:N rdf:resource="rdf:#bdbc1b2f-ca5e-4503-9aea-b1a4b43c0a36"/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#52621f6a-3b7c-4780-8347-1eb95a94340b">
<vCard:FN/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#24b01c2a-8286-440d-9a5f-5c4b42782eb7">
<dcterms:modified rdf:resource="rdf:#8ee843f2-bcee-4c88-920a-3b3988ca4470"/>
<rdf:value>Fixed the CellML model such that it now runs to recreate the published results... Alan is himself the author of the original publication so there was no need to collaborate with anyone else!</rdf:value>
<cmeta:modifier rdf:resource="rdf:#55a43666-507c-450c-9fee-523fd43e2cf0"/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#05290d8f-605c-4c67-bace-0b5a85f3f229">
<dc:title/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#9fe41fa9-6887-4de4-84d6-51b262d2e2d2">
<dc:title>Journal of Cardiovascular Electrophysiology</dc:title>
</rdf:Description>
<rdf:Description rdf:about="rdf:#3f20fcf6-f78c-4b03-952c-ba82eaa9f18f">
<rdf:type rdf:resource="http://www.cellml.org/bqs/1.0#Person"/>
<vCard:N rdf:resource="rdf:#f6bcb714-aba0-467b-885b-1aaec131d502"/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#8ee843f2-bcee-4c88-920a-3b3988ca4470">
<dcterms:W3CDTF>2008-04-30T02:53:02+12:00</dcterms:W3CDTF>
</rdf:Description>
<rdf:Description rdf:about="rdf:#6568ae9b-a2c9-425a-84f5-45d5a059b954">
<bqs:Pubmed_id/>
<bqs:JournalArticle rdf:resource="rdf:#ef2b65bc-da26-4673-8c8b-aef11452999c"/>
</rdf:Description>
<rdf:Description rdf:about="#garny_2003">
<bqs:reference rdf:resource="rdf:#6568ae9b-a2c9-425a-84f5-45d5a059b954"/>
<bqs:reference rdf:resource="rdf:#82cf3613-cdd1-463c-a65c-0944876be2f2"/>
<cmeta:comment rdf:resource="rdf:#7148062f-ed2d-43ae-908e-c106584970f5"/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#55a43666-507c-450c-9fee-523fd43e2cf0">
<vCard:N rdf:resource="rdf:#3e106ba6-bd5d-4464-909c-c72a8b0c2694"/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#03c0994c-37a7-40da-8275-c13e4114a0e9">
<dcterms:W3CDTF>2003-10-00 00:00</dcterms:W3CDTF>
</rdf:Description>
<rdf:Description rdf:about="rdf:#b12d9f8e-f48c-4f42-9eef-fc7e63fef60c">
<dcterms:W3CDTF>2008-04-30T00:00:00+00:00</dcterms:W3CDTF>
</rdf:Description>
<rdf:Description rdf:about="rdf:#13e39802-b6f3-4a19-98b0-7c262828f860">
<rdf:type rdf:resource="http://www.cellml.org/bqs/1.0#Person"/>
<vCard:N rdf:resource="rdf:#594f7ad1-60f1-4ec6-9191-0a40b1561664"/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#81707d62-bec9-403b-8f84-1f384c89d36c">
<dc:creator rdf:resource="rdf:#764ddda8-7616-491d-bcaf-6dcafbb4fd9e"/>
<dc:title>One-dimensional rabbit sinoatrial node models: benefits and limitations</dc:title>
<bqs:volume>14</bqs:volume>
<bqs:first_page>S121</bqs:first_page>
<bqs:Journal rdf:resource="rdf:#9fe41fa9-6887-4de4-84d6-51b262d2e2d2"/>
<dcterms:issued rdf:resource="rdf:#03c0994c-37a7-40da-8275-c13e4114a0e9"/>
<bqs:last_page>S132</bqs:last_page>
</rdf:Description>
<rdf:Description rdf:about="rdf:#7e38bbff-ac04-45ce-b64f-2ee49ec37ecd">
<vCard:ORG rdf:resource="rdf:#5b071acc-6e39-41a5-9fd5-737c5f63d600"/>
<vCard:EMAIL rdf:resource="rdf:#1857aadc-0a49-4b6c-805f-cdbea7593a0e"/>
<vCard:N rdf:resource="rdf:#1425910d-02a8-4760-9484-cd357f37f28c"/>
</rdf:Description>
<rdf:Description rdf:about="rdf:#8076ddb1-c6a9-4a4f-b185-91bcc97f678e">
<vCard:FN>Catherine Lloyd</vCard:FN>
</rdf:Description>
<rdf:Description rdf:about="rdf:#1857aadc-0a49-4b6c-805f-cdbea7593a0e">
<rdf:type rdf:resource="http://imc.org/vCard/3.0#internet"/>
<rdf:value>alan.garny@dpag.ox.ac.uk</rdf:value>
</rdf:Description>
<rdf:Description rdf:about="rdf:#594f7ad1-60f1-4ec6-9191-0a40b1561664">
<vCard:Given>Denis</vCard:Given>
<vCard:Family>Noble</vCard:Family>
</rdf:Description>
<rdf:Description rdf:about="rdf:#1425910d-02a8-4760-9484-cd357f37f28c">
<vCard:Given>Alan</vCard:Given>
<vCard:Family>Garny</vCard:Family>
<vCard:Other/>
</rdf:Description>
</rdf:RDF>
</model>
