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Model Mathematics

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Component: environment

Component: Ca_m

\frac{d}{d time} (Ca_m) = J_min - J_mout

Component: J_min

J_min = \frac{k_min {Ca_cyt}^{n}}{{K_m}^{n} + {Ca_cyt}^{n}}

Component: J_mout

J_mout = \frac{k_mout Ca_m}{1}

Component: Ca_cyt

\frac{d}{d time} (Ca_cyt) = (((J_ERch - J_ERpump) + J_ERleak + J_in - J_out) + J_mout - J_min) 1

Component: Ca_ER

\frac{d}{d time} (Ca_ER) = (J_ERpump - J_ERleak - J_ERch) 1

Component: J_ERch

\frac{d}{d time} (J_ERch) = beta k_0ch \frac{{Ca_cyt}^{4}}{{K_chcyt}^{4} + {Ca_cyt}^{4}} \frac{{Ca_ER}^{2}}{{K_chER}^{2} + {Ca_ER}^{2}} 1

Component: J_ERpump

\frac{d}{d time} (J_ERpump) = K_ERpump \frac{{Ca_cyt}^{2}}{{K_pump}^{2} + {Ca_cyt}^{2}}

Component: J_ERleak

\frac{d}{d time} (J_ERleak) = \frac{K_ERleak Ca_ER}{1} 1

Component: J_in

\frac{d}{d time} (J_in) = K_0in 1

Component: J_out

\frac{d}{d time} (J_out) = \frac{K_out Ca_cyt}{1} 1

Source: Derived from workspace Mitochondria regulate the amplitude of simple and complex calcium oscillations at changeset f78690e2f464.

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