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A Simple Voltage-Modulated Markov Chain Model for the Piezo1 Ion Channel to Investigate Electromechanical Pacing
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ogiermann_2025_piezo1.cellml
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Model Mathematics
Component based math viewer is available
Component: kinetics
r2
=
r1
r3
r5
r4
r6
ce2
=
ce1
+
ce3
+
ce5
-
ce4
-
ce6
cm2
=
-
cm4
p_O_I1
=
r1
ⅇ
ce1
gradmu
140
p_I1_O
=
r2
ⅇ
ce2
gradmu
140
+
cm2
pressure
70
p_I1_C
=
r3
ⅇ
ce3
gradmu
140
p_C_I1
=
r4
ⅇ
ce4
gradmu
140
+
cm4
pressure
70
p_C_O
=
r5
ⅇ
ce5
gradmu
140
p_O_C
=
r6
ⅇ
ce6
gradmu
140
p_I2_O
=
r7
ⅇ
ce7
gradmu
140
pressure
70
p_O_I2
=
r8
ⅇ
ce8
gradmu
140
d
d
time
P_Open
=
-
p_O_I1
+
p_O_I2
+
p_O_C
P_Open
+
p_C_O
P_Closed
+
p_I1_O
P_I1
+
p_I2_O
P_I2
d
d
time
P_Closed
=
-
p_C_I1
+
p_C_O
P_Closed
+
p_O_C
P_Open
+
p_I1_C
P_I1
d
d
time
P_I1
=
-
p_I1_O
+
p_I1_C
P_I1
+
p_C_I1
P_Closed
+
p_O_I1
P_Open
d
d
time
P_I2
=
-
p_I2_O
P_I2
+
p_O_I2
P_Open
Component: parameters
r2
=
r1
r3
r5
r4
r6
ce2
=
ce1
+
ce3
+
ce5
-
ce4
-
ce6
cm2
=
-
cm4
Component: equilibrium
Source
Derived from workspace
A Simple Voltage-Modulated Markov Chain Model for the Piezo1 Ion Channel to Investigate Electromechanical Pacing
at changeset
8465ce0a385c
.
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ogiermann_2025_piezo1.cellml