You are here: Home / Exposures / Gupta, Aslakson, Gurbaxani, Vernon, 2007 / Inclusion of the glucocorticoid receptor in a hypothalamic pituitary adrenal axis model reveals bistability

Model Mathematics

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Component: environment

Component: c

\frac{d}{d time} (c) = \frac{1.0 + f}{1.0 + \frac{o}{ki1}} - (kcd c) f = \{\begin{matrix} 1.0 if time > 0.0 \land time < 2.0 \lor time > 8.0 \land time < 10.0 \lor time > 16.0 \land time < 18.0 \\ 0.0 otherwise \end{matrix}

Component: a

\frac{d}{d time} (a) = \frac{c}{1.0 + \frac{o r}{ki2}} - (kad a)

Component: r

\frac{d}{d time} (r) = \frac{{(o r)}^{2.0}}{k + {(o r)}^{2.0}} + kcr - (krd r)

Component: o

\frac{d}{d time} (o) = a - o

Component: reaction_constants

Source: Derived from workspace Gupta, Aslakson, Gurbaxani, Vernon, 2007 at changeset 7b5697c550fa.; This exposure was expired. A more up-to-date exposure is available, or view related resources.

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