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Model Mathematics

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Component: environment

Component: kinetic_parameters

Component: S

\frac{d}{d time} (S) = a - (b S + c S V)

Component: I1

\frac{d}{d time} (I1) = c S V - (k I1)

Component: I2

\frac{d}{d time} (I2) = k (I1 - I2)

Component: I3

\frac{d}{d time} (I3) = k (I2 - I3)

Component: I4

\frac{d}{d time} (I4) = k (I3 - I4)

Component: I5

\frac{d}{d time} (I5) = k (I4 - I5)

Component: V

\frac{d}{d time} (V) = p I5 - (q V)

Component: Se

Se = \frac{q k}{p c}

Component: Ve

Ve = \frac{b}{c} (R0 - 1.0) R0 = \frac{a p c}{b q k}

Component: I1e

I1e = \frac{q}{p} Ve

Component: I2e

I2e = \frac{q}{p} Ve

Component: I3e

I3e = \frac{q}{p} Ve

Component: I4e

I4e = \frac{q}{p} Ve

Component: I5e

I5e = \frac{q}{p} Ve

Source: Derived from workspace Grossman, Feinberg, Kuznetsov, Dimitrov, Paul, 1998 at changeset 1675893a43b0.

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HIV infection: how effective is drug combination treatment?