Model Mathematics

Component: environment

Component: parameters

F_vol=1e12111000FC_vol

Component: O_stim

H_0=0iftime<t_01otherwise H_1=0iftime<t_11otherwise O_stim=odH_0-H_1

Component: bLR

ddtimebLR=k_1O_stimR_tot-bLR-r_1bLR

Component: aG

ddtimeaG=k_GG_tot-aG-r_G

Component: k_G

k_G=k_2bLR

Component: r_G

r_G=r_2aG

Component: cAMP

ddtimecAMP=synth-degrad

Component: synth

synth=aGsmax1+aCaMKkinhninh

Component: degrad

degrad=pdcAMP

Component: Ca

ddtimeCa=10001infI_CNG-J_NCX-cc_1-cc_2CaCaM

Component: cc_1

cc_1=cc1linCa

Component: CaCaM

ddtimeCaCaM=cc_1-cc_2CaCaM

Component: aCaMK

ddtimeaCaMK=ck_1-ck_2aCaMK

Component: ck_1

ck_1=ck1linCaCaM

Component: V

ddtimeV=100011capI_CNG+I_ClCa+I_NCX+I_other

Component: I_CNG

I_CNG=cnmaxcAMPn_1cAMPn_1+inhcnghmc_1n_111000V_cng-V

Component: inhcng

inhcng=1+inhmax-1CaCaMninhcngCaCaMninhcng+kinhcngninhcng

Component: I_ClCa

I_ClCa=clmaxCan_2Can_2+hmc_2n_211000V_Cl-V

Component: I_NCX

I_NCX=11000F_volJ_NCX

Component: J_NCX

J_NCX=efCa

Component: I_other

I_other=gl11000V_l-V