You are here: Home / Exposures / Nagerl, Novo, Mody, Vergara, 2000 / Binding Kinetics of Calbindin-D28k Determined by Flash Photolysis of Caged Ca2+

Model Mathematics

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Component: environment

Component: Ca

Ca = Ca_T - (CaD + CaDM1 + CaDM2 + CaBi)

Component: DM_T

Component: DM1

DM1 = DM_T alpha - CaDM1

Component: DM1_T

DM1_T = DM1 + CaDM1

Component: DM2

DM2 = DM_T (1.0 - alpha) - CaDM2

Component: DM2_T

DM2_T = DM2 + CaDM2

Component: D

D = D_T - CaD

Component: Bi

Bi_T = Bi + CaBi

Component: CaDM1

\frac{d}{d time} (CaDM1) = \{\begin{matrix} kon_DM Ca DM1 - (koff_DM CaDM1) if t_pulse = 0.0 \\ kon_DM Ca DM1 - (k_trans CaDM1) otherwise \end{matrix}

Component: CaDM2

\frac{d}{d time} (CaDM2) = kon_DM Ca DM2 - (koff_DM CaDM2)

Component: CaD

\frac{d}{d time} (CaD) = kon_D Ca D - (koff_D CaD)

Component: CaBi

\frac{d}{d time} (CaBi) = kon_Bi Ca Bi - (koff_Bi CaBi)

Component: constants

k_trans = koff_DM + (koff_DM_- koff_DM) (1.0 - (ⅇ^{\frac{- (time - t_pulse)}{tau_photolysis}}))

Source: Derived from workspace Nagerl, Novo, Mody, Vergara, 2000 at changeset 05fdb97bfb80.

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Binding Kinetics of Calbindin-D28k Determined by Flash Photolysis of Caged Ca2+