You are here: Home / Exposures / Saftenku, Williams, Sitsapesan, 2001 / Markovian Models of Low and High Activity Levals of Cardiac Ryanodine Receptors (H1 Model)

Model Mathematics

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Component: environment

Component: C1

\frac{d}{d time} (C1) = C2C1 C2 - (C1C2 Ca C2)

Component: C2

\frac{d}{d time} (C2) = C1C2 C1 Ca + C3C2 C3 + O1C2 O1 - (C2C1 C2 + C2C3 Ca C2 + C2O1 Ca O1)

Component: C3

\frac{d}{d time} (C3) = O2C3 O2 + C2C3 Ca C2 - (C3O2 Ca C3 + C3C2 C3)

Component: C4

\frac{d}{d time} (C4) = O2C4 O2 - (C4O2 C4)

Component: O1

\frac{d}{d time} (O1) = C2O1 C2 Ca - (O1C2 O1)

Component: O2

\frac{d}{d time} (O2) = C3O2 Ca C3 + C4O2 C4 - (O2C3 O2 + O2C4 O2)

Component: reaction_constants

Source: Derived from workspace Saftenku, Williams, Sitsapesan, 2001 at changeset 1cbe5b18da91.

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