Model Mathematics

Component based math viewer is available

Component: environment

Component: BMK1

\frac{d}{d time} (BMK1) = v10b - v10a

Component: MRNA

\frac{d}{d time} (MRNA) = v19 - v18

Component: NFATc

\frac{d}{d time} (NFATc) = v14 - (v1 + v15)

Component: NFATn

\frac{d}{d time} (NFATn) = v1 + v16 - (v17 + v18)

Component: NFATpc

\frac{d}{d time} (NFATpc) = v2 + v15 - (v9 + v14)

Component: NFATpn

\frac{d}{d time} (NFATpn) = v17 - (v2 + v16)

Component: GSK3betac

\frac{d}{d time} (GSK3betac) = v12b + v15b - (v3 + v12a + v15a)

Component: GSK3betan

\frac{d}{d time} (GSK3betan) = v3 + v17b - v17a

Component: CaNc

\frac{d}{d time} (CaNc) = - v6

Component: CaNc_star

\frac{d}{d time} (CaNc_star) = v6 + v11b + v13b + v14b - (v4 + v7 + v11a + v13a + v14a)

Component: CaNn_star

\frac{d}{d time} (CaNn_star) = v4 + v16b - v16a

Component: CaNn

\frac{d}{d time} (CaNn) = - v6

Component: CaM

\frac{d}{d time} (CaM) = - v5

Component: CaMCa

\frac{d}{d time} (CaMCa) = v5 - v6

Component: MCIP

\frac{d}{d time} (MCIP) = v11 - (v7 + v10 + v19)

Component: MCIPp

\frac{d}{d time} (MCIPp) = v10 + v13 - (v11 + v12)

Component: MCIPpp

\frac{d}{d time} (MCIPpp) = v12 - (v8 + v13)

Component: Comp1

\frac{d}{d time} (Comp1) = v7

Component: Comp2

\frac{d}{d time} (Comp2) = v8

Component: Comp3

\frac{d}{d time} (Comp3) = v9

Component: P1433

\frac{d}{d time} (P1433) = - (v8 + v9)

Component: MCIP_BMK1

\frac{d}{d time} (MCIP_BMK1) = v10a - v10b

Component: MCIPp_CaNc_star

\frac{d}{d time} (MCIPp_CaNc_star) = v11a - v11b

Component: MCIPp_GSK3betac

\frac{d}{d time} (MCIPp_GSK3betac) = v12a - v12b

Component: MCIPpp_CaNc_star

\frac{d}{d time} (MCIPpp_CaNc_star) = v13a - v13b

Component: NFATpc_CaNc_star

\frac{d}{d time} (NFATpc_CaNc_star) = v14a - v14b

Component: NFATc_GSK3betac

\frac{d}{d time} (NFATc_GSK3betac) = v15a - v15b

Component: NFATpn_CaNn_star

\frac{d}{d time} (NFATpn_CaNn_star) = v16a - v16b

Component: NFATn_GSK3betan

\frac{d}{d time} (NFATn_GSK3betan) = v17a - v17b

Component: v1

v1 = k29 NFATc

Component: v2

v2 = k30 NFATpn

Component: v3

v3 = k31 GSK3betac - (k32 GSK3betan)

Component: v4

v4 = k33 CaNc_star - (k34 CaNn_star)

Component: v5

v5 = k1 CaM {Ca}^{4} - (k2 CaMCa)

Component: v6

v6 = k3 CaMCa CaNc - (k4 CaNc_star)

Component: v7

v7 = k5 CaNc_star MCIP - (k6 Comp1)

Component: v8

v8 = k19 P1433 MCIPpp - (k20 Comp2)

Component: v9

v9 = k27 NFATpc P1433 - (k28 Comp3)

Component: v10

v10a = k7 MCIP BMK1 - (k8 MCIP_BMK1) v10b = k9 MCIP_BMK1 v10 = v10a + v10b

Component: v11

v11a = k10 MCIPp CaNc_star - (k11 MCIPp_CaNc_star) v11b = k12 MCIPp_CaNc_star v11 = v11a + v11b

Component: v12

v12a = k13 MCIPp GSK3betac - (k14 MCIPp_GSK3betac) v12b = k15 MCIPp_GSK3betac v12 = v12a + v12b

Component: v13

v13a = k16 MCIPpp CaNc_star - (k17 MCIPpp_CaNc_star) v13b = k18 MCIPpp_CaNc_star v13 = v13a + v13b

Component: v14

v14a = k21 NFATpc CaNc_star - (k22 NFATpc_CaNc_star) v14b = k23 NFATpc_CaNc_star v14 = v14a + v14b

Component: v15

v15a = k24 NFATc GSK3betac - (k25 NFATc_GSK3betac) v15b = k26 NFATc_GSK3betac v15 = v15a + v15b

Component: v16

v16a = k35 NFATpn CaNn_star - (k36 NFATpn_CaNn_star) v16b = k37 NFATpn_CaNn_star v16 = v16a + v16b

Component: v17

v17a = k38 NFATn GSK3betan - (k39 NFATn_GSK3betan) v17b = k40 NFATn_GSK3betan v17 = v17a + v17b

Component: v18

v18 = k41 NFATn - (k42 MRNA)

Component: v19

v19 = k43 MRNA - (\frac{\ln 2.0}{t_half} MCIP)

Model Mathematics

Component: environment

Component: BMK1

Component: MRNA

Component: NFATc

Component: NFATn

Component: NFATpc

Component: NFATpn

Component: GSK3betac

Component: GSK3betan

Component: CaNc

Component: CaNc_star

Component: CaNn_star

Component: CaNn

Component: CaM

Component: CaMCa

Component: MCIP

Component: MCIPp

Component: MCIPpp

Component: Comp1

Component: Comp2

Component: Comp3

Component: P1433

Component: MCIP_BMK1

Component: MCIPp_CaNc_star

Component: MCIPp_GSK3betac

Component: MCIPpp_CaNc_star

Component: NFATpc_CaNc_star

Component: NFATc_GSK3betac

Component: NFATpn_CaNn_star

Component: NFATn_GSK3betan

Component: v1

Component: v2

Component: v3

Component: v4

Component: v5

Component: v6

Component: v7

Component: v8

Component: v9

Component: v10

Component: v11

Component: v12

Component: v13

Component: v14

Component: v15

Component: v16

Component: v17

Component: v18

Component: v19

Component: model_parameters