Generated Code
The following is c_ida code generated by the CellML API from this CellML file. (Back to language selection)
The raw code is available.
/*
There are a total of 56 entries in the algebraic variable array.
There are a total of 22 entries in each of the rate and state variable arrays.
There are a total of 70 entries in the constant variable array.
*/
/*
* VOI is time in component environment (second).
* STATES[0] is V in component membrane (millivolt).
* CONSTANTS[0] is R in component membrane (joule_per_kilomole_kelvin).
* CONSTANTS[1] is T in component membrane (kelvin).
* CONSTANTS[2] is F in component membrane (coulomb_per_mole).
* CONSTANTS[3] is Cm in component membrane (microF).
* ALGEBRAIC[6] is i_K1 in component time_independent_potassium_current (nanoA).
* ALGEBRAIC[37] is i_to in component transient_outward_current (nanoA).
* ALGEBRAIC[7] is i_Kr in component rapid_delayed_rectifier_potassium_current (nanoA).
* ALGEBRAIC[12] is i_Ks in component slow_delayed_rectifier_potassium_current (nanoA).
* ALGEBRAIC[24] is i_Ca_L_K_cyt in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[27] is i_Ca_L_K_ds in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[40] is i_NaK in component sodium_potassium_pump (nanoA).
* ALGEBRAIC[15] is i_Na in component fast_sodium_current (nanoA).
* ALGEBRAIC[22] is i_b_Na in component sodium_background_current (nanoA).
* ALGEBRAIC[21] is i_p_Na in component persistent_sodium_current (nanoA).
* ALGEBRAIC[25] is i_Ca_L_Na_cyt in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[28] is i_Ca_L_Na_ds in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[41] is i_NaCa_cyt in component sodium_calcium_exchanger (nanoA).
* ALGEBRAIC[42] is i_NaCa_ds in component sodium_calcium_exchanger (nanoA).
* ALGEBRAIC[23] is i_Ca_L_Ca_cyt in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[26] is i_Ca_L_Ca_ds in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[36] is i_b_Ca in component calcium_background_current (nanoA).
* ALGEBRAIC[0] is i_Stim in component membrane (nanoA).
* CONSTANTS[4] is stim_start in component membrane (second).
* CONSTANTS[5] is stim_end in component membrane (second).
* CONSTANTS[6] is stim_period in component membrane (second).
* CONSTANTS[7] is stim_duration in component membrane (second).
* CONSTANTS[8] is stim_amplitude in component membrane (nanoA).
* ALGEBRAIC[1] is E_Na in component reversal_potentials (millivolt).
* ALGEBRAIC[2] is E_K in component reversal_potentials (millivolt).
* ALGEBRAIC[3] is E_Ks in component reversal_potentials (millivolt).
* ALGEBRAIC[4] is E_Ca in component reversal_potentials (millivolt).
* ALGEBRAIC[5] is E_mh in component reversal_potentials (millivolt).
* CONSTANTS[9] is P_kna in component reversal_potentials (dimensionless).
* CONSTANTS[10] is K_o in component extracellular_potassium_concentration (millimolar).
* CONSTANTS[11] is Na_o in component extracellular_sodium_concentration (millimolar).
* STATES[1] is K_i in component intracellular_potassium_concentration (millimolar).
* STATES[2] is Na_i in component intracellular_sodium_concentration (millimolar).
* CONSTANTS[12] is Ca_o in component extracellular_calcium_concentration (millimolar).
* STATES[3] is Ca_i in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[13] is K_mk1 in component time_independent_potassium_current (millimolar).
* CONSTANTS[14] is g_K1 in component time_independent_potassium_current (microS).
* CONSTANTS[15] is g_Kr1 in component rapid_delayed_rectifier_potassium_current (microS).
* CONSTANTS[16] is g_Kr2 in component rapid_delayed_rectifier_potassium_current (microS).
* STATES[4] is xr1 in component rapid_delayed_rectifier_potassium_current_xr1_gate (dimensionless).
* STATES[5] is xr2 in component rapid_delayed_rectifier_potassium_current_xr2_gate (dimensionless).
* ALGEBRAIC[8] is alpha_xr1 in component rapid_delayed_rectifier_potassium_current_xr1_gate (per_second).
* ALGEBRAIC[9] is beta_xr1 in component rapid_delayed_rectifier_potassium_current_xr1_gate (per_second).
* ALGEBRAIC[10] is alpha_xr2 in component rapid_delayed_rectifier_potassium_current_xr2_gate (per_second).
* ALGEBRAIC[11] is beta_xr2 in component rapid_delayed_rectifier_potassium_current_xr2_gate (per_second).
* CONSTANTS[17] is g_Ks in component slow_delayed_rectifier_potassium_current (microS).
* STATES[6] is xs in component slow_delayed_rectifier_potassium_current_xs_gate (dimensionless).
* ALGEBRAIC[13] is alpha_xs in component slow_delayed_rectifier_potassium_current_xs_gate (per_second).
* ALGEBRAIC[14] is beta_xs in component slow_delayed_rectifier_potassium_current_xs_gate (per_second).
* CONSTANTS[18] is g_Na in component fast_sodium_current (microS).
* STATES[7] is m in component fast_sodium_current_m_gate (dimensionless).
* STATES[8] is h in component fast_sodium_current_h_gate (dimensionless).
* ALGEBRAIC[17] is alpha_m in component fast_sodium_current_m_gate (per_second).
* ALGEBRAIC[18] is beta_m in component fast_sodium_current_m_gate (per_second).
* CONSTANTS[19] is delta_m in component fast_sodium_current_m_gate (millivolt).
* ALGEBRAIC[16] is E0_m in component fast_sodium_current_m_gate (millivolt).
* ALGEBRAIC[19] is alpha_h in component fast_sodium_current_h_gate (per_second).
* ALGEBRAIC[20] is beta_h in component fast_sodium_current_h_gate (per_second).
* CONSTANTS[20] is shift_h in component fast_sodium_current_h_gate (millivolt).
* CONSTANTS[21] is g_pna in component persistent_sodium_current (microS).
* CONSTANTS[22] is g_bna in component sodium_background_current (microS).
* ALGEBRAIC[29] is i_Ca_L in component L_type_Ca_channel (nanoA).
* CONSTANTS[23] is P_Ca_L in component L_type_Ca_channel (nanoA_per_millimolar).
* CONSTANTS[24] is P_CaK in component L_type_Ca_channel (dimensionless).
* CONSTANTS[25] is P_CaNa in component L_type_Ca_channel (dimensionless).
* STATES[9] is Ca_ds in component intracellular_calcium_concentration (millimolar).
* STATES[10] is d in component L_type_Ca_channel_d_gate (dimensionless).
* STATES[11] is f in component L_type_Ca_channel_f_gate (dimensionless).
* STATES[12] is f2 in component L_type_Ca_channel_f2_gate (dimensionless).
* STATES[13] is f2ds in component L_type_Ca_channel_f2ds_gate (dimensionless).
* CONSTANTS[26] is Km_f2 in component L_type_Ca_channel (millimolar).
* CONSTANTS[27] is Km_f2ds in component L_type_Ca_channel (millimolar).
* CONSTANTS[28] is R_decay in component L_type_Ca_channel (per_second).
* CONSTANTS[29] is FrICa in component L_type_Ca_channel (dimensionless).
* ALGEBRAIC[31] is alpha_d in component L_type_Ca_channel_d_gate (per_second).
* ALGEBRAIC[32] is beta_d in component L_type_Ca_channel_d_gate (per_second).
* ALGEBRAIC[30] is E0_d in component L_type_Ca_channel_d_gate (millivolt).
* CONSTANTS[30] is speed_d in component L_type_Ca_channel_d_gate (dimensionless).
* ALGEBRAIC[34] is alpha_f in component L_type_Ca_channel_f_gate (per_second).
* ALGEBRAIC[35] is beta_f in component L_type_Ca_channel_f_gate (per_second).
* CONSTANTS[31] is speed_f in component L_type_Ca_channel_f_gate (dimensionless).
* CONSTANTS[32] is delta_f in component L_type_Ca_channel_f_gate (millivolt).
* ALGEBRAIC[33] is E0_f in component L_type_Ca_channel_f_gate (millivolt).
* CONSTANTS[33] is g_bca in component calcium_background_current (microS).
* CONSTANTS[34] is g_to in component transient_outward_current (microS).
* CONSTANTS[35] is g_tos in component transient_outward_current (dimensionless).
* STATES[14] is s in component transient_outward_current_s_gate (dimensionless).
* STATES[15] is r in component transient_outward_current_r_gate (dimensionless).
* ALGEBRAIC[38] is alpha_s in component transient_outward_current_s_gate (per_second).
* ALGEBRAIC[39] is beta_s in component transient_outward_current_s_gate (per_second).
* CONSTANTS[36] is i_NaK_max in component sodium_potassium_pump (nanoA).
* CONSTANTS[37] is K_mK in component sodium_potassium_pump (millimolar).
* CONSTANTS[38] is K_mNa in component sodium_potassium_pump (millimolar).
* ALGEBRAIC[43] is i_NaCa in component sodium_calcium_exchanger (nanoA).
* CONSTANTS[39] is k_NaCa in component sodium_calcium_exchanger (nanoA).
* CONSTANTS[40] is n_NaCa in component sodium_calcium_exchanger (dimensionless).
* CONSTANTS[41] is d_NaCa in component sodium_calcium_exchanger (dimensionless).
* CONSTANTS[42] is gamma in component sodium_calcium_exchanger (dimensionless).
* CONSTANTS[43] is FRiNaCa in component sodium_calcium_exchanger (dimensionless).
* ALGEBRAIC[45] is i_up in component sarcoplasmic_reticulum_calcium_pump (millimolar_per_second).
* CONSTANTS[67] is K_1 in component sarcoplasmic_reticulum_calcium_pump (dimensionless).
* ALGEBRAIC[44] is K_2 in component sarcoplasmic_reticulum_calcium_pump (millimolar).
* CONSTANTS[44] is K_cyca in component sarcoplasmic_reticulum_calcium_pump (millimolar).
* CONSTANTS[45] is K_xcs in component sarcoplasmic_reticulum_calcium_pump (dimensionless).
* CONSTANTS[46] is K_srca in component sarcoplasmic_reticulum_calcium_pump (millimolar).
* CONSTANTS[47] is alpha_up in component sarcoplasmic_reticulum_calcium_pump (millimolar_per_second).
* CONSTANTS[48] is beta_up in component sarcoplasmic_reticulum_calcium_pump (millimolar_per_second).
* STATES[16] is Ca_up in component intracellular_calcium_concentration (millimolar).
* ALGEBRAIC[46] is i_trans in component calcium_translocation (millimolar_per_second).
* STATES[17] is Ca_rel in component intracellular_calcium_concentration (millimolar).
* ALGEBRAIC[55] is i_rel in component calcium_release (millimolar_per_second).
* ALGEBRAIC[47] is VoltDep in component calcium_release (dimensionless).
* ALGEBRAIC[50] is RegBindSite in component calcium_release (dimensionless).
* ALGEBRAIC[48] is CaiReg in component calcium_release (dimensionless).
* ALGEBRAIC[49] is CadsReg in component calcium_release (dimensionless).
* ALGEBRAIC[51] is ActRate in component calcium_release (per_second).
* ALGEBRAIC[52] is InactRate in component calcium_release (per_second).
* CONSTANTS[49] is K_leak_rate in component calcium_release (per_second).
* CONSTANTS[50] is K_m_rel in component calcium_release (per_second).
* CONSTANTS[51] is K_m_Ca_cyt in component calcium_release (millimolar).
* CONSTANTS[52] is K_m_Ca_ds in component calcium_release (millimolar).
* ALGEBRAIC[54] is PrecFrac in component calcium_release (dimensionless).
* STATES[18] is ActFrac in component calcium_release (dimensionless).
* STATES[19] is ProdFrac in component calcium_release (dimensionless).
* ALGEBRAIC[53] is SpeedRel in component calcium_release (dimensionless).
* CONSTANTS[69] is V_i in component intracellular_calcium_concentration (micrometre3).
* STATES[20] is Ca_Calmod in component intracellular_calcium_concentration (millimolar).
* STATES[21] is Ca_Trop in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[53] is Calmod in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[54] is Trop in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[55] is alpha_Calmod in component intracellular_calcium_concentration (per_millimolar_second).
* CONSTANTS[56] is beta_Calmod in component intracellular_calcium_concentration (per_second).
* CONSTANTS[57] is alpha_Trop in component intracellular_calcium_concentration (per_millimolar_second).
* CONSTANTS[58] is beta_Trop in component intracellular_calcium_concentration (per_second).
* CONSTANTS[59] is radius in component intracellular_calcium_concentration (micrometre).
* CONSTANTS[60] is length in component intracellular_calcium_concentration (micrometre).
* CONSTANTS[66] is V_Cell in component intracellular_calcium_concentration (micrometre3).
* CONSTANTS[68] is V_i_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[61] is V_ds_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[62] is V_rel_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[63] is V_e_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[64] is V_up_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[65] is Kdecay in component intracellular_calcium_concentration (per_second).
* RATES[0] is d/dt V in component membrane (millivolt).
* RATES[4] is d/dt xr1 in component rapid_delayed_rectifier_potassium_current_xr1_gate (dimensionless).
* RATES[5] is d/dt xr2 in component rapid_delayed_rectifier_potassium_current_xr2_gate (dimensionless).
* RATES[6] is d/dt xs in component slow_delayed_rectifier_potassium_current_xs_gate (dimensionless).
* RATES[7] is d/dt m in component fast_sodium_current_m_gate (dimensionless).
* RATES[8] is d/dt h in component fast_sodium_current_h_gate (dimensionless).
* RATES[10] is d/dt d in component L_type_Ca_channel_d_gate (dimensionless).
* RATES[11] is d/dt f in component L_type_Ca_channel_f_gate (dimensionless).
* RATES[12] is d/dt f2 in component L_type_Ca_channel_f2_gate (dimensionless).
* RATES[13] is d/dt f2ds in component L_type_Ca_channel_f2ds_gate (dimensionless).
* RATES[14] is d/dt s in component transient_outward_current_s_gate (dimensionless).
* RATES[15] is d/dt r in component transient_outward_current_r_gate (dimensionless).
* RATES[18] is d/dt ActFrac in component calcium_release (dimensionless).
* RATES[19] is d/dt ProdFrac in component calcium_release (dimensionless).
* RATES[2] is d/dt Na_i in component intracellular_sodium_concentration (millimolar).
* RATES[1] is d/dt K_i in component intracellular_potassium_concentration (millimolar).
* RATES[3] is d/dt Ca_i in component intracellular_calcium_concentration (millimolar).
* RATES[20] is d/dt Ca_Calmod in component intracellular_calcium_concentration (millimolar).
* RATES[21] is d/dt Ca_Trop in component intracellular_calcium_concentration (millimolar).
* RATES[9] is d/dt Ca_ds in component intracellular_calcium_concentration (millimolar).
* RATES[16] is d/dt Ca_up in component intracellular_calcium_concentration (millimolar).
* RATES[17] is d/dt Ca_rel in component intracellular_calcium_concentration (millimolar).
* There are a total of 8 condition variables.
*/
void
initConsts(double* CONSTANTS, double* RATES, double *STATES)
{
STATES[0] = -92.849333;
CONSTANTS[0] = 8314.472;
CONSTANTS[1] = 310;
CONSTANTS[2] = 96485.3415;
CONSTANTS[3] = 9.5e-5;
CONSTANTS[4] = 0.1;
CONSTANTS[5] = 100000;
CONSTANTS[6] = 1;
CONSTANTS[7] = 0.003;
CONSTANTS[8] = -3;
CONSTANTS[9] = 0.03;
CONSTANTS[10] = 4;
CONSTANTS[11] = 140;
STATES[1] = 136.5644281;
STATES[2] = 7.3321223;
CONSTANTS[12] = 2;
STATES[3] = 1.4e-5;
CONSTANTS[13] = 10;
CONSTANTS[14] = 0.5;
CONSTANTS[15] = 0.0021;
CONSTANTS[16] = 0.0013;
STATES[4] = 1.03e-5;
STATES[5] = 2e-7;
CONSTANTS[17] = 0.0026;
STATES[6] = 0.001302;
CONSTANTS[18] = 2.5;
STATES[7] = 0.0016203;
STATES[8] = 0.9944036;
CONSTANTS[19] = 1e-5;
CONSTANTS[20] = 0;
CONSTANTS[21] = 0.004;
CONSTANTS[22] = 0.0006;
CONSTANTS[23] = 0.1;
CONSTANTS[24] = 0.002;
CONSTANTS[25] = 0.01;
STATES[9] = 1.88e-5;
STATES[10] = 0;
STATES[11] = 1;
STATES[12] = 0.9349197;
STATES[13] = 0.9651958;
CONSTANTS[26] = 100000;
CONSTANTS[27] = 0.001;
CONSTANTS[28] = 20;
CONSTANTS[29] = 1;
CONSTANTS[30] = 3;
CONSTANTS[31] = 0.3;
CONSTANTS[32] = 0.0001;
CONSTANTS[33] = 0.00025;
CONSTANTS[34] = 0.005;
CONSTANTS[35] = 0;
STATES[14] = 0.9948645;
STATES[15] = 0;
CONSTANTS[36] = 0.7;
CONSTANTS[37] = 1;
CONSTANTS[38] = 40;
CONSTANTS[39] = 0.0005;
CONSTANTS[40] = 3;
CONSTANTS[41] = 0;
CONSTANTS[42] = 0.5;
CONSTANTS[43] = 0.001;
CONSTANTS[44] = 0.0003;
CONSTANTS[45] = 0.4;
CONSTANTS[46] = 0.5;
CONSTANTS[47] = 0.4;
CONSTANTS[48] = 0.03;
STATES[16] = 0.4531889;
STATES[17] = 0.4481927;
CONSTANTS[49] = 0.05;
CONSTANTS[50] = 250;
CONSTANTS[51] = 0.0005;
CONSTANTS[52] = 0.01;
STATES[18] = 0.0042614;
STATES[19] = 0.4068154;
STATES[20] = 0.0005555;
STATES[21] = 0.0003542;
CONSTANTS[53] = 0.02;
CONSTANTS[54] = 0.05;
CONSTANTS[55] = 100000;
CONSTANTS[56] = 50;
CONSTANTS[57] = 100000;
CONSTANTS[58] = 200;
CONSTANTS[59] = 0.012;
CONSTANTS[60] = 0.074;
CONSTANTS[61] = 0.1;
CONSTANTS[62] = 0.1;
CONSTANTS[63] = 0.4;
CONSTANTS[64] = 0.01;
CONSTANTS[65] = 10;
CONSTANTS[66] = 3.14159*pow(CONSTANTS[59], 2.00000)*CONSTANTS[60];
CONSTANTS[67] = ( CONSTANTS[44]*CONSTANTS[45])/CONSTANTS[46];
CONSTANTS[68] = ((1.00000 - CONSTANTS[63]) - CONSTANTS[64]) - CONSTANTS[62];
CONSTANTS[69] = CONSTANTS[66]*CONSTANTS[68];
RATES[0] = 0.1001;
RATES[4] = 0.1001;
RATES[5] = 0.1001;
RATES[6] = 0.1001;
RATES[7] = 0.1001;
RATES[8] = 0.1001;
RATES[10] = 0.1001;
RATES[11] = 0.1001;
RATES[12] = 0.1001;
RATES[13] = 0.1001;
RATES[14] = 0.1001;
RATES[15] = 0.1001;
RATES[18] = 0.1001;
RATES[19] = 0.1001;
RATES[2] = 0.1001;
RATES[1] = 0.1001;
RATES[3] = 0.1001;
RATES[20] = 0.1001;
RATES[21] = 0.1001;
RATES[9] = 0.1001;
RATES[16] = 0.1001;
RATES[17] = 0.1001;
}
void
computeResiduals(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
resid[0] = RATES[0] - (- 1.00000/CONSTANTS[3])*(ALGEBRAIC[0]+ALGEBRAIC[6]+ALGEBRAIC[37]+ALGEBRAIC[7]+ALGEBRAIC[12]+ALGEBRAIC[40]+ALGEBRAIC[15]+ALGEBRAIC[22]+ALGEBRAIC[21]+ALGEBRAIC[25]+ALGEBRAIC[28]+ALGEBRAIC[41]+ALGEBRAIC[42]+ALGEBRAIC[23]+ALGEBRAIC[26]+ALGEBRAIC[24]+ALGEBRAIC[27]+ALGEBRAIC[36]);
resid[1] = RATES[4] - ALGEBRAIC[8]*(1.00000 - STATES[4]) - ALGEBRAIC[9]*STATES[4];
resid[2] = RATES[5] - ALGEBRAIC[10]*(1.00000 - STATES[5]) - ALGEBRAIC[11]*STATES[5];
resid[3] = RATES[6] - ALGEBRAIC[13]*(1.00000 - STATES[6]) - ALGEBRAIC[14]*STATES[6];
resid[4] = RATES[7] - ALGEBRAIC[17]*(1.00000 - STATES[7]) - ALGEBRAIC[18]*STATES[7];
resid[5] = RATES[8] - ALGEBRAIC[19]*(1.00000 - STATES[8]) - ALGEBRAIC[20]*STATES[8];
resid[6] = RATES[10] - CONSTANTS[30]*( ALGEBRAIC[31]*(1.00000 - STATES[10]) - ALGEBRAIC[32]*STATES[10]);
resid[7] = RATES[11] - CONSTANTS[31]*( ALGEBRAIC[34]*(1.00000 - STATES[11]) - ALGEBRAIC[35]*STATES[11]);
resid[8] = RATES[12] - 1.00000 - 1.00000*(STATES[3]/(CONSTANTS[26]+STATES[3])+STATES[12]);
resid[9] = RATES[13] - CONSTANTS[28]*(1.00000 - (STATES[9]/(CONSTANTS[27]+STATES[9])+STATES[13]));
resid[10] = RATES[14] - ALGEBRAIC[38]*(1.00000 - STATES[14]) - ALGEBRAIC[39]*STATES[14];
resid[11] = RATES[15] - 333.000*(1.00000/(1.00000+exp(- (STATES[0]+4.00000)/5.00000)) - STATES[15]);
resid[12] = RATES[18] - ALGEBRAIC[54]*ALGEBRAIC[53]*ALGEBRAIC[51] - STATES[18]*ALGEBRAIC[53]*ALGEBRAIC[52];
resid[13] = RATES[19] - STATES[18]*ALGEBRAIC[53]*ALGEBRAIC[52] - ALGEBRAIC[53]*1.00000*STATES[19];
resid[14] = RATES[2] - (- 1.00000/( 1.00000*CONSTANTS[69]*CONSTANTS[2]))*(ALGEBRAIC[15]+ALGEBRAIC[21]+ALGEBRAIC[22]+ 3.00000*ALGEBRAIC[40]+ 3.00000*ALGEBRAIC[41]+ALGEBRAIC[25]+ALGEBRAIC[28]);
resid[15] = RATES[1] - (- 1.00000/( 1.00000*CONSTANTS[69]*CONSTANTS[2]))*((ALGEBRAIC[6]+ALGEBRAIC[7]+ALGEBRAIC[12]+ALGEBRAIC[24]+ALGEBRAIC[27]+ALGEBRAIC[37]) - 2.00000*ALGEBRAIC[40]);
resid[16] = RATES[3] - ((( (- 1.00000/( 2.00000*1.00000*CONSTANTS[69]*CONSTANTS[2]))*(((ALGEBRAIC[23]+ALGEBRAIC[36]) - 2.00000*ALGEBRAIC[41]) - 2.00000*ALGEBRAIC[42])+ STATES[9]*CONSTANTS[61]*CONSTANTS[65]+( ALGEBRAIC[55]*CONSTANTS[62])/CONSTANTS[68]) - RATES[20]) - RATES[21]) - ALGEBRAIC[45];
resid[17] = RATES[9] - ( - 1.00000*ALGEBRAIC[26])/( 2.00000*1.00000*CONSTANTS[61]*CONSTANTS[69]*CONSTANTS[2]) - STATES[9]*CONSTANTS[65];
resid[18] = RATES[16] - (CONSTANTS[68]/CONSTANTS[64])*ALGEBRAIC[45] - ALGEBRAIC[46];
resid[19] = RATES[17] - (CONSTANTS[64]/CONSTANTS[62])*ALGEBRAIC[46] - ALGEBRAIC[55];
resid[20] = RATES[20] - CONSTANTS[55]*STATES[3]*(CONSTANTS[53] - STATES[20]) - CONSTANTS[56]*STATES[20];
resid[21] = RATES[21] - CONSTANTS[57]*STATES[3]*(CONSTANTS[54] - STATES[21]) - CONSTANTS[58]*STATES[21];
}
void
computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[29] = ALGEBRAIC[23]+ALGEBRAIC[24]+ALGEBRAIC[25]+ALGEBRAIC[26]+ALGEBRAIC[27]+ALGEBRAIC[28];
ALGEBRAIC[43] = ALGEBRAIC[41]+ALGEBRAIC[42];
}
void
computeEssentialVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[0] = (CONDVAR[0]>=0.00000&&CONDVAR[1]<=0.00000&&CONDVAR[2]<=0.00000 ? CONSTANTS[8] : 0.00000);
ALGEBRAIC[2] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[10]/STATES[1]);
ALGEBRAIC[6] = ( (( CONSTANTS[14]*CONSTANTS[10])/(CONSTANTS[10]+CONSTANTS[13]))*(STATES[0] - ALGEBRAIC[2]))/(1.00000+exp(( ((STATES[0] - ALGEBRAIC[2]) - 10.0000)*CONSTANTS[2]*1.25000)/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[7] = (( ( CONSTANTS[15]*STATES[4]+ CONSTANTS[16]*STATES[5])*1.00000)/(1.00000+exp((STATES[0]+9.00000)/22.4000)))*(STATES[0] - ALGEBRAIC[2]);
ALGEBRAIC[8] = 50.0000/(1.00000+exp(- (STATES[0] - 5.00000)/9.00000));
ALGEBRAIC[9] = 0.0500000*exp(- (STATES[0] - 20.0000)/15.0000);
ALGEBRAIC[10] = 50.0000/(1.00000+exp(- (STATES[0] - 5.00000)/9.00000));
ALGEBRAIC[11] = 0.400000*exp(- pow((STATES[0]+30.0000)/30.0000, 3.00000));
ALGEBRAIC[3] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log((CONSTANTS[10]+ CONSTANTS[9]*CONSTANTS[11])/(STATES[1]+ CONSTANTS[9]*STATES[2]));
ALGEBRAIC[12] = CONSTANTS[17]*pow(STATES[6], 2.00000)*(STATES[0] - ALGEBRAIC[3]);
ALGEBRAIC[13] = 14.0000/(1.00000+exp(- (STATES[0] - 40.0000)/9.00000));
ALGEBRAIC[14] = 1.00000*exp(- STATES[0]/45.0000);
ALGEBRAIC[5] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log((CONSTANTS[11]+ 0.120000*CONSTANTS[10])/(STATES[2]+ 0.120000*STATES[1]));
ALGEBRAIC[15] = CONSTANTS[18]*pow(STATES[7], 3.00000)*STATES[8]*(STATES[0] - ALGEBRAIC[5]);
ALGEBRAIC[16] = STATES[0]+41.0000;
ALGEBRAIC[17] = (CONDVAR[3]<0.00000 ? 2000.00 : ( 200.000*ALGEBRAIC[16])/(1.00000 - exp( - 0.100000*ALGEBRAIC[16])));
ALGEBRAIC[18] = 8000.00*exp( - 0.0560000*(STATES[0]+66.0000));
ALGEBRAIC[19] = 20.0000*exp( - 0.125000*((STATES[0]+75.0000) - CONSTANTS[20]));
ALGEBRAIC[20] = 2000.00/(1.00000+ 320.000*exp( - 0.100000*((STATES[0]+75.0000) - CONSTANTS[20])));
ALGEBRAIC[1] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[11]/STATES[2]);
ALGEBRAIC[21] = (( CONSTANTS[21]*1.00000)/(1.00000+exp(- (STATES[0]+52.0000)/8.00000)))*(STATES[0] - ALGEBRAIC[1]);
ALGEBRAIC[22] = CONSTANTS[22]*(STATES[0] - ALGEBRAIC[1]);
ALGEBRAIC[23] = ((( (1.00000 - CONSTANTS[29])*4.00000*CONSTANTS[23]*STATES[10]*STATES[11]*STATES[12]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2]*2.00000)/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[3]*exp(( 100.000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[12]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2]*2.00000)/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[24] = ((( (1.00000 - CONSTANTS[29])*CONSTANTS[24]*CONSTANTS[23]*STATES[10]*STATES[11]*STATES[12]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[1]*exp(( 50.0000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[10]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[25] = ((( (1.00000 - CONSTANTS[29])*CONSTANTS[25]*CONSTANTS[23]*STATES[10]*STATES[11]*STATES[12]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[2]*exp(( 50.0000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[11]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[26] = ((( CONSTANTS[29]*4.00000*CONSTANTS[23]*STATES[10]*STATES[11]*STATES[13]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2]*2.00000)/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[3]*exp(( 100.000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[12]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2]*2.00000)/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[27] = ((( CONSTANTS[29]*CONSTANTS[24]*CONSTANTS[23]*STATES[10]*STATES[11]*STATES[13]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[1]*exp(( 50.0000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[10]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[28] = ((( CONSTANTS[29]*CONSTANTS[25]*CONSTANTS[23]*STATES[10]*STATES[11]*STATES[13]*(STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))/(1.00000 - exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))*( STATES[2]*exp(( 50.0000*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])) - CONSTANTS[11]*exp(( - (STATES[0] - 50.0000)*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[30] = (STATES[0]+24.0000) - 5.00000;
ALGEBRAIC[31] = (CONDVAR[4]<0.00000 ? 120.000 : ( 30.0000*ALGEBRAIC[30])/(1.00000 - exp(- ALGEBRAIC[30]/4.00000)));
ALGEBRAIC[32] = (CONDVAR[5]<0.00000 ? 120.000 : ( 12.0000*ALGEBRAIC[30])/(exp(ALGEBRAIC[30]/10.0000) - 1.00000));
ALGEBRAIC[33] = STATES[0]+34.0000;
ALGEBRAIC[34] = (CONDVAR[6]<0.00000 ? 25.0000 : ( 6.25000*ALGEBRAIC[33])/(exp(ALGEBRAIC[33]/4.00000) - 1.00000));
ALGEBRAIC[35] = 12.0000/(1.00000+exp(( - 1.00000*(STATES[0]+34.0000))/4.00000));
ALGEBRAIC[4] = (( 0.500000*CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[12]/STATES[3]);
ALGEBRAIC[36] = CONSTANTS[33]*(STATES[0] - ALGEBRAIC[4]);
ALGEBRAIC[37] = CONSTANTS[34]*(CONSTANTS[35]+ STATES[14]*(1.00000 - CONSTANTS[35]))*STATES[15]*(STATES[0] - ALGEBRAIC[2]);
ALGEBRAIC[38] = 0.0330000*exp(- STATES[0]/17.0000);
ALGEBRAIC[39] = 33.0000/(1.00000+exp( - 0.125000*(STATES[0]+10.0000)));
ALGEBRAIC[40] = ( (( CONSTANTS[36]*CONSTANTS[10])/(CONSTANTS[37]+CONSTANTS[10]))*STATES[2])/(CONSTANTS[38]+STATES[2]);
ALGEBRAIC[41] = ( (1.00000 - CONSTANTS[43])*CONSTANTS[39]*( exp(( CONSTANTS[42]*(CONSTANTS[40] - 2.00000)*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))*pow(STATES[2], CONSTANTS[40])*CONSTANTS[12] - exp(( (CONSTANTS[42] - 1.00000)*(CONSTANTS[40] - 2.00000)*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))*pow(CONSTANTS[11], CONSTANTS[40])*STATES[3]))/( (1.00000+ CONSTANTS[41]*( STATES[3]*pow(CONSTANTS[11], CONSTANTS[40])+ CONSTANTS[12]*pow(STATES[2], CONSTANTS[40])))*(1.00000+STATES[3]/0.00690000));
ALGEBRAIC[42] = ( CONSTANTS[43]*CONSTANTS[39]*( exp(( CONSTANTS[42]*(CONSTANTS[40] - 2.00000)*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))*pow(STATES[2], CONSTANTS[40])*CONSTANTS[12] - exp(( (CONSTANTS[42] - 1.00000)*(CONSTANTS[40] - 2.00000)*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))*pow(CONSTANTS[11], CONSTANTS[40])*STATES[9]))/( (1.00000+ CONSTANTS[41]*( STATES[9]*pow(CONSTANTS[11], CONSTANTS[40])+ CONSTANTS[12]*pow(STATES[2], CONSTANTS[40])))*(1.00000+STATES[9]/0.00690000));
ALGEBRAIC[44] = STATES[3]+ STATES[16]*CONSTANTS[67]+ CONSTANTS[44]*CONSTANTS[45]+CONSTANTS[44];
ALGEBRAIC[45] = (STATES[3]/ALGEBRAIC[44])*CONSTANTS[47] - (( STATES[16]*CONSTANTS[67])/ALGEBRAIC[44])*CONSTANTS[48];
ALGEBRAIC[46] = 50.0000*(STATES[16] - STATES[17]);
ALGEBRAIC[47] = exp( 0.0800000*(STATES[0] - 40.0000));
ALGEBRAIC[48] = STATES[3]/(STATES[3]+CONSTANTS[51]);
ALGEBRAIC[49] = STATES[9]/(STATES[9]+CONSTANTS[52]);
ALGEBRAIC[50] = ALGEBRAIC[48]+ (1.00000 - ALGEBRAIC[48])*ALGEBRAIC[49];
ALGEBRAIC[51] = 0.00000*ALGEBRAIC[47]+ 500.000*pow(ALGEBRAIC[50], 2.00000);
ALGEBRAIC[52] = 60.0000+ 500.000*pow(ALGEBRAIC[50], 2.00000);
ALGEBRAIC[53] = (CONDVAR[7]<0.00000 ? 5.00000 : 1.00000);
ALGEBRAIC[54] = (1.00000 - STATES[18]) - STATES[19];
ALGEBRAIC[55] = ( pow(STATES[18]/(STATES[18]+0.250000), 2.00000)*CONSTANTS[50]+CONSTANTS[49])*STATES[17];
}
void
getStateInformation(double* SI)
{
SI[0] = 1.0;
SI[1] = 1.0;
SI[2] = 1.0;
SI[3] = 1.0;
SI[4] = 1.0;
SI[5] = 1.0;
SI[6] = 1.0;
SI[7] = 1.0;
SI[8] = 1.0;
SI[9] = 1.0;
SI[10] = 1.0;
SI[11] = 1.0;
SI[12] = 1.0;
SI[13] = 1.0;
SI[14] = 1.0;
SI[15] = 1.0;
SI[16] = 1.0;
SI[17] = 1.0;
SI[18] = 1.0;
SI[19] = 1.0;
SI[20] = 1.0;
SI[21] = 1.0;
}
void
computeRoots(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
CONDVAR[0] = VOI - CONSTANTS[4];
CONDVAR[1] = VOI - CONSTANTS[5];
CONDVAR[2] = ((VOI - CONSTANTS[4]) - floor((VOI - CONSTANTS[4])/CONSTANTS[6])*CONSTANTS[6]) - CONSTANTS[7];
CONDVAR[3] = fabs(ALGEBRAIC[16]) - CONSTANTS[19];
CONDVAR[4] = fabs(ALGEBRAIC[30]) - 0.000100000;
CONDVAR[5] = fabs(ALGEBRAIC[30]) - 0.000100000;
CONDVAR[6] = fabs(ALGEBRAIC[33]) - CONSTANTS[32];
CONDVAR[7] = STATES[0] - - 50.0000;
}