You are here: Home / Exposures / Potter, Greller, Cho, Nuttall, Stroup, Suva, Tobin, 2005 / Response to continuous and pulsatile PTH dosing: a mathematical model for parathyroid hormone receptor kinetics

Model Mathematics

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Component: environment

Component: P

\frac{d}{d time} (P) = k1_Ca + k2_Ci + D - (k1 Ra P + k2 Ri P + kcl P)

Component: Ra

\frac{d}{d time} (Ra) = k1_Ca + k3 Ri - (k1 Ra P + k3_Ra)

Component: Ri

\frac{d}{d time} (Ri) = k2_Ci + k3_Ra - (k2 Ri P + k3 Ri)

Component: Ca

\frac{d}{d time} (Ca) = k1 Ra P + k4 Ci - (k1_Ca + k4_Ca)

Component: Ci

\frac{d}{d time} (Ci) = k2 Ri P + k4_Ca - (k2_Ci + k4 Ci)

Component: rho

rho = \frac{Ra + Ca}{Ra + Ca + Ri + Ci}

Component: model_parameters

D = De + Dd

Source: Derived from workspace Potter, Greller, Cho, Nuttall, Stroup, Suva, Tobin, 2005 at changeset 5a3fc2158228.; This exposure was expired. A more up-to-date exposure is available, or view related resources.

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License: This work is licensed under a Creative Commons Attribution 3.0 Unported License.

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