Model Mathematics

Component: environment

Component: membrane

dd time V =- i_CaL + i_CaT + i_K_DR + i_K_Ca + i_Leak Cm

Component: reversal_potentials

E_Ca = V ⁢ Cai - Cae ⁢ⅇ- 2.0 ⁢ F ⁢ V R ⁢ T 1.0 -ⅇ- 2.0 ⁢ F ⁢ V R ⁢ T E_K = V ⁢ Ki - Ke ⁢ⅇ- F ⁢ V R ⁢ T 1.0 -ⅇ- F ⁢ V R ⁢ T

Component: L_type_calcium_channel_current

i_CaL = g_CaL ⁢ m 2.0 ⁢ E_Ca

Component: L_type_calcium_channel_current_m_gate

m_infinity = 1.0 1.0 +ⅇ- V - -12.0 12.0 tau_m = tau_m_ ⅇ V - -60.0 22.0 + 2.0 ⁢ⅇ- 2.0 ⁢ V - -60.0 22.0 dd time m = m_infinity - m tau_m

Component: T_type_calcium_channel_current

Component: T_type_calcium_channel_current_m_gate

m_infinity = 1.0 1.0 +ⅇ- V - -30.0 10.5 tau_m = tau_m_ ⅇ V - -60.0 22.0 + 2.0 ⁢ⅇ- 2.0 ⁢ V - -60.0 22.0 dd time m = m_infinity - m tau_m

Component: T_type_calcium_channel_current_h_gate

h_infinity = 1.0 1.0 +ⅇ V - -57.0 5.0 dd time h = h_infinity - h tau_h

Component: voltage_sensitive_potassium_current

Component: voltage_sensitive_potassium_current_n_gate

n_infinity = 1.0 1.0 +ⅇ- V - -20.0 4.5 dd time n = n_infinity - n tau_n

Component: calcium_activated_potassium_current

Component: leak_current

Component: intracellular_calcium_concentration

Component: intracellular_calcium_dynamics

j_exch = Ca_eq - Cai tau j_in =- alpha ⁢ i_CaL + i_CaT j_eff = vp ⁢ Cai 2.0 Cai 2.0 + Kp 2.0