Model Mathematics

Component: synaptic_coupling

sum_g_syn_e_s = g_syn_e_1_2 ⁢ s1 + g_syn_e_1_3 ⁢ s1 + g_syn_e_1_4 ⁢ s1 + g_syn_e_1_5 ⁢ s1 + g_syn_e_1_6 ⁢ s1 + g_syn_e_1_7 ⁢ s1 + g_syn_e_1_8 ⁢ s1 + g_syn_e_1_9 ⁢ s1 + g_syn_e_1_10 ⁢ s1 + g_syn_e_2_1 ⁢ s2 + g_syn_e_2_3 ⁢ s2 + g_syn_e_2_4 ⁢ s2 + g_syn_e_2_5 ⁢ s2 + g_syn_e_2_6 ⁢ s2 + g_syn_e_2_7 ⁢ s2 + g_syn_e_2_8 ⁢ s2 + g_syn_e_2_9 ⁢ s2 + g_syn_e_2_10 ⁢ s2 + g_syn_e_3_1 ⁢ s3 + g_syn_e_3_2 ⁢ s3 + g_syn_e_3_4 ⁢ s3 + g_syn_e_3_5 ⁢ s3 + g_syn_e_3_6 ⁢ s3 + g_syn_e_3_7 ⁢ s3 + g_syn_e_3_8 ⁢ s3 + g_syn_e_3_9 ⁢ s3 + g_syn_e_3_10 ⁢ s3 + g_syn_e_4_1 ⁢ s4 + g_syn_e_4_2 ⁢ s4 + g_syn_e_4_3 ⁢ s4 + g_syn_e_4_5 ⁢ s4 + g_syn_e_4_6 ⁢ s4 + g_syn_e_4_7 ⁢ s4 + g_syn_e_4_8 ⁢ s4 + g_syn_e_4_9 ⁢ s4 + g_syn_e_4_10 ⁢ s4 + g_syn_e_5_1 ⁢ s5 + g_syn_e_5_2 ⁢ s5 + g_syn_e_5_3 ⁢ s5 + g_syn_e_5_4 ⁢ s5 + g_syn_e_5_6 ⁢ s5 + g_syn_e_5_7 ⁢ s5 + g_syn_e_5_8 ⁢ s5 + g_syn_e_5_9 ⁢ s5 + g_syn_e_5_10 ⁢ s5 + g_syn_e_6_1 ⁢ s6 + g_syn_e_6_2 ⁢ s6 + g_syn_e_6_3 ⁢ s6 + g_syn_e_6_4 ⁢ s6 + g_syn_e_6_5 ⁢ s6 + g_syn_e_6_7 ⁢ s6 + g_syn_e_6_8 ⁢ s6 + g_syn_e_6_9 ⁢ s6 + g_syn_e_6_10 ⁢ s6 + g_syn_e_7_1 ⁢ s7 + g_syn_e_7_2 ⁢ s7 + g_syn_e_7_3 ⁢ s7 + g_syn_e_7_4 ⁢ s7 + g_syn_e_7_5 ⁢ s7 + g_syn_e_7_6 ⁢ s7 + g_syn_e_7_8 ⁢ s7 + g_syn_e_7_9 ⁢ s7 + g_syn_e_7_10 ⁢ s7 + g_syn_e_8_1 ⁢ s8 + g_syn_e_8_2 ⁢ s8 + g_syn_e_8_3 ⁢ s8 + g_syn_e_8_4 ⁢ s8 + g_syn_e_8_5 ⁢ s8 + g_syn_e_8_6 ⁢ s8 + g_syn_e_8_7 ⁢ s8 + g_syn_e_8_9 ⁢ s8 + g_syn_e_8_10 ⁢ s8 + g_syn_e_9_1 ⁢ s9 + g_syn_e_9_2 ⁢ s9 + g_syn_e_9_3 ⁢ s9 + g_syn_e_9_4 ⁢ s9 + g_syn_e_9_5 ⁢ s9 + g_syn_e_9_6 ⁢ s9 + g_syn_e_9_7 ⁢ s9 + g_syn_e_9_8 ⁢ s9 + g_syn_e_9_10 ⁢ s9 + g_syn_e_10_1 ⁢ s10 + g_syn_e_10_2 ⁢ s10 + g_syn_e_10_3 ⁢ s10 + g_syn_e_10_4 ⁢ s10 + g_syn_e_10_5 ⁢ s10 + g_syn_e_10_6 ⁢ s10 + g_syn_e_10_7 ⁢ s10 + g_syn_e_10_8 ⁢ s10 + g_syn_e_10_9 ⁢ s10

Component: single_neuron_model

Component: environment

Component: membrane

dd time V =- i_NaP + i_Na + i_K + i_L + i_tonic_e + i_syn_e + i_app C

Component: fast_sodium_current

i_Na = g_Na ⁢ m_infinity 3.0 ⁢ 1.0 - n ⁢ V - E_Na

Component: fast_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: fast_sodium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: potassium_current

i_K = g_K ⁢ n 4.0 ⁢ V - E_K

Component: potassium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: persistent_sodium_current

i_NaP = g_NaP ⁢ m_infinity ⁢ h ⁢ V - E_Na

Component: persistent_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: persistent_sodium_current_h_gate

dd time h = h_infinity - h tau_h h_infinity = 1.0 1.0 +ⅇ V - theta_h sigma_h tau_h = tau_h_max cosh⁡ V - theta_h 2.0 ⁢ sigma_h

Component: leakage_current

i_L = g_L ⁢ V - E_L

Component: tonic_current

i_tonic_e = g_tonic_e ⁢ V - E_syn_e

Component: synaptic_input

i_syn_e = sum_g_syn_e_s ⁢ V - E_syn_e s_infinity = 1.0 1.0 +ⅇ V - theta_s sigma_s s = 1.0 - s ⁢ s_infinity -- kr ⁢ s tau_s

Component: single_neuron_model

Component: environment

Component: membrane

dd time V =- i_NaP + i_Na + i_K + i_L + i_tonic_e + i_syn_e + i_app C

Component: fast_sodium_current

i_Na = g_Na ⁢ m_infinity 3.0 ⁢ 1.0 - n ⁢ V - E_Na

Component: fast_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: fast_sodium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: potassium_current

i_K = g_K ⁢ n 4.0 ⁢ V - E_K

Component: potassium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: persistent_sodium_current

i_NaP = g_NaP ⁢ m_infinity ⁢ h ⁢ V - E_Na

Component: persistent_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: persistent_sodium_current_h_gate

dd time h = h_infinity - h tau_h h_infinity = 1.0 1.0 +ⅇ V - theta_h sigma_h tau_h = tau_h_max cosh⁡ V - theta_h 2.0 ⁢ sigma_h

Component: leakage_current

i_L = g_L ⁢ V - E_L

Component: tonic_current

i_tonic_e = g_tonic_e ⁢ V - E_syn_e

Component: synaptic_input

i_syn_e = sum_g_syn_e_s ⁢ V - E_syn_e s_infinity = 1.0 1.0 +ⅇ V - theta_s sigma_s s = 1.0 - s ⁢ s_infinity -- kr ⁢ s tau_s

Component: single_neuron_model

Component: environment

Component: membrane

dd time V =- i_NaP + i_Na + i_K + i_L + i_tonic_e + i_syn_e + i_app C

Component: fast_sodium_current

i_Na = g_Na ⁢ m_infinity 3.0 ⁢ 1.0 - n ⁢ V - E_Na

Component: fast_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: fast_sodium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: potassium_current

i_K = g_K ⁢ n 4.0 ⁢ V - E_K

Component: potassium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: persistent_sodium_current

i_NaP = g_NaP ⁢ m_infinity ⁢ h ⁢ V - E_Na

Component: persistent_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: persistent_sodium_current_h_gate

dd time h = h_infinity - h tau_h h_infinity = 1.0 1.0 +ⅇ V - theta_h sigma_h tau_h = tau_h_max cosh⁡ V - theta_h 2.0 ⁢ sigma_h

Component: leakage_current

i_L = g_L ⁢ V - E_L

Component: tonic_current

i_tonic_e = g_tonic_e ⁢ V - E_syn_e

Component: synaptic_input

i_syn_e = sum_g_syn_e_s ⁢ V - E_syn_e s_infinity = 1.0 1.0 +ⅇ V - theta_s sigma_s s = 1.0 - s ⁢ s_infinity -- kr ⁢ s tau_s

Component: single_neuron_model

Component: environment

Component: membrane

dd time V =- i_NaP + i_Na + i_K + i_L + i_tonic_e + i_syn_e + i_app C

Component: fast_sodium_current

i_Na = g_Na ⁢ m_infinity 3.0 ⁢ 1.0 - n ⁢ V - E_Na

Component: fast_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: fast_sodium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: potassium_current

i_K = g_K ⁢ n 4.0 ⁢ V - E_K

Component: potassium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: persistent_sodium_current

i_NaP = g_NaP ⁢ m_infinity ⁢ h ⁢ V - E_Na

Component: persistent_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: persistent_sodium_current_h_gate

dd time h = h_infinity - h tau_h h_infinity = 1.0 1.0 +ⅇ V - theta_h sigma_h tau_h = tau_h_max cosh⁡ V - theta_h 2.0 ⁢ sigma_h

Component: leakage_current

i_L = g_L ⁢ V - E_L

Component: tonic_current

i_tonic_e = g_tonic_e ⁢ V - E_syn_e

Component: synaptic_input

i_syn_e = sum_g_syn_e_s ⁢ V - E_syn_e s_infinity = 1.0 1.0 +ⅇ V - theta_s sigma_s s = 1.0 - s ⁢ s_infinity -- kr ⁢ s tau_s

Component: single_neuron_model

Component: environment

Component: membrane

dd time V =- i_NaP + i_Na + i_K + i_L + i_tonic_e + i_syn_e + i_app C

Component: fast_sodium_current

i_Na = g_Na ⁢ m_infinity 3.0 ⁢ 1.0 - n ⁢ V - E_Na

Component: fast_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: fast_sodium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: potassium_current

i_K = g_K ⁢ n 4.0 ⁢ V - E_K

Component: potassium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: persistent_sodium_current

i_NaP = g_NaP ⁢ m_infinity ⁢ h ⁢ V - E_Na

Component: persistent_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: persistent_sodium_current_h_gate

dd time h = h_infinity - h tau_h h_infinity = 1.0 1.0 +ⅇ V - theta_h sigma_h tau_h = tau_h_max cosh⁡ V - theta_h 2.0 ⁢ sigma_h

Component: leakage_current

i_L = g_L ⁢ V - E_L

Component: tonic_current

i_tonic_e = g_tonic_e ⁢ V - E_syn_e

Component: synaptic_input

i_syn_e = sum_g_syn_e_s ⁢ V - E_syn_e s_infinity = 1.0 1.0 +ⅇ V - theta_s sigma_s s = 1.0 - s ⁢ s_infinity -- kr ⁢ s tau_s

Component: single_neuron_model

Component: environment

Component: membrane

dd time V =- i_NaP + i_Na + i_K + i_L + i_tonic_e + i_syn_e + i_app C

Component: fast_sodium_current

i_Na = g_Na ⁢ m_infinity 3.0 ⁢ 1.0 - n ⁢ V - E_Na

Component: fast_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: fast_sodium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: potassium_current

i_K = g_K ⁢ n 4.0 ⁢ V - E_K

Component: potassium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: persistent_sodium_current

i_NaP = g_NaP ⁢ m_infinity ⁢ h ⁢ V - E_Na

Component: persistent_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: persistent_sodium_current_h_gate

dd time h = h_infinity - h tau_h h_infinity = 1.0 1.0 +ⅇ V - theta_h sigma_h tau_h = tau_h_max cosh⁡ V - theta_h 2.0 ⁢ sigma_h

Component: leakage_current

i_L = g_L ⁢ V - E_L

Component: tonic_current

i_tonic_e = g_tonic_e ⁢ V - E_syn_e

Component: synaptic_input

i_syn_e = sum_g_syn_e_s ⁢ V - E_syn_e s_infinity = 1.0 1.0 +ⅇ V - theta_s sigma_s s = 1.0 - s ⁢ s_infinity -- kr ⁢ s tau_s

Component: single_neuron_model

Component: environment

Component: membrane

dd time V =- i_NaP + i_Na + i_K + i_L + i_tonic_e + i_syn_e + i_app C

Component: fast_sodium_current

i_Na = g_Na ⁢ m_infinity 3.0 ⁢ 1.0 - n ⁢ V - E_Na

Component: fast_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: fast_sodium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: potassium_current

i_K = g_K ⁢ n 4.0 ⁢ V - E_K

Component: potassium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: persistent_sodium_current

i_NaP = g_NaP ⁢ m_infinity ⁢ h ⁢ V - E_Na

Component: persistent_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: persistent_sodium_current_h_gate

dd time h = h_infinity - h tau_h h_infinity = 1.0 1.0 +ⅇ V - theta_h sigma_h tau_h = tau_h_max cosh⁡ V - theta_h 2.0 ⁢ sigma_h

Component: leakage_current

i_L = g_L ⁢ V - E_L

Component: tonic_current

i_tonic_e = g_tonic_e ⁢ V - E_syn_e

Component: synaptic_input

i_syn_e = sum_g_syn_e_s ⁢ V - E_syn_e s_infinity = 1.0 1.0 +ⅇ V - theta_s sigma_s s = 1.0 - s ⁢ s_infinity -- kr ⁢ s tau_s

Component: single_neuron_model

Component: environment

Component: membrane

dd time V =- i_NaP + i_Na + i_K + i_L + i_tonic_e + i_syn_e + i_app C

Component: fast_sodium_current

i_Na = g_Na ⁢ m_infinity 3.0 ⁢ 1.0 - n ⁢ V - E_Na

Component: fast_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: fast_sodium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: potassium_current

i_K = g_K ⁢ n 4.0 ⁢ V - E_K

Component: potassium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: persistent_sodium_current

i_NaP = g_NaP ⁢ m_infinity ⁢ h ⁢ V - E_Na

Component: persistent_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: persistent_sodium_current_h_gate

dd time h = h_infinity - h tau_h h_infinity = 1.0 1.0 +ⅇ V - theta_h sigma_h tau_h = tau_h_max cosh⁡ V - theta_h 2.0 ⁢ sigma_h

Component: leakage_current

i_L = g_L ⁢ V - E_L

Component: tonic_current

i_tonic_e = g_tonic_e ⁢ V - E_syn_e

Component: synaptic_input

i_syn_e = sum_g_syn_e_s ⁢ V - E_syn_e s_infinity = 1.0 1.0 +ⅇ V - theta_s sigma_s s = 1.0 - s ⁢ s_infinity -- kr ⁢ s tau_s

Component: single_neuron_model

Component: environment

Component: membrane

dd time V =- i_NaP + i_Na + i_K + i_L + i_tonic_e + i_syn_e + i_app C

Component: fast_sodium_current

i_Na = g_Na ⁢ m_infinity 3.0 ⁢ 1.0 - n ⁢ V - E_Na

Component: fast_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: fast_sodium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: potassium_current

i_K = g_K ⁢ n 4.0 ⁢ V - E_K

Component: potassium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: persistent_sodium_current

i_NaP = g_NaP ⁢ m_infinity ⁢ h ⁢ V - E_Na

Component: persistent_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: persistent_sodium_current_h_gate

dd time h = h_infinity - h tau_h h_infinity = 1.0 1.0 +ⅇ V - theta_h sigma_h tau_h = tau_h_max cosh⁡ V - theta_h 2.0 ⁢ sigma_h

Component: leakage_current

i_L = g_L ⁢ V - E_L

Component: tonic_current

i_tonic_e = g_tonic_e ⁢ V - E_syn_e

Component: synaptic_input

i_syn_e = sum_g_syn_e_s ⁢ V - E_syn_e s_infinity = 1.0 1.0 +ⅇ V - theta_s sigma_s s = 1.0 - s ⁢ s_infinity -- kr ⁢ s tau_s

Component: single_neuron_model

Component: environment

Component: membrane

dd time V =- i_NaP + i_Na + i_K + i_L + i_tonic_e + i_syn_e + i_app C

Component: fast_sodium_current

i_Na = g_Na ⁢ m_infinity 3.0 ⁢ 1.0 - n ⁢ V - E_Na

Component: fast_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: fast_sodium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: potassium_current

i_K = g_K ⁢ n 4.0 ⁢ V - E_K

Component: potassium_current_n_gate

dd time n = n_infinity - n tau_n n_infinity = 1.0 1.0 +ⅇ V - theta_n sigma_n tau_n = tau_n_max cosh⁡ V - theta_n 2.0 ⁢ sigma_n

Component: persistent_sodium_current

i_NaP = g_NaP ⁢ m_infinity ⁢ h ⁢ V - E_Na

Component: persistent_sodium_current_m_gate

m_infinity = 1.0 1.0 +ⅇ V - theta_m sigma_m

Component: persistent_sodium_current_h_gate

dd time h = h_infinity - h tau_h h_infinity = 1.0 1.0 +ⅇ V - theta_h sigma_h tau_h = tau_h_max cosh⁡ V - theta_h 2.0 ⁢ sigma_h

Component: leakage_current

i_L = g_L ⁢ V - E_L

Component: tonic_current

i_tonic_e = g_tonic_e ⁢ V - E_syn_e

Component: synaptic_input

i_syn_e = sum_g_syn_e_s ⁢ V - E_syn_e s_infinity = 1.0 1.0 +ⅇ V - theta_s sigma_s s = 1.0 - s ⁢ s_infinity -- kr ⁢ s tau_s