Location: Na+/H+ Exchanger @ ec47b51fda2c / documentation.html
- Author:
- Soroush Safaei <ssaf006@aucklanduni.ac.nz>
- Date:
- 2016-05-06 15:21:46+12:00
- Desc:
- Modifying the documentation
- Permanent Source URI:
- https://staging.physiomeproject.org/workspace/28f/rawfile/ec47b51fda2c33afe8535b56355e1b9c44dedf1f/documentation.html
Annotations
- Described by
- A kinetically defined Na+/H+ antiporter within a mathematical model of the rat proximal tubule, A.M. Weinstein, 1995, The Journal of General Physiology, 105, 617-641. DOI: 10.1085/jgp.105.5.617
- Protein
- Sodium/hydrogen exchanger 3
- Located in
- Proximal convoluted tubule
- Apical plasma membrane
- Epithelial cell of proximal tubule
Workspace Status
This workspace contains several verisons of the Weinstein (1995) NHE3 model, the mathematical model and then a version of the model to reproduce each figure in the original paper. These models can be browsed via the Navigation panel in the right hand column.
- Figure 2 illustrates the effect of external pH on Na+ influx.
- Figure 3 illustrates the effect of external pH on the Michaelis constant of Na+ flux.
- Figure 4 illustrates the effect of external pH on competitive inhibition by NH4+.